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Chloramphenicol succinate sodium salt - ≥80% (HPLC), high purity , Bacterial 70S ribosome inhibitor, CAS No.982-57-0, Bacterial 70S ribosome inhibitor

1 Citations

COA

Grade & Purity:

≥80%(HPLC)

Cas Number: 982-57-0
Molecular Weight: 445.19
MDL number: MFCD00079025
PubChem CID: 656833

In stock

Item Number

C463077

Grouped product items
SKU	Size	Availability	Price
C463077-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$152.90
C463077-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$606.90
C463077-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,651.90

View related series

Antibiotic (1629) Bacterial (3013)

Basic Description

Synonyms	sodium 4-((2R,3R)-2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propoxy)-4-oxobutanoate \| Protophenicol \| CCRIS 6204 \| CHLORAMPHENICOL SODIUM SUCCINATE [USP MONOGRAPH] \| Chloramphenicol succinate sodium \| LEVOMYCETIN-NALCEIN \| sodium;4-[(2R,3R)-2-[
Specifications & Purity	≥80%(HPLC)
Action Type	INHIBITOR
Mechanism of action	Bacterial 70S ribosome inhibitor
Product Description	Description Chemical structure: phenicoleChloramphenicol is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as a selection agent for transformed cells containing chloramphenicol reistance genes. Preparation instructions Stock solutions can be prepared directly in the vial at any recommended concentration. A solution at 50 mg/mL in ethanol yields a clear, very faint, yellow solution. Degradation of chloramphenicol in aqueous solution is catalyzed by general acids and bases. This rate of degradation is independent of the ionic strength and pH.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Nitrobenzenes

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Nitrobenzenes
Intermediate Tree Nodes	Not available
Direct Parent	Nitrobenzenes
Alternative Parents	Nitroaromatic compounds Fatty acid esters Dicarboxylic acids and derivatives Secondary carboxylic acid amides Secondary alcohols Carboxylic acid esters Carboxylic acid salts Propargyl-type 1,3-dipolar organic compounds Carboxylic acids Organic metal halides Organic oxoazanium compounds Organic zwitterions Hydrocarbon derivatives Organochlorides Organonitrogen compounds Aromatic alcohols Organopnictogen compounds Carbonyl compounds Organic oxides Alkyl chlorides Organic sodium salts
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Nitrobenzene - Nitroaromatic compound - Fatty acid ester - Dicarboxylic acid or derivatives - Fatty acyl - Carboxamide group - Carboxylic acid ester - Carboxylic acid salt - C-nitro compound - Organic nitro compound - Secondary alcohol - Secondary carboxylic acid amide - Carboxylic acid derivative - Carboxylic acid - Organic metal halide - Organic alkali metal salt - Organic oxoazanium - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organic oxygen compound - Organonitrogen compound - Organochloride - Carbonyl group - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Alkyl halide - Alkyl chloride - Organopnictogen compound - Organooxygen compound - Organic sodium salt - Organic salt - Aromatic alcohol - Organic zwitterion - Organic nitrogen compound - Alcohol - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	sodium;4-[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoate
INCHI	InChI=1S/C15H16Cl2N2O8.Na/c16-14(17)15(24)18-10(7-27-12(22)6-5-11(20)21)13(23)8-1-3-9(4-2-8)19(25)26;/h1-4,10,13-14,23H,5-7H2,(H,18,24)(H,20,21);/q;+1/p-1/t10-,13-;/m1./s1
InChIKey	RPLOPBHEZLFENN-HTMVYDOJSA-M
Smiles	C1=CC(=CC=C1C(C(COC(=O)CCC(=O)[O-])NC(=O)C(Cl)Cl)O)[N+](=O)[O-].[Na+]
Isomeric SMILES	C1=CC(=CC=C1[C@H]([C@@H](COC(=O)CCC(=O)[O-])NC(=O)C(Cl)Cl)O)[N+](=O)[O-].[Na+]
Molecular Weight	445.19
Reaxy-Rn	4102380
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4102380&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	H2O: 50mg/mL
Melt Point(°C)	>42ºC
Molecular Weight	445.200 g/mol
XLogP3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	9
Exact Mass	444.01 Da
Monoisotopic Mass	444.01 Da
Topological Polar Surface Area	162.000 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	541.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Chang Liu, Diandian Deng, Di Xu, Kang Wu, Hong Yang, Kang Zhao, Jianguo Li, Anping Deng. (2019) Development of a monoclonal antibody based-ELISA for the detection of chloramphenicol in shrimp, feed and milk samples and validation by LC-MS/MS coupled with immunoaffinity clean-up. Analytical Methods, 11 (4): (507-516).

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