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Cathepsin S Inhibitor Screening Kit - Sufficient for 100 Fluorometric tests, high purity

    Grade & Purity:
  • Sufficient for 100 Fluorometric tests
In stock
Item Number
C486429
Grouped product items
SKU Size
Availability
Price Qty
C486429-1kit
1kit
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,510.90

Basic Description

Synonyms CTSS Inhibitor Assay Kit
Specifications & Purity Sufficient for 100 Fluorometric tests
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Description

Cathepsin S (CTSS; EC 3.4.22.27) is a lysosomal cysteine proteinase involved in the degradation of proteins to peptides required for the presentation of MHC class II molecules.1 It is associated with pathological conditions such as atherosclerosis, coronary heart disease, cancer, and insulin resistance.Suitability: Suitable for the screening of inhibitors of Cathepsin S.Principle: The Cathepsin S Inhibitor Screening Kit is a simple assay for screening potential inhibitors of CTSS. CTSS activity is measured by cleaving a synthetic 7-amino-4-trifluoromethylcoumarin (AFC)-based substrate to yield AFC, a fluorescent product (λex= 400/ λem= 505 nm), proportional to the enzymatic activity present.}


Preparation instructions



Principle

The Cathepsin S Inhibitor Screening Kit is a simple assay for screening potential inhibitors of CTSS. CTSS activity is measured by cleaving a synthetic 7-amino-4-trifluoromethylcoumarin (AFC)-based substrate to yield AFC, a fluorescent product (λ\

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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