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Search results for: '1342'
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1-Trimethylsulyl-1-Butyne
Cas Number: 62108-37-6Formula: C7H14SiMolecular weight: 126.27Synonyms: AKOS027469318 | But-1-Ynyl-Trimethyl-Silane; 1-Butynyltrimethyl-Silane; Silane, 1-Butynyltrimethyl- ...SMILES: CCC#C[Si](C)(C)CInChIKey: QKUFWNQHBGARJY-UHFFFAOYSA-NInChI: InChI=1S/C7H14Si/c1-5-6-7-8(2,3)4/h5H2,1-4H3
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Dodecamethylbambus[6]uril hydrate, BU[6]
Cas Number: 1227292-62-7Formula: C42H60N24O12Molecular weight: 1093.08SMILES: CN1C2C(N(C1=O)C)N3CN4C5C(N(C(=O)N5C)C)N(C4=O)CN6C7C(N(C(=O)N7C)C)N(C6=O)CN8C9C(N(C(=O)N9C)C)N(C8=O)CN1C4C(N(C(=O)N4C)C)N(C1=O)CN1C4C(N(C(=O)N4C)C)N(C1=O)CN2C3=OInChIKey: NWWBPKVPRVOAOB-JHBMUIHZSA-NInChI: See more
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M344
Cas Number: 251456-60-7Formula: C16H25N3O3Molecular weight: 307.39Synonyms: EC-000.2275 | N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide | Histone Deacetylase Inhibitor I...SMILES: CN(C)C1=CC=C(C=C1)C(=O)NCCCCCCC(=O)NOInChIKey: MXWDSZWTBOCWBK-UHFFFAOYSA-NInChI: InChI=1S/C16H25N3O3/c1-19(2)14-10-8-13(9-11-14)16(21)17-12-6-4-3-5-7-15(20)18-22/h8-11,22H,3-7,12H2,1-2H3,(H,17,21)(H,18,20)
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DDR Inhibitor
Cas Number: 1644069-80-6(DMSO)Formula: C23H20FN5O2Molecular weight: 417.44SMILES: CC1=C(C=C(C=C1)CNC(=O)NC2=CC(=CC=C2)F)NC(=O)C3=CN=C4N3C=CC=C4
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DDR Inhibitor
Cas Number: 1644069-80-6Formula: C23H20FN5O2Molecular weight: 417.44SMILES: CC1=C(C=C(C=C1)CNC(=O)NC2=CC(=CC=C2)F)NC(=O)C3=CN=C4N3C=CC=C4InChIKey: ZPVUIOVIUFJGHO-UHFFFAOYSA-NInChI: InChI=1S/C23H20FN5O2/c1-15-8-9-16(13-26-23(31)27-18-6-4-5-17(24)12-18)11-19(15)28-22(30)20-14-25-21-7-2-3-10-29(20)21/h2-12,14H,13H2,1H3,(H,28,30)(H2,26,27,31)
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N-[5-[[(3-fluorophenyl)carbamoylamino]methyl]-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide, Inhibitor of discoidin domain receptor tyrosine kinase 1
Synonyms: compound 4SMILES: O=C(Nc1cccc(c1)F)NCc1ccc(c(c1)NC(=O)c1cnc2n1cccc2)CInChIKey: ZPVUIOVIUFJGHO-UHFFFAOYSA-NInChI: InChI=1S/C23H20FN5O2/c1-15-8-9-16(13-26-23(31)27-18-6-4-5-17(24)12-18)11-19(15)28-22(30)20-14-25-21-7-2-3-10-29(20)21/h2-12,14H,13H2,1H3,(H,28,30)(H2,26,27,31)
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VU6015929
Cas Number: 2442597-56-8Formula: C24H19F4N5O2Molecular weight: 485.43Synonyms: 4-Fluoro-3-(((5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)methyl)amino)-N-(3- (trifluoromethoxy)phenyl)...SMILES: CN1C=CC(=N1)C2=CN=CC(=C2)CNC3=C(C=CC(=C3)C(=O)NC4=CC(=CC=C4)OC(F)(F)F)FInChIKey: IZKVIUJIUTXIRH-UHFFFAOYSA-NInChI: InChI=1S/C24H19F4N5O2/c1-33-8-7-21(32-33)17-9-15(12-29-14-17)13-30-22-10-16(5-6-20(22)25)23(34)31-18-3-2-4-19(11-18)35-24(26,27)28/h2-12,14,30H,13H2,1H3,(H,31,34)
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CP-547632, Vascular endothelial growth factor receptor 2 inhibitor
