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(-)-Catechin Gallate - ≥98% (HPLC), high purity , CAS No.130405-40-2

13 Citations COA COA
    Grade & Purity:
  • ≥98%(HPLC)
In stock
Item Number
C131962
Grouped product items
SKU Size
Availability
 Price Qty
C131962-1mg
1mg
3
$136.90
C131962-5mg
5mg
3
$301.90
C131962-10mg
10mg
2
$486.90
C131962-25mg
25mg
3
$1,095.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet
View related series
COX (258) Immunology/Inflammation (1929)

Basic Description

Synonyms (?)-Catechin gallate | (-)-Catechin gallate | C22H18O10 | S00277 | (-)-Catechin gallate(CG) | (2S,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate | AC-34201 | ent-Catechin 3-O-gallate | Benzoic acid, 3,4,5-trihydroxy-, 2-(3,
Specifications & Purity ≥98%(HPLC)
Biochemical and Physiological Mechanisms Antioxidant constituent of green tea. At μM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cance
Storage Temp Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

(-) -catechin gallate is a microcomponent of green tea Catechin, which can inhibit the activities of COX-1 and COX-2. It inhibits human Beta-Secretase, and chloroquine-sensitive Plasmodium falciparum NF54 and chloroquine-resistant Plasmodium falciparum K1 have antiplasmodium activity.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Flavonoids
Subclass Flavans
Intermediate Tree Nodes Flavan-3-ols - Catechins
Direct Parent Catechin gallates
Alternative Parents 3'-hydroxyflavonoids  4'-hydroxyflavonoids  5-hydroxyflavonoids  7-hydroxyflavonoids  Galloyl esters  p-Hydroxybenzoic acid alkyl esters  m-Hydroxybenzoic acid esters  1-benzopyrans  Pyrogallols and derivatives  Benzoyl derivatives  Catechols  Alkyl aryl ethers  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Carboxylic acid esters  Polyols  Monocarboxylic acids and derivatives  Oxacyclic compounds  Hydrocarbon derivatives  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Catechin gallate - 3'-hydroxyflavonoid - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Hydroxyflavonoid - Galloyl ester - Gallic acid or derivatives - P-hydroxybenzoic acid alkyl ester - M-hydroxybenzoic acid ester - P-hydroxybenzoic acid ester - Benzoate ester - Chromane - Benzopyran - 1-benzopyran - Benzenetriol - Benzoic acid or derivatives - Pyrogallol derivative - Catechol - Benzoyl - Phenol - Alkyl aryl ether - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Monocyclic benzene moiety - Carboxylic acid ester - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Ether - Oxacycle - Organoheterocyclic compound - Polyol - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as catechin gallates. These are organic compounds containing a gallate moiety glycosidically linked to a catechin.
External Descriptors Flavans, Flavanols and Leucoanthocyanidins

Associated Targets(Human)

PSMB5 Tclin Proteasome subunit beta type-5 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FASN Tchem Fatty acid synthase (3390 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PGD Tchem 6-phosphogluconate dehydrogenase (58 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DYRK1A Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 1A (6484 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BACE1 Tchem Beta-secretase 1 (15641 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PSMB5 Tclin Proteasome Macropain subunit MB1 (2451 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
G6PD Tchem Glucose-6-phosphate 1-dehydrogenase (778 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fabG 3-oxoacyl-acyl-carrier protein reductase (70 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fabI Enoyl-acyl-carrier protein reductase (415 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name [(2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
INCHI InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21+/m1/s1
InChIKey LSHVYAFMTMFKBA-CTNGQTDRSA-N
Smiles C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Isomeric SMILES C1[C@H]([C@@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
WGK Germany 3
Molecular Weight 442.37
Reaxy-Rn 372029
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=372029&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number Certificate Type Date Item
D1811124 Certificate of Analysis Jul 09, 2025 C131962
D1811123 Certificate of Analysis Jul 09, 2025 C131962
F23251338 Certificate of Analysis May 15, 2025 C131962
F23251310 Certificate of Analysis Apr 07, 2025 C131962
F23251322 Certificate of Analysis Apr 07, 2025 C131962
F23251328 Certificate of Analysis Apr 07, 2025 C131962
K2120606 Certificate of Analysis Sep 18, 2023 C131962
K2120360 Certificate of Analysis Sep 18, 2023 C131962
K2120354 Certificate of Analysis Sep 18, 2023 C131962
F23251210 Certificate of Analysis May 31, 2023 C131962

