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CAY10574 - ≥95%, high purity , CAS No.140651-18-9

COA

Grade & Purity:

≥95%

Cas Number: 140651-18-9
Molecular Weight: 218.22
PubChem CID: 135398514

In stock

Item Number

C275369

Grouped product items
SKU	Size	Availability	Price
C275369-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$38.90
C275369-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$90.90
C275369-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$180.90
C275369-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$755.90

Potent, selective Cdk9 kinase inhibitor

View related series

Cell Cycle (2830)

Basic Description

Synonyms	SCHEMBL922292 \| trans-4-Methoxycinnamate \| Caswell No. 541 \| Phenol, 4-(2-(3,5-diamino-1H-pyrazol-4-yl)diazenyl)- \| CAN 508 \| CHEBI:42356 \| 4-(3,5-Diamino-1H-pyrazol-4-ylazo)-phenol \| 5-phenyl-4h-1,2,4-triazol-3-ylhydrosulfide \| BDBM12028 \| 3,5-diamino-4-
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Potent, selective Cdk9 kinase inhibitor (IC 50 = 350 nM). Moderate ATP-competitive Cdk2-cyclin E inhibitor (IC 50 = 20 µM). Induces cell cycle arrest, decreasing S-phase.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Phenols
    - Subclass 1-hydroxy-2-unsubstituted benzenoids

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Phenols
Subclass	1-hydroxy-2-unsubstituted benzenoids
Intermediate Tree Nodes	Not available
Direct Parent	1-hydroxy-2-unsubstituted benzenoids
Alternative Parents	Imidolactams Benzene and substituted derivatives Pyrazoles Heteroaromatic compounds Azo compounds Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Primary amines Organooxygen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - Imidolactam - Azole - Heteroaromatic compound - Pyrazole - Azo compound - Azacycle - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Primary amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Amine - Organic nitrogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as 1-hydroxy-2-unsubstituted benzenoids. These are phenols that a unsubstituted at the 2-position.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol
INCHI	InChI=1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,16H,(H5,10,11,14,15)
InChIKey	AYZRKFOEZQBUEA-UHFFFAOYSA-N
Smiles	C1=CC(=CC=C1N=NC2=C(NN=C2N)N)O
Isomeric SMILES	C1=CC(=CC=C1N=NC2=C(NN=C2N)N)O
Molecular Weight	218.22
Reaxy-Rn	22629665
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22629665&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Soluble in DMSO
Molecular Weight	218.220 g/mol
XLogP3	0.900
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	218.092 Da
Monoisotopic Mass	218.092 Da
Topological Polar Surface Area	126.000 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	252.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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