Cas Number: 252003-65-9Formula: C20H24BrF2N5O3SMolecular weight: 532.42Synonyms: J-515608 | 3-(4-bromo-2,6-difluorobenzyloxy)-5-[3-[4-(1-pyrrolidinyl)butyl]ureido]isothiazole-4-carb...SMILES: C1CCN(C1)CCCCNC(=O)NC2=C(C(=NS2)OCC3=C(C=C(C=C3F)Br)F)C(=O)NInChIKey: HXHAJRMTJXHJJZ-UHFFFAOYSA-NInChI: InChI=1S/C20H24BrF2N5O3S/c21-12-9-14(22)13(15(23)10-12)11-31-18-16(17(24)29)19(32-27-18)26-20(30)25-5-1-2-6-28-7-3-4-8-28/h9-10H,1-8,11H2,(H2,24,29)(H2,25,26,30)
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7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[3-(trifluoromethyl)phenyl]-1,2-benzoxazol-3-amine, Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2
Synonyms: compound 1SMILES: Cc1ccc2c(c1C#Cc1cnc3n1nccc3)onc2Nc1cccc(c1)C(F)(F)FInChIKey: GDBAAUWGHRTFSE-UHFFFAOYSA-NInChI: InChI=1S/C23H14F3N5O/c1-14-7-9-19-21(18(14)10-8-17-13-27-20-6-3-11-28-31(17)20)32-30-22(19)29-16-5-2-4-15(12-16)23(24,25)26/h2-7,9,11-13H,1H3,(H,29,30)
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RIPK3 inhibitor 18, Inhibitor of discoidin domain receptor tyrosine kinase 2;Inhibitor of EPH receptor A5;Inhibitor of EPH receptor A8;Inhibitor of EPH receptor B2;Inhibitor of FGR proto-oncogene; Src family tyrosine kinase;Inhibitor of MET proto-oncogene; receptor tyrosine
SMILES: O=C(C1CC1)Nc1nccc(c1)Oc1ccc(c(c1C)C)NC(=O)c1cccn(c1=O)c1ccc(cc1)FInChIKey: PETCZXAONWLUFT-UHFFFAOYSA-NInChI: InChI=1S/C29H25FN4O4/c1-17-18(2)25(38-22-13-14-31-26(16-22)33-27(35)19-5-6-19)12-11-24(17)32-28(36)23-4-3-15-34(29(23)37)21-9-7-20(30)8-10-21/h3-4,7-16,19H,5-6H2,1-2H3,(H,32,36)(H,31,33,35)
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DDR1 Inhibitor 7rh
Cas Number: 1429617-90-2Formula: C30H29F3N6OMolecular weight: 546.59Synonyms: 4-Ethyl-N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)-phenyl)-3-(pyrazolo[1,5-a]pyrimi...SMILES: CCC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)CN3CCN(CC3)C)C#CC4=CN5C(=CC=N5)N=C4InChIKey: DDLPXZXBWGJRGK-UHFFFAOYSA-NInChI: InChI=1S/C30H29F3N6O/c1-3-23-6-7-25(16-24(23)5-4-21-18-34-28-8-9-35-39(28)20-21)29(40)36-27-15-22(14-26(17-27)30(31,32)33)19-38-12-10-37(2)11-13-38/h6-9,14-18,20H,3,10-13,19H2,1-2H3,(H,36,40)
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DDR1-IN-1, Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2
Cas Number: 1449685-96-4Formula: C30H31F3N4O3Molecular weight: 552.59Synonyms: AOZPVMOOEJAZGK-UHFFFAOYSA-N | BDBM104009 | 4-((4-Ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-(2-oxoind...SMILES: CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)FInChIKey: AOZPVMOOEJAZGK-UHFFFAOYSA-NInChI: See more
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Naporafenib (LXH254), B-raf/RAF proto-oncogene serine/threonine-protein kinase inhibitor
Cas Number: 1800398-38-2Formula: C25H25F3N4O4Molecular weight: 502.49Synonyms: LXH254|Naporafenib|1800398-38-2|LXH-254|N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methyl...SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=NC=C2)C(F)(F)F)C3=CC(=NC(=C3)OCCO)N4CCOCC4InChIKey: UEPXBTCUIIGYCY-UHFFFAOYSA-NInChI: InChI=1S/C25H25F3N4O4/c1-16-2-3-19(30-24(34)17-4-5-29-21(12-17)25(26,27)28)15-20(16)18-13-22(32-6-9-35-10-7-32)31-23(14-18)36-11-8-33/h2-5,12-15,33H,6-11H2,1H3,(H,30,34)
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Sitravatinib (MGCD516)
