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Concanavalin A from Canavalia ensiformis (Jack bean), CAS No.11028-71-0

    Grade & Purity:
  • Type IV, lyophilized powder
In stock
Item Number
C755208
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C755208-25mg
25mg
Available within 8-12 weeks(?)
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$32.90
C755208-100mg
100mg
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$80.90
C755208-250mg
250mg
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$167.90
C755208-1g
1g
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Basic Description

Product Name Concanavalin A from Canavalia ensiformis (Jack bean), CAS No.11028-71-0
Product Description

Concanavalin A (con A) is a plant lectin refined from jack beans. It is a tetrameric protein, which has four identical 28 kDa subunits. Con A has the ability to connect with the mannose residues of several glycoproteins and can stimulate lymphocytes.
Application:
Concanavalin A from Canavalia ensiformis (Jack bean) has been used:
  • as T-lymphocyte mitogen in lymphocyte proliferation assay for correlations with organochlorine contaminants (OCs)
  • for in vitro stimulation of T cell hybridomas, BW5147 cells and primary CD4+ T cells for T cell vaccination and for induction of hepatitis
  • for the stimulation of mice splenocytes in the suppression of T-lymphocytes proliferation assay
  • for the stimulation of spleen in mitogen assays

Specifications & Purity Type IV, lyophilized powder
Biochemical and Physiological Mechanisms Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetrame

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Nucleosides, nucleotides, and analogues
Class Pyrimidine nucleosides
Subclass Pyrimidine 2',3'-dideoxyribonucleosides
Intermediate Tree Nodes Not available
Direct Parent Pyrimidine 2',3'-dideoxyribonucleosides
Alternative Parents Benzenesulfonamides  Benzoic acids  Benzenesulfonyl compounds  Benzoyl derivatives  Pyrimidones  Organosulfonamides  Hydropyrimidines  Vinylogous amides  Tetrahydrofurans  Heteroaromatic compounds  Aminosulfonyl compounds  Ureas  Lactams  Azo imides  Azo compounds  Oxacyclic compounds  Monocarboxylic acids and derivatives  Carboxylic acids  Azacyclic compounds  Primary alcohols  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Not available
Substituents Pyrimidine 2',3'-dideoxyribonucleoside - Benzenesulfonamide - Benzenesulfonyl group - Benzoic acid - Benzoic acid or derivatives - Benzoyl - Pyrimidone - Benzenoid - Organosulfonic acid amide - Pyrimidine - Hydropyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Vinylogous amide - Aminosulfonyl compound - Tetrahydrofuran - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Urea - Lactam - Azo imide - Azo compound - Oxacycle - Azacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Alcohol - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyrimidine 2',3'-dideoxyribonucleosides. These are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at positions 2 and 3.
External Descriptors Not available

Storage and Shipping

Concentration Type IV, lyophilized powder
Storage Temp Store at -20°C
Shipped In Ice chest + Ice pads
CAS 11028-71-0

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Citations of This Product

1. Mengyuan Chen, Chong Wang, Jing Tan, Jin Wang, Chen Wang.  (2025)  Cell membrane-inspired COF/AAO hybrid nanofluidic membrane with ion current rectification properties for ultrasensitive detection of E. coli.  SENSORS AND ACTUATORS B-CHEMICAL,  423  (136719). 
2. Chenze Lu, Gongyan Wang, Xiaoxiao Zhang, Zhihui Fang, Xinyuan Wang, Fan Tang, Kang Ning, Min Xu, Jing Wang, Han Jiang, Ran Tao, Pei Xu.  (2025)  Cost-effective, label-free electrochemical aptasensors for rapid detection of concanavalin A with screen printed electrodes.  FOOD CHEMISTRY,  476  (143338). 
3. He Li, Changxin Zheng, Yanru Zheng, Kai Wen, Yingjiu Zhang.  (2024)  Distinct functional diversity of branched oligosaccharides as chaperones and inhibitory-binding partners of amyloid beta-protein and its aggregates.  NEUROPHARMACOLOGY,    (110141). 
4. Jinming Zhang, Jihang Zhang, Jiale Chen, Xiao Zhang, Jinglan Wu, Pengpeng Yang, Fengxia Zou, Hanjie Ying, Wei Zhuang.  (2025)  Exploiting unique NP1 interface: Oriented immobilization via electrostatic and affinity interactions in a tailored PDA/PEI microenvironment enhanced by concanavalin A.  TALANTA,  286  (127528). 
5. Chendi Gao, Ensong Zhang, Xinyu Bian, Qiaoran Li, Chunming Wang, Guang Yang, Ming Jiang, Guosong Chen.  (2024)  One-Pot Fabrication of Supramolecular Synthetic Protein Hydrogel with Tissue-like Integrated Dynamic Features.  BIOMACROMOLECULES,  25  (3): (2065-2074). 

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