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Search results for: '727'

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  1. , Inhibitor of bromodomain containing 9
    BI-7273, Inhibitor of bromodomain containing 9
    Cas Number:  1883429-21-7
    Formula:  C20H23N3O3
    Molecular weight:  353.41
    Synonyms:  2,​7-​Naphthyridin-​1(2H)​-​one,4-​[4-​[(dimethylamino)​methyl]​-​3,​5-​dime...
    SMILES:  CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)C)OC
    InChIKey:  RBUYFHLQNPJMQM-UHFFFAOYSA-N
    InChI:  InChI=1S/C20H23N3O3/c1-22(2)11-17-18(25-4)8-13(9-19(17)26-5)16-12-23(3)20(24)15-10-21-7-6-14(15)16/h6-10,12H,11H2,1-5H3
  2. , Inhibitor of bromodomain containing 9
    BI-7273, Inhibitor of bromodomain containing 9
    SMILES:  COc1cc(cc(c1CN(C)C)OC)c1cn(C)c(=O)c2c1ccnc2
    InChIKey:  RBUYFHLQNPJMQM-UHFFFAOYSA-N
    InChI:  InChI=1S/C20H23N3O3/c1-22(2)11-17-18(25-4)8-13(9-19(17)26-5)16-12-23(3)20(24)15-10-21-7-6-14(15)16/h6-10,12H,11H2,1-5H3
  3. , Antibody of proprotein convertase subtilisin/kexin type 9
    Alirocumab (anti-PCSK9), Antibody of proprotein convertase subtilisin/kexin type 9
    Cas Number:  1245916-14-6
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PCSK9
    Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
    Host species: Human    Conjugation: Unconjugated    
    Synonyms:  Recombinant Alirocumab Antibody | REGN 727 | SAR 236553 | Alirocumab (anti-PCSK9) | Anti-PCSK9 Refer...
    SMILES:  C(C(COP(=O)(O)O)O)O.[Na].[Na]
    InChIKey:  CATWCRUATKKAAQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;
  4. , Inhibitor of complement factor D
    1-[2-[(1R,3S,5R)-3-[(6-bromopyridin-2-yl)carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxoethyl]indazole-3-carboxamide, Inhibitor of complement factor D
    Synonyms:  example 727 [WO2012093101A1] | compound 2
    SMILES:  Brc1cccc(n1)NC(=O)[C@@H]1C[C@@H]2[C@H](N1C(=O)Cn1nc(c3c1cccc3)C(=O)N)C2
    InChIKey:  CWZUTHDJLNZLCM-DFBGVHRSSA-N
    InChI:  InChI=1S/C21H19BrN6O3/c22-16-6-3-7-17(24-16)25-21(31)15-9-11-8-14(11)28(15)18(29)10-27-13-5-2-1-4-12(13)19(26-27)20(23)30/h1-7,11,14-15H,8-10H2,(H2,23,30)(H,24,25,31)/t11-,14-,15+/m1/s1
  5. Heptafluoronaphthalen-2-ol
    Cas Number:  727-49-1
    Formula:  C10HF7O
    Molecular weight:  270.1
    Synonyms:  727-49-1|1,3,4,5,6,7,8-heptafluoronaphthalen-2-ol|Heptafluoro-2-naphthol|heptafluoronaphthalen-2-ol|...
    SMILES:  C12=C(C(=C(C(=C1F)O)F)F)C(=C(C(=C2F)F)F)F
    InChIKey:  RWEQEWKAJFTONV-UHFFFAOYSA-N
    InChI:  InChI=1S/C10HF7O/c11-3-1-2(4(12)8(16)7(3)15)6(14)10(18)9(17)5(1)13/h18H
  6. Copper(II) methacrylate
    Cas Number:  19662-59-0
    Formula:  C8H10CuO4
    Molecular weight:  233.71
    Synonyms:  Copper(2+) methacrylate | copper;2-methylprop-2-enoate | EINECS 243-211-5 | VZWHXRLOECMQDD-UHFFFAOYS...
    SMILES:  CC(=C)C(=O)[O-].CC(=C)C(=O)[O-].[Cu+2]
    InChIKey:  VZWHXRLOECMQDD-UHFFFAOYSA-L
    InChI:  InChI=1S/2C4H6O2.Cu/c2*1-3(2)4(5)6;/h2*1H2,2H3,(H,5,6);/q;;+2/p-2
  7. 4-Methylthio-4-methyl-2-pentanone
    Cas Number:  23550-40-5       EC Number: 245-727-6
    Formula:  C7H14OS
    Molecular weight:  146.25
    Synonyms:  D95281 | FEMA 3376 | Q-100302 | 4-methyl-4-(methylsulfanyl)pentan-2-one | EINECS 245-727-6 | 2-Penta...
