sp_pcsk9-Aladdin Scientific

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Anacetrapib, Cholesteryl ester transfer protein inhibitor

Grade & Purity:

≥98%

Cas Number: 875446-37-0

Formula: C₃₀H₂₅F₁₀NO₃ Molecular Weight: 637.51

IUPAC Name: (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-show more

SMILES: CC1C(OC(=O)N1CC2=C(C=CC(=C2)C(F)(F)F)C3=CC(=C(C=C3OC)F)C(C)C)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F

InChIKey: MZZLGJHLQGUVPN-HAWMADMCSA-N

InChI: InChI=1S/C30H25F10NO3/c1-14(2)22-11-23(25(43-4)12-24(22)31)21-6-5-18(28(32,33)34)9-17(21)13-41-15(3)26(44-27(41)42)16-7-19(29(35,36)37)10-20(8-16)30(3show more

Synonyms: Anacetrapib - MK-0859 | s2748 | KBio3_001100 | MLS006010190 | A24886 | BDBM50348228 | STL554443 | Anacetrapib (JAN/US...

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Pep 2-8

Grade & Purity:

≥95%

Cas Number: 1541011-97-5 Compound CID: 124221781

Formula: C₈₃H₁₁₀N₁₆O₂₄ Molecular Weight: 1715.88

IUPAC Name: (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoshow more

SMILES: CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C(C)C)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC4=CNC5=CC=show more

InChIKey: ORPZALWAWWEEDP-NXXUBLNKSA-N

InChI: InChI=1S/C83H110N16O24/c1-40(2)31-57(74(114)94-62(36-66(109)110)77(117)92-61(79(119)97-67(41(3)4)71(84)111)35-49-38-86-54-22-16-14-20-52(49)54)90-75(1show more

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2-Hydroxy-5-methoxy-3-undecyl-[1,4]benzoquinone

Cas Number: 56005-10-8

Formula: C₁₈H₂₈O₄ Molecular Weight: 308.418

IUPAC Name: 2-hydroxy-5-methoxy-3-undecylcyclohexa-2,5-diene-1,4-dione

SMILES: CCCCCCCCCCCC1=C(C(=O)C=C(C1=O)OC)O

InChIKey: KHBJLRRAMCJZLZ-UHFFFAOYSA-N

InChI: InChI=1S/C18H28O4/c1-3-4-5-6-7-8-9-10-11-12-14-17(20)15(19)13-16(22-2)18(14)21/h13,20H,3-12H2,1-2H3

Synonyms: HY-W510159 | 4H3R9623BA | 2,5-Cyclohexadiene-1,4-dione, 2-hydroxy-5-methoxy-3-undecyl- | 2-hydroxy-5-methoxy-3-undecy...

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Alirocumab (anti-PCSK9)

Grade & Purity:

Moligand™

≥95%
75mg/ml in buffer

Associated targets: PCSK9

Isotype: Human IgG1

Cas Number: 1245916-14-6

SMILES: C(C(COP(=O)(O)O)O)O.[Na].[Na]

InChIKey: CATWCRUATKKAAQ-UHFFFAOYSA-N

InChI: InChI=1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;

Synonyms: BCP25199 | CID 88214187 | 1245916-14-6 | B0084-007210 | SCHEMBL7870957 | BA165582

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PF-06446846

Grade & Purity:

≥98%

Cas Number: 1632250-49-7 Compound CID: 86271238

Formula: C₂₂H₂₀ClN₇O Molecular Weight: 433.89

IUPAC Name: N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(triazolo[4,5-b]pyridin-3-yl)benzamide

SMILES: C1CC(CNC1)N(C2=C(C=CC=N2)Cl)C(=O)C3=CC=C(C=C3)N4C5=C(C=CC=N5)N=N4

InChIKey: FDTXHWQFIXYHCL-QGZVFWFLSA-N

InChI: InChI=1S/C22H20ClN7O/c23-18-5-2-12-25-20(18)29(17-4-1-11-24-14-17)22(31)15-7-9-16(10-8-15)30-21-19(27-28-30)6-3-13-26-21/h2-3,5-10,12-13,17,24H,1,4,11show more

Synonyms: N-(3-Chloropyridin-2-yl)-N-((3R)-piperidin-3-yl)-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide

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R-IMPP

Grade & Purity:

