Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
C422711-1ml
|
1ml |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$94.90
|
|
| Synonyms | (+)-Catechin Hydrate | Catechin hydrate | 225937-10-0 | (+)-catechin monohydrate | 88191-48-4 | (2R,3S)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol hydrate | (+)-Cyanidol-3 | CHEBI:58994 | (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol monohydr |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | An antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems. For example, at physiological pH catechin suppressed DNA strand breaks by hydroxyl radicals. It has also been s |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
(+)-Catechin monohydrate is an antioxidant flavonoid that is a free radical scavenger. Research shows that it is relatively nontoxic to cells at high doses. (+)-Catechin can stop ultraviolet B induced human keratinocyte death through the inhibition of JNK phosphorylation. Literature indicates that it may have Ca2+ antagonistic activity. (+)-Catechin monohydrate is an inhibitor of Cox-1. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Flavonoids |
| Subclass | Flavans |
| Intermediate Tree Nodes | Flavan-3-ols |
| Direct Parent | Catechins |
| Alternative Parents | 3'-hydroxyflavonoids 3-hydroxyflavonoids 4'-hydroxyflavonoids 5-hydroxyflavonoids 7-hydroxyflavonoids 1-benzopyrans Catechols 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Alkyl aryl ethers Benzene and substituted derivatives Secondary alcohols Oxacyclic compounds Polyols Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Catechin - Hydroxyflavonoid - 7-hydroxyflavonoid - 5-hydroxyflavonoid - 4'-hydroxyflavonoid - 3-hydroxyflavonoid - 3'-hydroxyflavonoid - 1-benzopyran - Chromane - Benzopyran - Catechol - Alkyl aryl ether - Phenol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Monocyclic benzene moiety - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Polyol - Ether - Alcohol - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as catechins. These are compounds containing a catechin moiety, which is a 3,4-dihydro-2-chromene-3,5.7-tiol. |
| External Descriptors | hydrate |
|
|
|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate |
|---|---|
| INCHI | InChI=1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1 |
| InChIKey | OFUMQWOJBVNKLR-NQQJLSKUSA-N |
| Smiles | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O.O |
| Isomeric SMILES | C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O.O |
| WGK Germany | 3 |
| RTECS | DJ3450000 |
| Alternate CAS | 154-23-4 |
| Molecular Weight | 290.27 |
| Beilstein | 3595244 |
| Reaxy-Rn | 31285846 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31285846&ln= |
| Melt Point(°C) | 96°C(lit.) |
|---|---|
| Molecular Weight | 308.280 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 1 |
| Exact Mass | 308.09 Da |
| Monoisotopic Mass | 308.09 Da |
| Topological Polar Surface Area | 111.000 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 364.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
| 1. Zijian Liang, Pangzhen Zhang, Wen Ma, Xin-An Zeng, Zhongxiang Fang. (2024) Physicochemical properties, antioxidant activities and comprehensive phenolic profiles of tea-macerated Chardonnay wine and model wine. FOOD CHEMISTRY, 436 (137748). |
| 2. Tong Jiang, Hong Wang, Peihua Xu, Yifan Yao, Yilong Ma, Zhaojun Wei, Xiangli Niu, Yafang Shang, Dong Zhao. (2023) Effect of grape seed proanthocyanidin on the structural and physicochemical properties of bread during bread fermentation stage. Current Research in Food Science, 7 (100559). |
| 3. Mao-Ling Luo, Hua Chen, Guo-Ying Chen, Shengpeng Wang, Yitao Wang, Feng-Qing Yang. (2023) Preparation of Alcohol Dehydrogenase–Zinc Phosphate Hybrid Nanoflowers through Biomimetic Mineralization and Its Application in the Inhibitor Screening. MOLECULES, 28 (14): (5429). |
| 4. Chengxiang Chu, Xianfeng Wang, Yuanyi Deng, Yi Ma, Chengyue Zou, Mei Yang, Huibo Luo, Danqun Huo, Changjun Hou. (2023) Discrimination of Chinese green tea according to tea polyphenols using fluorescence sensor array based on Tb (III) and Eu (III) doped Zr (IV) metal–organic frameworks. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 292 (122380). |
| 5. Shuai Zhang, Qin Ma, Lihong Dong, Xuchao Jia, Lei Liu, Fei Huang, Guang Liu, Zhida Sun, Jianwei Chi, Mingwei Zhang, Ruifen Zhang. (2022) Phenolic profiles and bioactivities of different milling fractions of rice bran from black rice. FOOD CHEMISTRY, 378 (132035). |
