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PI3K/Akt/mTOR
PI3K
CAY10505 - 97%, high purity , CAS No.1218777-13-9

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CAY10505 - 97%, high purity , CAS No.1218777-13-9

COA

Grade & Purity:

≥97%

Cas Number: 1218777-13-9
Molecular Weight: 289.28
PubChem CID: 1204893
PubChem SID: 504760415

In stock

Item Number

C129600

Grouped product items
SKU	Size	Availability	Price
C129600-5mg	5mg	3	$29.90
C129600-10mg	10mg	3	$48.90
C129600-25mg	25mg	2	$88.90
C129600-50mg	50mg	2	$147.90
C129600-100mg	100mg	2	$226.90
C129600-250mg	250mg	2	$510.90

View related series

Apoptosis (4276) PI3K (243) PI3K/Akt/mTOR (765)

Basic Description

Synonyms	J-004691 \| 5-((5-(4-Fluorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione \| AB00083720-01 \| AKOS000409173 \| SW113275-2 \| 2,4-Thiazolidinedione, 5-[[5-(4-fluorophenyl)-2-furanyl]methylene]- \| DTXSID60360955 \| (E)-5-((5-(4-fluorophenyl)furan-2-yl)methyle
Specifications & Purity	≥97%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Azolidines
    - Subclass Thiazolidines
      - Level5 Thiazolidinones
        Level6 Thiazolidinediones

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Azolidines
Subclass	Thiazolidines
Intermediate Tree Nodes	Thiazolidinones
Direct Parent	Thiazolidinediones
Alternative Parents	Fluorobenzenes Aryl fluorides Heteroaromatic compounds Furans Dicarboximides Thiocarbamic acid derivatives Organic carbonic acids and derivatives Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Fluorobenzene - Halobenzene - Thiazolidinedione - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Dicarboximide - Heteroaromatic compound - Furan - Thiocarbamic acid derivative - Carbonic acid derivative - Carboxylic acid derivative - Oxacycle - Azacycle - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as thiazolidinediones. These are heterocyclic compounds containing a thiazolidine ring which bears two ketone groups.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

INSR Tclin Insulin receptor (5558 Activities)

Discover Target: INSR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IGF1R Tclin Insulin-like growth factor I receptor (8605 Activities)

Discover Target: IGF1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504760415
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504760415
IUPAC Name	(5E)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione
INCHI	InChI=1S/C14H8FNO3S/c15-9-3-1-8(2-4-9)11-6-5-10(19-11)7-12-13(17)16-14(18)20-12/h1-7H,(H,16,17,18)/b12-7+
InChIKey	UFBTYTGRUBUUIL-KPKJPENVSA-N
Smiles	C1=CC(=CC=C1C2=CC=C(O2)C=C3C(=O)NC(=O)S3)F
Isomeric SMILES	C1=CC(=CC=C1C2=CC=C(O2)/C=C/3\C(=O)NC(=O)S3)F
Molecular Weight	289.28
Reaxy-Rn	33160874
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33160874&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
L2418074	Certificate of Analysis	Dec 27, 2024	C129600
K2110492	Certificate of Analysis	Aug 15, 2023	C129600
K2110477	Certificate of Analysis	Aug 15, 2023	C129600
K2110476	Certificate of Analysis	Aug 15, 2023	C129600
K2111113	Certificate of Analysis	Aug 15, 2023	C129600
K2111114	Certificate of Analysis	Aug 15, 2023	C129600
K2110475	Certificate of Analysis	Aug 15, 2023	C129600

Chemical and Physical Properties

Solubility	DMSO 58 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
Molecular Weight	289.280 g/mol
XLogP3	3.100
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	289.021 Da
Monoisotopic Mass	289.021 Da
Topological Polar Surface Area	84.600 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	446.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

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