    SMILES:  CC(=O)CC(C)(C)SC
    InChIKey:  DHANVOSHQILVNQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C7H14OS/c1-6(8)5-7(2,3)9-4/h5H2,1-4H3
  8. 2-Fluoroadenosine
    Cas Number:  146-78-1
    Formula:  C10H12FN5O4
    Molecular weight:  285.23
    Synonyms:  SRI 727 | 2FA | ADENOSINE, 2-FLUORO- | MFCD00866394 | 2-Fluoroadenosine, 97% | AI3-52599 | NCGC00181...
    SMILES:  C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N
    InChIKey:  HBUBKKRHXORPQB-UUOKFMHZSA-N
    InChI:  InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
  9. Recombinant Human GFR alpha-2/GFRA2 Protein
    Short Overview:  Animal Free, ≥95% (SDS-PAGE), Active, HEK293, C-His tag, 22-441 aa
    Species: Human    Accession #: O00451-1    
    Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
    Bioactivity: Immobilized Recombinant Human Neurturin Protein at 5.0 μg/mL can bind Recombinant Human GFR alpha-2/GFRA2 Protein (rp146403), the EC50 of this effect is 1.99 μg/mL.    
    Synonyms:  GDNF family receptor alpha 2 | GDNF family receptor alpha-2 | GDNF receptor alpha-2 | GDNF receptor ...
  10. HP590
    Formula:  C29H24F6N4O3
    Molecular weight:  590.52
    SMILES:  O=C(N1CCN(CC1)CC2=CC=C(C=C2)OCC(F)(F)F)C3=CC=C(C=C3)C4=NC(C5=CC=C(C=C5)C(F)(F)F)=NO4
  11. Recombinant Human Tie-2 Protein
    Short Overview:  Animal Free, ≥95% (SDS-PAGE), 293F cell, C-His tag, 1-745 aa
    Species: Human    Accession #: Q02763    
    Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
    Bioactivity: Testing in progress    
    Synonyms:  CD202b antigen | CD202b | EC 2.7.10 | EC 2.7.10.1 | hTIE2 | p140 TEK | soluble TIE2 variant 1 | solu...
  12. Recombinant Caveolin-2 Antibody
      Application:
    • IF/ICC
    • IHC
    • WB
    Associated targets:  CAV2
    Short Overview: Recombinant; Rabbit anti Human Caveolin-2 Antibody; WB, IHC, ICC, IF; Unconjugated    
    Species reactivity（Reacts with): Human    Isotype: Rabbit IgG    
    Host species: Rabbit    Conjugation: Unconjugated    
    Synonyms:  CAV antibody | CAV2 antibody | CAV2_HUMAN antibody | Caveolae protein 20 kD antibody | Caveolin 2 an...
  13. Tetrapropylammonium bromide
    56 Citations
    Cas Number:  1941-30-6       EC Number: 217-727-6
    Formula:  C12H28NBr
    Molecular weight:  266.27
    Synonyms:  Tetrapropylammonium bromide|1941-30-6|tetra-n-Propylammonium bromide|1-Propanaminium, N,N,N-tripropy...
    SMILES:  CCC[N+](CCC)(CCC)CCC.[Br-]
    InChIKey:  BGQMOFGZRJUORO-UHFFFAOYSA-M
    InChI:  InChI=1S/C12H28N.BrH/c1-5-9-13(10-6-2,11-7-3)12-8-4;/h5-12H2,1-4H3;1H/q+1;/p-1
  14. 2-Chloro-4-(trifluoromethyl)benzo[d]thiazole
    Cas Number:  898748-15-7       EC Number: 872-727-9
    SMILES:  C1=CC(=C2C(=C1)SC(=N2)Cl)C(F)(F)F
    InChIKey:  MTDGCBQYEPMXDI-UHFFFAOYSA-N
    InChI:  InChI=1S/C8H3ClF3NS/c9-7-13-6-4(8(10,11)12)2-1-3-5(6)14-7/h1-3H
  15. 2-(Trifluoromethyl)benzophenone
    Cas Number:  727-99-1
    Formula:  C14H9F3O
    Molecular weight:  250.22
    Synonyms:  Q63409207 | 2-TRIFLUOROMETHYLBENZOPHENONE | 2-trifluoromethyl-benzophenone | Methanone, phenyl[2-(tr...
    SMILES:  C1=CC=C(C=C1)C(=O)C2=CC=CC=C2C(F)(F)F
    InChIKey:  JXIWJBWMQXDALU-UHFFFAOYSA-N
    InChI:  InChI=1S/C14H9F3O/c15-14(16,17)12-9-5-4-8-11(12)13(18)10-6-2-1-3-7-10/h1-9H
  16. Salicylanilide
    Cas Number:  87-17-2       EC Number: 201-727-8
    Formula:  C13H11NO2
    Molecular weight:  213.23
    Synonyms:  Pharmakon1600-00300618 | Anilid kyseliny salicylove [Czech] | Salifebrin | CHEBI:239133 | HY-B1408 |...
