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CTB - 99%, high purity , CAS No.451491-47-7

COA

Grade & Purity:

≥99%

Cas Number: 451491-47-7
Molecular Weight: 343.73
PubChem CID: 729859

In stock

Item Number

C646637

Grouped product items
SKU	Size	Availability	Price
C646637-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$75.90
C646637-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$130.90
C646637-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$250.90
C646637-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$400.90
C646637-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$640.90

View related series

Apoptosis (4276) Epigenetics (1496) Histone Acetyltransferase (79) Histone Modification (1379)

Basic Description

Synonyms	CTB \| DTXSID401016272 \| MS-25265 \| STL229939 \| Cholera Toxin B Subunit \| N-(4-chloro-3-(trifluoromethyl)phenyl)-2-ethoxybenzamide \| Cholera Toxin B subunit, FITC conjugate, lyophilized powder \| HMS3426C07 \| YDXZSNHARVUYNM-UHFFFAOYSA-N \| N-[4-chloro-3-(tri
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	CTB is a potent p300 histone acetyltransferase activator. CTB can effectively induce apoptosis in MCF-7 cells.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	CTB is a potent p300 histone acetyltransferase activator CTB can effectively induce apoptosis in MCF-7 cells . In Vitro CTB (10, 50, 100, 150, 200, and 250 μM; 10 min) enhances p300 HAT activity of p300 in a dosedependent manner. ?\nCTB (0-200 μM; 24 hours) inhibits the viability of MCF-7 cells with an IC 50 of 85.43 μM. ?\nCTB (85.43 μM; 24, 48 and 72 h) induces time dependence apoptosis of MCF-7 cells. ?\nCTB (50 uM; 24?h) increases p300/CBP activity , and reduces autophagic flux in primary neurons. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: MCF-7 cell Concentration: 0-200 μM Incubation Time: 24 hours Result: Inhibit viability with an IC 50 of 85.43 μM. Apoptosis AnalysisCell Line: MCF-7 cell Concentration: 85.43 μM Incubation Time: 24, 48 and 72 h Result: Iinduced time-dependence apoptosis. Form:Solid IC50& Target:CBP/p300

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Anilides
      - Level5 Aromatic anilides
        Level6 Benzanilides

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Anilides
Intermediate Tree Nodes	Aromatic anilides
Direct Parent	Benzanilides
Alternative Parents	Trifluoromethylbenzenes Benzamides Benzoyl derivatives Phenol ethers Phenoxy compounds Chlorobenzenes Alkyl aryl ethers Aryl chlorides Secondary carboxylic acid amides Organonitrogen compounds Organofluorides Organochlorides Organic oxides Hydrocarbon derivatives Organopnictogen compounds Alkyl fluorides
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Benzanilide - Trifluoromethylbenzene - Benzamide - Benzoic acid or derivatives - Phenoxy compound - Phenol ether - Benzoyl - Alkyl aryl ether - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Ether - Organopnictogen compound - Organofluoride - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Alkyl fluoride - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Alkyl halide - Organochloride - Organohalogen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as benzanilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with a benzene ring. They have the general structure RNC(=O)R', where R,R'= benzene.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxybenzamide
INCHI	InChI=1S/C16H13ClF3NO2/c1-2-23-14-6-4-3-5-11(14)15(22)21-10-7-8-13(17)12(9-10)16(18,19)20/h3-9H,2H2,1H3,(H,21,22)
InChIKey	YDXZSNHARVUYNM-UHFFFAOYSA-N
Smiles	CCOC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F
Isomeric SMILES	CCOC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F
WGK Germany	2
PubChem CID	729859
Molecular Weight	343.73

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 100 mg/mL (290.93 mM; Need ultrasonic)
Molecular Weight	343.730 g/mol
XLogP3	4.600
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	343.059 Da
Monoisotopic Mass	343.059 Da
Topological Polar Surface Area	38.300 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	405.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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