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D-Lactic Acid - >90.0%(T), high purity , CAS No.10326-41-7, Agonist of HCA 1 receptor
Basic Description
Synonyms
(D)-(-)-Lactic acid | (R)-lactate | (R)-2-Hydroxypropionate | D-2-Hydroxypropionic acid | D-(-)-Lactate | D-LACTIC ACID [WHO-DD] | AS-19478 | HY-111095 | (R)-2-Hydroxypropionic acid(R)-2-Hydroxypropionic acid | (R)-alpha-Hydroxypropionate | D-Lactic acid
Specifications & Purity
Moligand™, ≥90%(T)
Biochemical and Physiological Mechanisms
In animals, lactic acid is a metabolic compound produced by proliferating cells and during anaerobic conditions such as strenuous exercise. Lactic acid can be oxidized back to pyruvate or converted to glucose via gluconeogenesis. Lactic acid is preferenti
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of HCA 1 receptor
Product Description
Lactic acid is used as a reagent in organic synthesis (in the manufacture of adhesives). It is used in the leather, textile, and tanning industries. It may be used as a plasticizer, a catalyst, or an acidifying agent. Lactic acid has even been used as a flavoring agent in the manufacture of tobacco products.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organic acids and derivatives
Class
Hydroxy acids and derivatives
Subclass
Alpha hydroxy acids and derivatives
Intermediate Tree Nodes
Not available
Direct Parent
Alpha hydroxy acids and derivatives
Alternative Parents
Secondary alcohols Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework
Aliphatic acyclic compounds
Substituents
Alpha-hydroxy acid - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
Description
This compound belongs to the class of organic compounds known as alpha hydroxy acids and derivatives. These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
External Descriptors
2-hydroxypropanoic acid
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action
Action Type
target ID
Target Name
Target Type
Target Organism
Binding Site Name
References
Names and Identifiers
IUPAC Name
(2R)-2-hydroxypropanoic acid
INCHI
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m1/s1
InChIKey
JVTAAEKCZFNVCJ-UWTATZPHSA-N
Smiles
CC(C(=O)O)O
Isomeric SMILES
C[C@H](C(=O)O)O
Molecular Weight
90.08
Reaxy-Rn
1209341
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1209341&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Solubility
Soluble in water (50mg/ml)
Sensitivity
heat sensitive
Refractive Index
1.43
Specific Rotation[α]
13° (C=2.5,1.5mol/L NaOH)
Flash Point(°C)
110 °C
Molecular Weight
90.080 g/mol
XLogP3
-0.700
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
90.0317 Da
Monoisotopic Mass
90.0317 Da
Topological Polar Surface Area
57.500 Ų
Heavy Atom Count
6
Formal Charge
0
Complexity
59.100
Isotope Atom Count
0
Defined Atom Stereocenter Count
1
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Citations of This Product
1.
Rongxiu Qin, Haiyan Chen, Rusi Wen, Guiqing Li, Zhonglei Meng.
(2023)
Effect of Boric Acid on the Ionization Equilibrium of α-Hydroxy Carboxylic Acids and the Study of Its Applications. MOLECULES,
28
(12):
(4723).
2.
Xiao Zheng, Ying Liu, Yiqiong Liu, Tingting Zhang, Yuge Zhao, Jie Zang, Yan Yang, Ruiqing He, Gaowei Chong, Shuangrong Ruan, Dailin Xu, Yongyong Li, Haiqing Dong.
(2022)
Dual Closed-Loop of Catalyzed Lactate Depletion and Immune Response to Potentiate Photothermal Immunotherapy. ACS Applied Materials & Interfaces,
14
(20):
(23260–23276).
3.
Jie Sun, Yaping Wang, Zhenguo Gao, Junbo Gong, Weiwei Tang.
(2022)
Additive-assisted preferential crystallization of racemic component: A case of norvaline. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,
110
(206).
4.
Jianjian Zhao, Aiyou Hao, Pengyao Xing.
(2021)
Enhancing Optical Activities of Benzimidazole Derivatives through Coassembly for High-Efficiency Synthesis of Chiroptical Nanomaterials and Accurate ee % Detection of Natural Acids. ACS Applied Materials & Interfaces,
13
(5):
(6830–6843).
5.
Kaiyang Ma, Xiao Ding, Qiqi Song, Zhitao Han, Hang Yao, Jianhua Ding, Gang Hu.
(2020)
Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes. NEUROPHARMACOLOGY,
171
(108084).
6.
Shengli Mi, Jingjing Xia, Yuanyuan Xu, Zhichang Du, Wei Sun.
(2019)
An integrated microchannel biosensor platform to analyse low density lactate metabolism in HepG2 cells in vitro. RSC Advances,
9
(16):
(9006-9013).
7.
Ai-Ling Hu, Yin-Huan Liu, Hao-Hua Deng, Guo-Lin Hong, Ai-Lin Liu, Xin-Hua Lin, Xing-Hua Xia, Wei Chen.
(2014)
Fluorescent hydrogen peroxide sensor based on cupric oxide nanoparticles and its application for glucose and l-lactate detection. BIOSENSORS & BIOELECTRONICS,
61
(374).
8.
Chen Chen, Ziwei Liu, Jianzheng Li, Davide Vurro, Yizhou Jiang, Luyu Xue, Ye Gong, Yaje Qin.
(2024)
A Miniaturized Flexible Patch Based on CNT Fiber Sensors and Highly Integrated SoC for Analysis of Sweat. IEEE SENSORS JOURNAL,
24
(22):
(1-1).
9.
Qing Li, Congnan Wu, Jiaxing Zhang, Rongxin Su, Yuefei Wang, Wei Qi.
(2024)
Construction of chiral nanozymes with high enantioselectivity for visual detection via smartphone-based paper sensors. CHEMICAL ENGINEERING JOURNAL,
495
(153326).
10.
Xinwen Jia, Mengyun Lu, Wenjing Zhang, Wuduo Zhao, Ajuan Yu, Shusheng Zhang.
(2025)
Fluorescence enantioselective sensing of lactic acid enantiomers by Zn-MOC@CQDs with double chiral building blocks. MICROCHEMICAL JOURNAL,
208
(112575).
11.
Jing Zhang, Zishuo Fang, Heng Dong, Yu Liu, Zhenyu Chu, Yongbin Mou, Wanqin Jin.
(2024)
MnFe@N-CNTs Based Lactate Biomicrochips for Nonintrusive and Onsite Periodontitis Diagnosis. ACS Applied Materials & Interfaces,
16
(16):
(20221-20231).
12.
Ling Ding, Lou Gao, Di Pan, Ke Du, Jiayu Yu, Wanyi Li, Yahong Zhang, Yi Tang.
(2024)
Reducing meso-lactide formation from racemic lactic acid using shape-selective H-Beta zeolite. Catalysis Science & Technology,
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12 Citations
E2520399