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Chitosan Oligosaccharide - Molecular weight ≤1000, high purity , CAS No.148411-57-8

    Grade & Purity:
  • Molecular weight ≤1000
In stock
Item Number
C406214
Grouped product items
SKU Size
Availability
Price Qty
C406214-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$21.90
C406214-25g
25g
3
$75.90
C406214-100g
100g
1
$284.90

Basic Description

Synonyms A-D-glucopyranose | (2R,3S,4R,5R,6S)-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-2-(hydroxymethyl)oxane-3,4-diol | beta-D-glucosaminyl-(1->4)-beta-D-glucosamine | Q27122179 | (2R,3R,4R,5S,6R)-3-amino-5-{[(2S,3R,4R,5S,6
Specifications & Purity Molecular weight ≤1000
Product Description

application:

Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic oxygen compounds
Class Organooxygen compounds
Subclass Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes Aminosaccharides
Direct Parent Aminoglycosides
Alternative Parents O-glycosyl compounds  Disaccharides  Oxanes  Secondary alcohols  Hemiacetals  1,2-aminoalcohols  Oxacyclic compounds  Acetals  Primary alcohols  Organopnictogen compounds  Monoalkylamines  Hydrocarbon derivatives  
Molecular Framework Aliphatic heteromonocyclic compounds
Substituents Aminoglycoside core - Disaccharide - Glycosyl compound - O-glycosyl compound - Oxane - 1,2-aminoalcohol - Hemiacetal - Secondary alcohol - Organoheterocyclic compound - Acetal - Oxacycle - Organonitrogen compound - Alcohol - Primary aliphatic amine - Hydrocarbon derivative - Organopnictogen compound - Organic nitrogen compound - Amine - Primary alcohol - Primary amine - Aliphatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars.
External Descriptors beta-D-glucosaminyl-(1->4)-D-glucosamine

Names and Identifiers

Pubchem Sid 504768242
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504768242
IUPAC Name (2R,3S,4R,5R,6S)-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-2-(hydroxymethyl)oxane-3,4-diol
INCHI InChI=1S/C12H24N2O9/c13-5-9(19)10(4(2-16)21-11(5)20)23-12-6(14)8(18)7(17)3(1-15)22-12/h3-12,15-20H,1-2,13-14H2/t3-,4-,5-,6-,7-,8-,9-,10-,11-,12+/m1/s1
InChIKey QLTSDROPCWIKKY-PMCTYKHCSA-N
Smiles C(C1C(C(C(C(O1)OC2C(OC(C(C2O)N)O)CO)N)O)O)O
Isomeric SMILES C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)N)O)CO)N)O)O)O
Reaxy-Rn 25642292
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25642292&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

19 results found

Lot Number Certificate Type Date Item
F2526020 Certificate of Analysis May 06, 2025 C406214
E2521201 Certificate of Analysis May 06, 2025 C406214
E2521202 Certificate of Analysis May 06, 2025 C406214
C2518501 Certificate of Analysis Oct 23, 2024 C406214
J2425434 Certificate of Analysis Oct 21, 2024 C406214
J2425435 Certificate of Analysis Oct 21, 2024 C406214
H2405543 Certificate of Analysis Jul 27, 2024 C406214
H2405544 Certificate of Analysis Jul 27, 2024 C406214
A2419274 Certificate of Analysis Jan 08, 2024 C406214
A2419275 Certificate of Analysis Jan 08, 2024 C406214
A2419276 Certificate of Analysis Jan 08, 2024 C406214
H2323783 Certificate of Analysis Aug 08, 2023 C406214
H2323605 Certificate of Analysis Aug 08, 2023 C406214
H2323611 Certificate of Analysis Aug 08, 2023 C406214
L2321174 Certificate of Analysis Aug 08, 2023 C406214
G2214158 Certificate of Analysis Jul 03, 2022 C406214
F2314239 Certificate of Analysis Jul 03, 2022 C406214
H2303080 Certificate of Analysis Jul 03, 2022 C406214
G2214159 Certificate of Analysis Jul 03, 2022 C406214

