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(D)-PPA 1, CAS No.1620813-53-7
PD-1/PD-L1 interaction inhibitor
Basic Description
Product Name
(D)-PPA 1, CAS No.1620813-53-7
Biochemical and Physiological Mechanisms
PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd= 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of micein vivo.
Sequence
NYSKPTDRQYHF(Modifications: Asn-1 = D-Asn, Tyr-2 = D-Tyr, Ser-3 = D-Ser, Lys-4 = D-Lys, Pro-5 = D-Pro, Thr-6 = D-Thr, Asp-7 = D-Asp, Arg-8 = D-Arg, Gln-9 = D-Gln, Tyr-10 = D-Tyr, His-11 = D-His, Phe-12 = D-Phe)
Storage and Shipping
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
CAS
1620813-53-7
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
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