    SMILES:  C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O
    InChIKey:  WKEDVNSFRWHDNR-UHFFFAOYSA-N
    InChI:  InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16)
  17. Gefurulimab (anti-C5&Albumin)
    Cas Number:  2456407-94-4
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  C5 ALB
    Short Overview: Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Human    
    Conjugation: Unconjugated    
    Synonyms:  Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein ...
    SMILES:  [Gefurulimab]
  18. Coenzyme Q₁
    Cas Number:  727-81-1
    Formula:  C14H18O4
    Molecular weight:  250.29
    Synonyms:  CoQ1 | CO-Q1 | 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone | DB08689 | Ubiquinone...
    SMILES:  CC1=C(C(=O)C(=C(C1=O)OC)OC)CC=C(C)C
    InChIKey:  SOECUQMRSRVZQQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3
  19. , Inhibitor of lanosterol synthase
    ethyl(3-phenylprop-2-yn-1-yl)[(3-{[4-(thiophen-3-yl)thiophen-2-yl]methoxy}phenyl)methyl]amine, Inhibitor of lanosterol synthase
    Synonyms:  compound 1
    SMILES:  CCN(Cc1cccc(c1)OCc1scc(c1)c1cscc1)CC#Cc1ccccc1
    InChIKey:  GZVZWBOHPHLQFU-UHFFFAOYSA-N
    InChI:  InChI=1S/C27H25NOS2/c1-2-28(14-7-11-22-8-4-3-5-9-22)18-23-10-6-12-26(16-23)29-19-27-17-25(21-31-27)24-13-15-30-20-24/h3-6,8-10,12-13,15-17,20-21H,2,14,18-19H2,1H3
  20. , Inhibitor of squalene synthase
    4-{[3-({[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](ethyl)amino}methyl)phenoxymethyl]dimethylsilyl}benzonitrile, Inhibitor of squalene synthase
    Synonyms:  compound 4q
    SMILES:  CCN(Cc1cccc(c1)OC[Si](c1ccc(cc1)C#N)(C)C)C/C=C/C#CC(C)(C)C
    InChIKey:  LIDUGWDLSDKCLM-CSKARUKUSA-N
    InChI:  InChI=1S/C28H36N2OSi/c1-7-30(19-10-8-9-18-28(2,3)4)22-25-12-11-13-26(20-25)31-23-32(5,6)27-16-14-24(21-29)15-17-27/h8,10-17,20H,7,19,22-23H2,1-6H3/b10-8+
  21. 2-chloro-3-hydrazinylpyrazine
    Cas Number:  63286-28-2       EC Number: 640-727-6
    Formula:  C4H5ClN4
    Molecular weight:  144.56
    Synonyms:  DTXSID00313546 | AKOS005745086 | SY031007 | 3-chloro-2-hydrazinopyrazine | (3-chloropyrazin-2-yl)hyd...
    SMILES:  C1=CN=C(C(=N1)NN)Cl
    InChIKey:  PUUGNIKJWZNTBK-UHFFFAOYSA-N
    InChI:  InChI=1S/C4H5ClN4/c5-3-4(9-6)8-2-1-7-3/h1-2H,6H2,(H,8,9)
  22. Isobornyl acetate
    2 Citations
    Cas Number:  125-12-2       EC Number: 204-727-6
    Formula:  C12H20O2
    Molecular weight:  196.29
    Synonyms:  2-Camphanyl acetate | DTXSID7042061 | NCGC00257423-01 | AKOS006281613 | HY-N2583 | ( not+/-)-Isoborn...
    SMILES:  CC(=O)OC1CC2CCC1(C2(C)C)C
    InChIKey:  KGEKLUUHTZCSIP-JBLDHEPKSA-N
    InChI:  InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10,4)11(9,2)3/h9-10H,5-7H2,1-4H3/t9-,10-,12+/m0/s1
  23. (S)-3-Amino-piperidine-2,6-dione hydrochloride
    Cas Number:  25181-50-4       EC Number: 843-727-6
    Formula:  C5H9ClN2O2
    Molecular weight:  164.59
    Synonyms:  AT11186 | CS-0129473 | (3S)-3-aminopiperidine-2,6-dione hydrochloride | WS-01490 | (S)-3-AMINOPIPERI...
    SMILES:  C1CC(=O)NC(=O)C1N.Cl
    InChIKey:  YCPULGHBTPQLRH-DFWYDOINSA-N
    InChI:  InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H/t3-;/m0./s1
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  1. Small molecule 22 items
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  1. C5 7 items
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  4. BRD9 3 items
  5. BRD7 3 items
  6. CYP2D6 2 items
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  1. Primary antibody 10 items
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  1. Animal Model 9 items
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  1. Binding Activity 1 item
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  8. ≥85% 1 item
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  10. ≥94%(GC) 1 item
  11. ≥97%(GC) 1 item
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  13. ≥99.9% metals basis 1 item
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  1. Protein fragment 2 items
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  1. CHO supernatant 9 items
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  1. INHIBITOR 16 items
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