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Chemical and Physical Properties

Solubility Soluble in water
Molecular Weight 340.330 g/mol
XLogP3 -5.200
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 4
Exact Mass 340.148 Da
Monoisotopic Mass 340.148 Da
Topological Polar Surface Area 201.000 Ų
Heavy Atom Count 23
Formal Charge 0
Complexity 390.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 10
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Jinhui Tang, Guangye Tu, Zongshuo Tao, Yu Yan.  (2023)  New Insights into the Dissolution Kinetics of Alite Powder and the Effects of Organic Toughening Materials.  Materials,  16  (22): (7242). 
2. Hongmei Yu, Yuanrong Zheng, Changyu Zhou, Lianliang Liu, Libin Wang, Jinxuan Cao, Yangyin Sun, Jun He, Daodong Pan, Zhendong Cai, Qiang Xia.  (2024)  Tunability of Pickering particle features of whey protein isolate via remodeling partial unfolding during ultrasonication-assisted complexation with chitosan/chitooligosaccharide.  CARBOHYDRATE POLYMERS,  325  (121583). 
3. Pierre Dramou, Yiyang Sun, Xu Ni, Fangqi Wang, Hua He.  (2024)  In-depth descriptive investigation of composite sorbent based self-assembled magnetic halloysite nanotube-graphene oxide: Actual use case study for rutin.  APPLIED CLAY SCIENCE,  247  (107193). 
4. Rui Wang.  (2023)  Bi-layer graphite felt as the positive electrode for zinc-bromine flow batteries: Achieving efficient redox reaction and stable mass transport.  Journal of Energy Storage,  74  (109487). 
5. Kaibo Xu, Liqin Cao, Zhouyu Wang, Liu-ping Chen.  (2023)  Heparin-Mimetic Chitooligosaccharides-Based Monoliths Obtained from C/W Emulsions: Hemocompatibility and Toxin Removal Ability.  ACS Biomaterials Science & Engineering,  (10): (5610–5621). 
6. Li-wei Liu, Zheng-hao Ding, Ganggang Ren, Guang-di Wang, Xin Pan, Guo-hai Wei, Xiang Zhou, Zhi-bing Wu, Zhi-chao Jin, Yonggui Robin Chi, Song Yang.  (2023)  Inorganic Nanoparticles–Driven Self–Assembly of natural small molecules in water for constructing multifunctional nanocapsules against plant diseases.  CHEMICAL ENGINEERING JOURNAL,    (146041). 
7. Kaibo Xu, Liqin Cao.  (2023)  Sulfonated Hydrogel Formed via CO2-in-Water Emulsion: Potential in Antibiotic Removal.  Gels,  (9): (703). 
8. Mengqi Jia, Ruilin Lu, Caikun Liu, Xiaodong Zhou, Pengfei Li, Shiyong Zhang.  (2023)  In Situ Implantation of Chitosan Oligosaccharide-Doped Lipoic Acid Hydrogel Breaks the “Vicious Cycle” of Inflammation and Residual Tumor Cell for Postoperative Skin Cancer Therapy.  ACS Applied Materials & Interfaces,     
9. Zhe Luo, Yang Zhang.  (2022)  Construction of a Chitosan/ZnO-Based Light-Resistant Coating System to Protect Dyed Wood from Ultraviolet Irradiation via Layer-by-Layer Self-Assembly.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  23  (24): (15735). 
10. Xinlong Wang, Huahui Zeng, Xin Zhu, Duanjie Xu, Qikang Tian, Can Wang, Lingzhou Zhao, Junwei Zhao, Mingsan Miao, Xiangxiang Wu.  (2022)  TP-CSO: A Triptolide Prodrug for Pancreatic Cancer Treatment.  MOLECULES,  27  (12): (3686). 
11. Chun-Xia Zhang, Yu Wang, Xinhe Duan, Kai Chen, Hong-Wei Li, Yuqing Wu.  (2022)  Development of cytidine 5′-monophosphate-protected gold-nanoclusters to be a direct luminescent substrate via aggregation-induced emission enhancement for ratiometric determination of alkaline phosphatase and inhibitor evaluation.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  640  (128423). 