Chemical and Physical Properties

Solubility DMSO : 100 mg/mL (226.06 mM)
Molecular Weight 442.400 g/mol
XLogP3 1.500
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 10
Rotatable Bond Count 4
Exact Mass 442.09 Da
Monoisotopic Mass 442.09 Da
Topological Polar Surface Area 177.000 Ų
Heavy Atom Count 32
Formal Charge 0
Complexity 649.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen.  (2023)  Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars.  Plants-Basel,  12  (21): (3707). 
2. Su Zhou, Jiaying Yang, Yani Pan, Xinyu Feng, Hao Hu, Shicheng Ma, Cansong Ou, Fangyuan Fan, Shuying Gong, Yuefei Wang, Ping Chen, Qiang Chu.  (2023)  Pu’ er raw tea extract alleviates DSS-induced colitis in mice by restoring intestinal barrier function and maintaining gut microbiota homeostasis.  Food Bioscience,  53  (102750). 
3. Wanglong Zhang, Yu Dai, Fan Xia, Xiaojin Zhang.  (2023)  Interfacial Molecular Lock: A Universal Strategy for Hydrogel Adhesion.  ACS Applied Polymer Materials,  5  (1): (1037–1045). 
4. Yu-Meng Zhu, Jun-Jie Dong, Jing Jin, Jin-Hua Liu, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye.  (2021)  Roasting process shaping the chemical profile of roasted green tea and the association with aroma features.  FOOD CHEMISTRY,  353  (129428). 
5. Dandan Qin, Qiushuang Wang, Hongjian Li, Xiaohui Jiang, Kaixing Fang, Qing Wang, Bo Li, Chendong Pan, Hualing Wu.  (2020)  Identification of key metabolites based on non-targeted metabolomics and chemometrics analyses provides insights into bitterness in Kucha [Camellia kucha (Chang et Wang) Chang].  FOOD RESEARCH INTERNATIONAL,  138  (109789). 
6. Meng Shi, Ying Nie, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye.  (2016)  Ultraviolet B (UVB) Photosensitivities of Tea Catechins and the Relevant Chemical Conversions.  MOLECULES,  21  (10): (1345). 
7. Fang-Yuan Fan, Meng Shi, Ying Nie, Yue Zhao, Jian-Hui Ye, Yue-Rong Liang.  (2016)  Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers.  FOOD CHEMISTRY,  196  (347). 
8. Yueming Liang, Zhusheng Liu, Yuelan Pang, Min Li, Shengmeng Zheng, Fujing Pan, Chunyu Guo, Qianhua Wu, Ting Chen, Qiang Li, Zhonghua Liu.  (2024)  Effects of storage durations on flavour and bacterial communities in Liupao tea.  FOOD CHEMISTRY,    (142697). 
9. Yan Hu, Wei Chen, Mostafa Gouda, Huan Yao, Xinxin Zuo, Huahao Yu, Yuying Zhang, Lejia Ding, Fengle Zhu, Yuefei Wang, Xiaoli Li, Jihong Zhou, Yong He.  (2024)  Fungal fermentation of Fuzhuan brick tea: A comprehensive evaluation of sensory properties using chemometrics, visible near-infrared spectroscopy, and electronic nose.  FOOD RESEARCH INTERNATIONAL,  186  (114401). 
10. Huan Fang, Tong Wang, Lan Chen, Xiao-Zhi Wang, Hai-Long Wu, Yao Chen, Ru-Qin Yu.  (2024)  Rapid authenticity identification of high-quality Wuyi Rock tea by multidimensional fluorescence spectroscopy coupled with chemometrics.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  135  (106632). 
11. Yating Guo, Yani Pan, Xinyu Feng, Haowei Guo, Liping Liu, Kexin Zhang, Haojun Xie, Binkai Zhu, Shuying Gong, Qiang Chu, Hua Fang, Ping Chen.  (2025)  Reshaped local microbiology metabolism by raw tea according to pile fermentation in the dark tea.  Journal of Advanced Research,     
12. Haozhen Li, Shuyao Wang, Xiaohua Zhang, Kangkang Song, Long Yang.  (2025)  Revealing novel insights into the improvement of greenhouse tea quality through exogenous substance interventions using targeted and untargeted metabolomics and microbial community analyses.  Food Chemistry-X,  27  (102410). 
13. Lan Zhang, Haocun Kong, Bimal Chitrakar, Xiaofeng Ban, Zhengbiao Gu, Yan Hong, Li Cheng, Zhaofeng Li, Caiming Li.  (2024)  The substitution sites of hydroxyl and galloyl groups determine the inhibitory activity of human pancreatic α-amylase in twelve tea polyphenol monomers.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  259  (129189). 

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