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Danicamtiv (MYK-491) - 98%, high purity , CAS No.1970972-74-7

COA

Grade & Purity:

≥98%

Cas Number: 1970972-74-7
Molecular Weight: 435.42
PubChem CID: 122424426
PubChem SID: 504772976

In stock

Item Number

D419990

Grouped product items
SKU	Size	Availability	Price
D419990-1mg	1mg	3	$197.90
D419990-5mg	5mg	3	$345.90
D419990-10mg	10mg	3	$573.90
D419990-25mg	25mg	3	$1,167.90
D419990-50mg	50mg	3	$1,682.90

View related series

Cytoskeleton (498) Myosin (30)

Basic Description

Synonyms	(R)-4-(1-((3-(Difluoromethyl)-1-methyl-1H-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-N-(isoxazol-3-yl)piperidine-1-carboxamide \| s9948 \| AKOS040741594 \| Danicamtiv \| SAR440181 \| SAR-440181 \| UNII-7B2CS922HI \| 7B2CS922HI \| D11824 \| Danicamtiv [INN] \| Danicamtiv
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product description： Danicamtiv is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Piperidines
    - Subclass Piperidinecarboxylic acids and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Piperidines
Subclass	Piperidinecarboxylic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Piperidinecarboxamides
Alternative Parents	Imidolactams Sulfonyls Isoxazoles Heteroaromatic compounds Organic carbonic acids and derivatives Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Piperidinecarboxamide - 1-piperidinecarboxamide - Imidolactam - Heteroaromatic compound - Sulfonyl - Isoxazole - Azole - Carbonic acid derivative - Oxacycle - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Alkyl halide - Alkyl fluoride - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as piperidinecarboxamides. These are compounds containing a piperidine ring substituted with a carboxamide functional group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504772976
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504772976
IUPAC Name	4-[(1R)-1-[3-(difluoromethyl)-1-methylpyrazol-4-yl]sulfonyl-1-fluoroethyl]-N-(1,2-oxazol-3-yl)piperidine-1-carboxamide
INCHI	InChI=1S/C16H20F3N5O4S/c1-16(19,29(26,27)11-9-23(2)21-13(11)14(17)18)10-3-6-24(7-4-10)15(25)20-12-5-8-28-22-12/h5,8-10,14H,3-4,6-7H2,1-2H3,(H,20,22,25)/t16-/m1/s1
InChIKey	NREKKBAMVWQRES-MRXNPFEDSA-N
Smiles	CC(C1CCN(CC1)C(=O)NC2=NOC=C2)(F)S(=O)(=O)C3=CN(N=C3C(F)F)C
Isomeric SMILES	C[C@@](C1CCN(CC1)C(=O)NC2=NOC=C2)(F)S(=O)(=O)C3=CN(N=C3C(F)F)C
Molecular Weight	435.42
Reaxy-Rn	39943554
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=39943554&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
G2226405	Certificate of Analysis	May 09, 2025	D419990
G2226406	Certificate of Analysis	May 09, 2025	D419990
G2226407	Certificate of Analysis	May 09, 2025	D419990
G2226377	Certificate of Analysis	May 09, 2025	D419990
G2226422	Certificate of Analysis	May 09, 2025	D419990

Chemical and Physical Properties

Molecular Weight	435.400 g/mol
XLogP3	1.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	5
Exact Mass	435.119 Da
Monoisotopic Mass	435.119 Da
Topological Polar Surface Area	119.000 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	701.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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