12. Liu Xiaoli, Xie Wancui, Yang Xihong, Zhan Xiaobei, Xia Wenshui.  (2020)  Antimicrobial Polymer with Enhanced Activity and Reduced Toxicity upon Grafting to Chitosan Oligosaccharide.  ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING,  45  (1): (29-40). 
13. Wen Li, Qi-Wen Chen, Jin-Xuan Fan, Zi-Yi Han, Wen-Fang Song, Xuan Zeng, Xian-Zheng Zhang.  (2024)  Bacterial Biohybrids for Invasion of Tumor Cells Promote Antigen Cross-Presentation Through Gap Junction.  ADVANCED MATERIALS,    (2402532). 
14. Shujie Cheng, Shimin Wu, Jianqiang Lan.  (2024)  Beta-carotene and astaxanthin inhibit the formation of polycyclic aromatic hydrocarbons and oxygenated polycyclic aromatic hydrocarbons in butter during heat treatment.  INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY,     
15. Zhimin Deng, Hua Liu, Gantao Chen, Hongbing Deng, Xiangyang Dong, Linlin Wang, Fenghua Tao, Fangfang Dai, Yanxiang Cheng.  (2024)  Coaxial nanofibrous aerogel featuring porous network-structured channels for ovarian cancer treatment by sustained release of chitosan oligosaccharide.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  276  (133824). 
16. Wenshang Guo, Ye Tao, Ruizhe Yang, Kaihao Mao, Hongwei Zhou, Minghui Xu, Tie Sun, Xiao Li, Changrui Shi, Zhenyou Ge, Rui Xue, Haizhou Zhou, Yukun Ren.  (2024)  Compact highly sensitive photothermal RT-LAMP chip for simultaneous multidisease detection.  Science Advances,  10  (46): (2024 Nov;10(46)). 
17. Nanqi Zhao, Chaofan Guo, Ziyao Liu, Lin Chen, Yayun Hu, Minyi Han, Feng Huang, Zhuangli Kang, Xianchao Feng.  (2024)  Effects of different hydrocolloids on the 3D printing and thermal stability of chicken paste.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  277  (134006). 
18. Kangshuai Lou, Yuanrong Zheng, Hongmei Yu, Xiaohan Tan, Libin Wang, Changmin Tong, Siqiang Huang, Xintong Cai, Changyu Zhou, Jinxuan Cao, Daodong Pan, Zhen Wu, Hao Zhang, Qiang Xia.  (2025)  Influence of whey protein isolate-chitosan oligosaccharide micro gel pickering emulsion on reducing fat bioaccessibility and physicochemical features of cheddar cheese.  Food Bioscience,  63  (105771). 
19. Xiaokang Na, Bowen Zou, Xiaohan Zheng, Xueer Yu, Ling Zhang, Xianbing Xu, Ming Du, Chao Wu.  (2024)  One-step spraying of protein-anchored chitosan oligosaccharide antimicrobial coating for food preservation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  275  (133330). 
20. Hongmei Yu, Yuanrong Zheng, Kangshuai Lou, Changyu Zhou, Jinxuan Cao, Lihui Du, Yangying Sun, Jun He, Daodong Pan, Zhendong Cai, Qiang Xia.  (2024)  Proposing moderate unfolding of interfacial proteins to enhance the techno-functional features of complex microgel particles formed by whey protein-chitooligosaccharide conjugation.  FOOD HYDROCOLLOIDS,  156  (110329). 
21. Zhaoxin Xia, Yulong Liao, Ge Gao, Shiyong Zhang.  (2024)  Rifampicin-Loaded Polyelectrolyte Complex Eliminates Intracellular Bacteria through Thiol-Mediated Cellular Uptake and Oxidative Stress Enhancement.  ACS Applied Bio Materials,  (4): (2544-2553). 

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