Cas Number: 1123837-84-2(DMSO)Formula: C33H29F2N5O4SMolecular weight: 629.68Synonyms: MG-516 | 1,1-Cyclopropanedicarboxamide, N-[3-fluoro-4-[[2-[5-[[(2-meth...SMILES: COCCNCC1=CC=C(N=C1)C2=CC3=C(S2)C(=CC=N3)OC4=CC=C(NC(=O)C5(CC5)C(=O)NC6=CC=C(F)C=C6)C=C4F
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DDR1/2 inhibitor 5n, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2;Inhibitor of EPH receptor A2;Inhibitor of EPH receptor A7;Inhibitor of EPH re
Cas Number: 2241813-33-0Formula: C31H31F3N6OMolecular weight: 560.60SMILES: CN1CCN(CC1)Cc1cc(NC(=O)c2ccc(c(c2)C#Cc2cnc3n2ccnc3)C(C)C)cc(c1)C(F)(F)FInChIKey: IUGBGEUCXVKGQK-UHFFFAOYSA-NInChI: InChI=1S/C31H31F3N6O/c1-21(2)28-7-5-24(16-23(28)4-6-27-18-36-29-19-35-8-9-40(27)29)30(41)37-26-15-22(14-25(17-26)31(32,33)34)20-39-12-10-38(3)11-13-39/h5,7-9,14-19,21H,10-13,20H2,1-3H3,(H,37,41)
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Tozasertib, Serine/threonine-protein kinase Aurora inhibitor
Cas Number: 639089-54-6Formula: C23H28N8OSMolecular weight: 464.6Synonyms: VX-680 | MK-0457 | Cyclopropane carboxylic acid{4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2H-pyrazo...SMILES: CC1=CC(=NN1)NC2=CC(=NC(=N2)SC3=CC=C(C=C3)NC(=O)C4CC4)N5CCN(CC5)CInChIKey: GCIKSSRWRFVXBI-UHFFFAOYSA-NInChI: InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)
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MnTMPyP pentachloride
Cas Number: 100012-18-8Formula: C44H36MnN8Cl5Molecular weight: 909Synonyms: 4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide | S...SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)FInChIKey: MLDQJTXFUGDVEO-UHFFFAOYSA-NInChI: InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
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FGFR1/DDR2 inhibitor 1
Cas Number: 2308497-58-5(DMSO)Formula: C28H22F3N5OMolecular weight: 501.5SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=C(C=C3)C(=NN4)C5=CN(N=C5)C6CC6
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PD173955, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase
Cas Number: 260415-63-2Formula: C21H16Cl2N4OSMolecular weight: 443.35Synonyms: 260415-63-2|PD173955|PD-173955|6-(2,6-dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido...SMILES: CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC(=CC=C4)SCInChIKey: VAARYSWULJUGST-UHFFFAOYSA-NInChI: InChI=1S/C21H16Cl2N4OS/c1-27-19-12(9-15(20(27)28)18-16(22)7-4-8-17(18)23)11-24-21(26-19)25-13-5-3-6-14(10-13)29-2/h3-11H,1-2H3,(H,24,25,26)
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Masitinib (AB1010), Platelet-derived growth factor receptor inhibitor
Cas Number: 790299-79-5(DMSO)Formula: C28H30N6OSMolecular weight: 498.64Synonyms: N-(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamideSMILES: CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC(=C(C)C=C3)NC4=NC(=CS4)C5=CC=CN=C5
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AST-487 (NVP-AST487), Tyrosine-protein kinase receptor RET inhibitor
Cas Number: 630124-46-8Formula: C26H30F3N7O2Molecular weight: 529.56Synonyms: 630124-46-8|AST 487|AST-487|NVP-AST487|1-(4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)pheny...SMILES: CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)FInChIKey: ODPGGGTTYSGTGO-UHFFFAOYSA-NInChI: InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)
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