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| SKU | Size | Availability |
Price | Qty |
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D274852-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$166.90
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Cell-permeable analog of endogenous ceramide-1-phosphate
| Synonyms | [3-Hydroxy-2-(octanoylamino)octadec-4-enyl]dihydrogenphosphate |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Cell-permeable analog of endogenous ceramide-1-phosphate, a putative second messenger of sphingomyelin metabolism. Stimulates DNA synthesis and cell division in fibroblasts. Negative regulator of TNF-α production. |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Sphingolipids |
| Subclass | Phosphosphingolipids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phosphosphingolipids |
| Alternative Parents | Phosphoethanolamines Monoalkyl phosphates N-acyl amines Secondary carboxylic acid amides Secondary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Sphingoid-1-phosphate or derivatives - Phosphoethanolamine - Monoalkyl phosphate - Fatty amide - N-acyl-amine - Organic phosphoric acid derivative - Phosphoric acid ester - Alkyl phosphate - Fatty acyl - Secondary carboxylic acid amide - Secondary alcohol - Carboxamide group - Carboxylic acid derivative - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organic oxygen compound - Alcohol - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as phosphosphingolipids. These are sphingolipids with a structure based on a sphingoid base that is attached to a phosphate head group. They differ from phosphonospingolipids which have a phosphonate head group. |
| External Descriptors | Ceramide 1-phosphates |
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| IUPAC Name | [(E,2S,3R)-3-hydroxy-2-(octanoylamino)octadec-4-enyl] dihydrogen phosphate |
|---|---|
| INCHI | InChI=1S/C26H52NO6P/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(28)24(23-33-34(30,31)32)27-26(29)22-20-17-8-6-4-2/h19,21,24-25,28H,3-18,20,22-23H2,1-2H3,(H,27,29)(H2,30,31,32)/b21-19+/t24-,25+/m0/s1 |
| InChIKey | VSSNYUXSRXINIP-WRBRXSDHSA-N |
| Smiles | CCCCCCCCCCCCCC=CC(C(COP(=O)(O)O)NC(=O)CCCCCCC)O |
| Isomeric SMILES | CCCCCCCCCCCCC/C=C/[C@H]([C@H](COP(=O)(O)O)NC(=O)CCCCCCC)O |
| PubChem CID | 10864091 |
| Molecular Weight | 505.7 |
| Solubility | Soluble in DMSO to 25 mM and in ethanol to 25 mM |
|---|---|
| Molecular Weight | 505.700 g/mol |
| XLogP3 | 7.400 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 24 |
| Exact Mass | 505.353 Da |
| Monoisotopic Mass | 505.353 Da |
| Topological Polar Surface Area | 116.000 Ų |
| Heavy Atom Count | 34 |
| Formal Charge | 0 |
| Complexity | 551.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |