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Cisatracurium Besylate - ≥98%, high purity , Muscle-type nicotinic acetylcholine receptor antagonist, CAS No.96946-42-8, Muscle-type nicotinic acetylcholine receptor antagonist

    Grade & Purity:
  • ≥98%
In stock
Item Number
C129903
Grouped product items
SKU Size
Availability
Price Qty
C129903-250mg
250mg
3
$39.90
C129903-1g
1g
3
$96.90
C129903-5g
5g
2
$249.90

Basic Description

Synonyms 51W89 | 51-W89 | 51-W-89 | ISOQUINOLINIUM, 2,2'-(1,5-PENTANEDIYLBIS(OXY(3-OXO-3,1-PROPANEDIYL)))BIS(1-((3,4-DIMETHOXYPHENYL)METHYL)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-, DIBENZENESULFONATE, (1R-(1alpha,2alpha(1'R*,2'R*)))- | (1R,2R,1'R,2'R)-2,2'-{pe
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Cisatracurium besylate is one of the ten stereoisomers of astracurium that does not cause histamine release. This compound is a potent, nondepolarizing neuromuscular blocking agent. It acts on cholinergic receptors to block neuromuscular transmission, whi
Storage Temp Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type ANTAGONIST
Mechanism of action Muscle-type nicotinic acetylcholine receptor antagonist
Product Description

Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
A neuromuscular blocking agent.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Benzenesulfonic acids and derivatives
Intermediate Tree Nodes Not available
Direct Parent Benzenesulfonic acids and derivatives
Alternative Parents Benzenesulfonyl compounds  1-sulfo,2-unsubstituted aromatic compounds  Dicarboxylic acids and derivatives  Sulfonyls  Organosulfonic acids  Organic zwitterions  Organic salts  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Not available
Substituents Benzenesulfonate - Arylsulfonic acid or derivatives - Benzenesulfonyl group - 1-sulfo,2-unsubstituted aromatic compound - Dicarboxylic acid or derivatives - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Organic oxide - Organic oxygen compound - Organosulfur compound - Hydrocarbon derivative - Organic salt - Organic zwitterion - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as benzenesulfonic acids and derivatives. These are organic compounds containing a sulfonic acid or a derivative thereof that is linked to a benzene ring.
External Descriptors quaternary ammonium salt - organosulfonate salt - atracurium besylate

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Homo sapiens (32628 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504753889
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504753889
IUPAC Name benzenesulfonate;5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
INCHI InChI=1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2/t42-,43-,54-,55-;;/m1../s1
InChIKey XXZSQOVSEBAPGS-DONVQRBFSA-L
Smiles C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]
Isomeric SMILES C[N@@+]1(CCC2=CC(=C(C=C2[C@H]1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N@+]4(CCC5=CC(=C(C=C5[C@H]4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]
WGK Germany 3
Alternate CAS 96946-42-8
MeSH Entry Terms 51W89;cisatracurium;cisatracurium besilate;cisatracurium besylate;Nimbex
Molecular Weight 1243.48
Reaxy-Rn 3535417
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3535417&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number Certificate Type Date Item
G2203132 Certificate of Analysis Jun 11, 2024 C129903
G2203144 Certificate of Analysis Apr 07, 2024 C129903
G2203060 Certificate of Analysis Apr 07, 2024 C129903
A2409222 Certificate of Analysis Nov 23, 2023 C129903
A2409223 Certificate of Analysis Nov 23, 2023 C129903

Chemical and Physical Properties

Solubility DMSO 249 mg/mL Water 47 mg/mL Ethanol 249 mg/mL
Sensitivity Light and moisture sensitive
Melt Point(°C) 85-90°C
Molecular Weight 1243.500 g/mol
XLogP3
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 18
Rotatable Bond Count 26
Exact Mass 1242.5 Da
Monoisotopic Mass 1242.5 Da
Topological Polar Surface Area 258.000 Ų
Heavy Atom Count 87
Formal Charge 0
Complexity 1560.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 3

Solution Calculators

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