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CUDA , CAS No.479413-68-8

4 Citations

COA

Grade & Purity:

≥95%

Cas Number: 479413-68-8
Molecular Weight: 340.50
PubChem CID: 22978774

In stock

Item Number

C346200

Grouped product items
SKU	Size	Availability	Price
C346200-5mg	5mg	3	$38.90
C346200-10mg	10mg	3	$61.90
C346200-25mg	25mg	2	$123.90
C346200-50mg	50mg	1	$209.90
C346200-100mg	100mg	1	$334.90

an sEH inhibitor and selective PPARα activator

View related series

Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Epoxide Hydrolase (22) Lipid metabolism (1912) Metabolic Enzyme/Protease (4860) PPAR (155) Vitamin D Related/Nuclear Receptor (907)

Basic Description

Synonyms	12-(cyclohexylcarbamoylamino)dodecanoic acid \| HY-121538 \| 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid \| DTXSID60629291 \| SR-01000946808-1 \| HMS3650M07 \| CHEBI:181802 \| BDBM129262 \| US8815951, 425 \| SR-01000946808 \| 12-[(CYCLOHEXYLCARBAMOYL)AMIN
Specifications & Purity	≥95%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	CUDA is an inhibitor of soluble epoxide hydrolase (sEH, IC\|50\|= 11.1 nM in mice). Studies have shown that 10 μM of CUDA can block the conversion of 14,15-EET to 14,15-DHET by 94% in COS-7 cells. CUDA selectively activates peroxisome proliferator-activated receptor α (PPARα) 8-fold at a concentration of 10 μM with no affect on PPARδ or PPARγ.CUDA may be valuable for the study of cardiovascular diseases.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Fatty Acyls
    - Subclass Fatty acids and conjugates

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Fatty Acyls
Subclass	Fatty acids and conjugates
Intermediate Tree Nodes	Not available
Direct Parent	Medium-chain fatty acids
Alternative Parents	Amino fatty acids Ureas Monocarboxylic acids and derivatives Carboxylic acids Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic homomonocyclic compounds
Substituents	Medium-chain fatty acid - Amino fatty acid - Urea - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

EPHX1 Tchem Epoxide hydrolase 1 (1 Activities)

Discover Target: EPHX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	12-(cyclohexylcarbamoylamino)dodecanoic acid
INCHI	InChI=1S/C19H36N2O3/c22-18(23)15-11-6-4-2-1-3-5-7-12-16-20-19(24)21-17-13-9-8-10-14-17/h17H,1-16H2,(H,22,23)(H2,20,21,24)
InChIKey	HPTJABJPZMULFH-UHFFFAOYSA-N
Smiles	C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O
Isomeric SMILES	C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O
Molecular Weight	340.50
Reaxy-Rn	9358961
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9358961&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
F2420123	Certificate of Analysis	Feb 28, 2024	C346200
F2420124	Certificate of Analysis	Feb 28, 2024	C346200
F2420125	Certificate of Analysis	Feb 28, 2024	C346200
F2420126	Certificate of Analysis	Feb 28, 2024	C346200
F2420127	Certificate of Analysis	Feb 28, 2024	C346200
F2420128	Certificate of Analysis	Feb 28, 2024	C346200
F2420129	Certificate of Analysis	Feb 28, 2024	C346200
F2420130	Certificate of Analysis	Feb 28, 2024	C346200
F2420131	Certificate of Analysis	Feb 28, 2024	C346200
F2420507	Certificate of Analysis	Feb 28, 2024	C346200

Chemical and Physical Properties

Molecular Weight	340.500 g/mol
XLogP3	5.000
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	13
Exact Mass	340.273 Da
Monoisotopic Mass	340.273 Da
Topological Polar Surface Area	78.400 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	342.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Xu-Hui Huang, Rong Liu, Jia-Nan Chen, Xiu-Ping Dong, Bei-Wei Zhu, Lei Qin. (2022) Self-detoxification behaviors and tissue-specific metabolic responses of fishes growing in erythromycin-contaminated water. Journal of Cleaner Production, 379 (134577).
2. Jie Hao, Xusong Wang, Liqun Li, Zhikang Sun, Xuanwen Li, Qiang Ji, Xuhui Huang, Lei Qin. (2025) A multi-omics fusion of metabolomics, lipidomics, and flavoromics to analyze the effect of enzyme treatment on tobacco quality. INDUSTRIAL CROPS AND PRODUCTS, 226 (120721).
3. Jie Hao, Xusong Wang, Ying Chai, Xuhui Huang, Han Wu, Shanlin Zhang, Xiaojiao Duan, Lei Qin. (2024) Evaluation of lipid and metabolite profiles in tobacco leaves from different plant parts by comprehensive lipidomics and metabolomics analysis. INDUSTRIAL CROPS AND PRODUCTS, 212 (118318).
4. Jie Hao, Xusong Wang, Liqun Li, Xuhui Huang, Na Wu, Tao Yu, Lu An, Lei Qin. (2025) Targeted regulation of hazardous substances from cigarette mainstream smoke based on the application of enzymes. INDUSTRIAL CROPS AND PRODUCTS, 226 (120613).

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