| 6. Yirong Xia, Xintong Wang, Hechen Sun, Ximing Huang. (2021) Proton-coupled electron transfer of catechin in tea wine: the enhanced mechanism of anti-oxidative capacity. RSC Advances, 11 (63): (39985-39993). |
| 7. Murtaza Ali, Jun-Hu Cheng, Da-Wen Sun. (2020) Effects of dielectric barrier discharge cold plasma treatments on degradation of anilazine fungicide and quality of tomato (Lycopersicon esculentum Mill) juice. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 56 (1): (69-75). |
| 8. Mengting Wang, Jinyuan Shi, Lei Wang, Yaqin Hu, Xingqian Ye, Donghong Liu, Jianchu Chen. (2018) Inhibitory kinetics and mechanism of flavonoids from lotus (Nelumbo nucifera Gaertn.) leaf against pancreatic α-amylase. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 120 (2589). |
| 9. Juan Xu, Hongpo Zhou, Kun Li, Jinju Ma, Wenwen Zhang, Lanxiang Liu, Yanlin Sun, Hong Zhang, Kai Li. (2018) Multi-scale pectin/polyphenol beads for non-fouling fluorescence tracking on soft matter under water. CARBOHYDRATE POLYMERS, 199 (186). |
| 10. Rana Muhammad Aadil, Xin-An Zeng, Zhong Han, Amna Sahar, Anees Ahmed Khalil, Ubaid Ur Rahman, Muneeb Khan, Tariq Mehmood. (2017) Combined effects of pulsed electric field and ultrasound on bioactive compounds and microbial quality of grapefruit juice. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 42 (2): (e13507). |
| 11. Dongwei Wei, Weizhi Huo, Guangmeng Li, Qiuling Xie, Yanbin Jiang. (2018) The combined effects of lysozyme and ascorbic acid on microstructure and properties of zein-based films. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 26 (648). |
| 12. Lite Yang, Bingjie Xu, Huili Ye, Faqiong Zhao, Baizhao Zeng. (2017) A novel quercetin electrochemical sensor based on molecularly imprinted poly(para-aminobenzoic acid) on 3D Pd nanoparticles-porous graphene-carbon nanotubes composite. SENSORS AND ACTUATORS B-CHEMICAL, 251 (601). |
| 13. Lele Zhang, Minglei Yang, Junlan Gao, Shan Jin, Zhengyan Wu, Lifang Wu, Xin Zhang. (2016) Seasonal variation and gender pattern of phenolic and flavonoid contents in Pistacia chinensis Bunge inflorescences and leaves. JOURNAL OF PLANT PHYSIOLOGY, 191 (36). |
| 14. Rana Muhammad Aadil, Xin-An Zeng, Amjad Ali, Feng Zeng, Muhammad Adil Farooq, Zhong Han, Saud Khalid, Saqib Jabbar. (2015) Influence of different pulsed electric field strengths on the quality of the grapefruit juice. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 50 (10): (2290-2296). |
| 15. Rana Muhammad Aadil, Xin-An Zeng, Man-Sheng Wang, Zhi-Wei Liu, Zhong Han, Zhi-Hong Zhang, Jing Hong, Saqib Jabbar. (2015) A potential of ultrasound on minerals, micro-organisms, phenolic compounds and colouring pigments of grapefruit juice. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 50 (5): (1144-1150). |
| 16. Rana Muhammad Aadil, Xin-An Zeng, Zhi-Hong Zhang, Man-Sheng Wang, Zhong Han, Hong Jing, Saqib Jabbar. (2015) Thermosonication: a potential technique that influences the quality of grapefruit juice. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 50 (5): (1275-1282). |
| 17. Yurong Ma, Huihua Huang. (2014) Characterisation and comparison of phenols, flavonoids and isoflavones of soymilk and their correlations with antioxidant activity. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 49 (10): (2290-2298). |
| 18. Mengying He, Ting Wu, Siyi Pan, Xiaoyun Xu. (2014) Antimicrobial mechanism of flavonoids against Escherichia coli ATCC 25922 by model membrane study. APPLIED SURFACE SCIENCE, 305 (515). |
| 19. Huijie Zhang, Mingqin Kang, Hanqi Zhang, Yong Yu. (2014) Matrix solid phase dispersion extraction for determination of flavonoids in the flower of Chrysanthemum morifolium Ramat. by capillary zone electrophoresis. Analytical Methods, 6 (3): (766-773). |
| 20. Obafemi Ibitayo Obajemihi, Jun-Hu Cheng, Da-Wen Sun. (2024) Enhancing Moisture Transfer and Quality Attributes of Tomato Slices Through Synergistic Cold Plasma and Osmodehydration Pretreatments During Infrared-Assisted Pulsed Vacuum Drying. JOURNAL OF FOOD ENGINEERING, (112335). |
| 21. Obafemi Ibitayo Obajemihi, Jun-Hu Cheng, Da-Wen Sun. (2024) Novel cold plasma functionalized water pretreatment for improving drying performance and physicochemical properties of tomato (Solanum lycopersicum L.) fruits during infrared-accelerated pulsed vacuum drying. JOURNAL OF FOOD ENGINEERING, (112050). |
| 22. Liang Zijian, Zhang Pangzhen, Ma Wen, Zeng Xin-An, Fang Zhongxiang. (2024) Quality attributes of black tea-flavored Chardonnay wine processed by ultrasound. Food Production Processing and Nutrition, 6 (1): (1-15). |