10mM in DMSO

Cas Number: 2133832-83-2 Compound CID: 122198706

Formula: C₂₄H₂₇N₃O₂ Molecular Weight: 389.49

IUPAC Name: N-isoquinolin-1-yl-3-(4-methoxyphenyl)-N-[(3R)-piperidin-3-yl]propanamide

SMILES: COC1=CC=C(C=C1)CCC(=O)N(C2CCCNC2)C3=NC=CC4=CC=CC=C43

InChIKey: OKTGXQMSOIQCTJ-HXUWFJFHSA-N

InChI: InChI=1S/C24H27N3O2/c1-29-21-11-8-18(9-12-21)10-13-23(28)27(20-6-4-15-25-17-20)24-22-7-3-2-5-19(22)14-16-26-24/h2-3,5,7-9,11-12,14,16,20,25H,4,6,10,13show more

Synonyms: (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide | PF-00932239

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R-IMPP

Grade & Purity:

≥98%

Cas Number: 2133832-83-2 Compound CID: 122198706

Formula: C₂₄H₂₇N₃O₂ Molecular Weight: 389.49

IUPAC Name: N-isoquinolin-1-yl-3-(4-methoxyphenyl)-N-[(3R)-piperidin-3-yl]propanamide

SMILES: COC1=CC=C(C=C1)CCC(=O)N(C2CCCNC2)C3=NC=CC4=CC=CC=C43

InChIKey: OKTGXQMSOIQCTJ-HXUWFJFHSA-N

InChI: InChI=1S/C24H27N3O2/c1-29-21-11-8-18(9-12-21)10-13-23(28)27(20-6-4-15-25-17-20)24-22-7-3-2-5-19(22)14-16-26-24/h2-3,5,7-9,11-12,14,16,20,25H,4,6,10,13show more

Synonyms: (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide | PF-00932239

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SBC-110736

Grade & Purity:

10mM in DMSO

Cas Number: 1629166-02-4 Compound CID: 78425817

Formula: C₂₆H₂₇N₃O₂ Molecular Weight: 413.51

IUPAC Name: N-[4-[4-(4-methylphenyl)-2-phenylpiperazine-1-carbonyl]phenyl]acetamide

SMILES: CC1=CC=C(C=C1)N2CCN(C(C2)C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)NC(=O)C

InChIKey: PILMFSWQYWYOJC-UHFFFAOYSA-N

InChI: InChI=1S/C26H27N3O2/c1-19-8-14-24(15-9-19)28-16-17-29(25(18-28)21-6-4-3-5-7-21)26(31)22-10-12-23(13-11-22)27-20(2)30/h3-15,25H,16-18H2,1-2H3,(H,27,30)

Synonyms: N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide

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SBC-110736

Grade & Purity:

≥98%

Cas Number: 1629166-02-4 Compound CID: 78425817

Formula: C₂₆H₂₇N₃O₂ Molecular Weight: 413.51

IUPAC Name: N-[4-[4-(4-methylphenyl)-2-phenylpiperazine-1-carbonyl]phenyl]acetamide

SMILES: CC1=CC=C(C=C1)N2CCN(C(C2)C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)NC(=O)C

InChIKey: PILMFSWQYWYOJC-UHFFFAOYSA-N

InChI: InChI=1S/C26H27N3O2/c1-19-8-14-24(15-9-19)28-16-17-29(25(18-28)21-6-4-3-5-7-21)26(31)22-10-12-23(13-11-22)27-20(2)30/h3-15,25H,16-18H2,1-2H3,(H,27,30)

Synonyms: N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide

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SBC-115076

Grade & Purity:

10mM in DMSO

Cas Number: 489415-96-5 Compound CID: 5734410

Formula: C₃₁H₃₃N₃O₅ Molecular Weight: 527.61

IUPAC Name: (4E)-4-[hydroxy-(3-methyl-4-phenylmethoxyphenyl)methylidene]-1-(3-morpholin-4-ylpropyl)-5-pyridin-4-ylpyrrolidine-2,3-dione

SMILES: CC1=C(C=CC(=C1)C(=C2C(N(C(=O)C2=O)CCCN3CCOCC3)C4=CC=NC=C4)O)OCC5=CC=CC=C5

InChIKey: VVYIXKBHQQSREP-ORIPQNMZSA-N

InChI: InChI=1S/C31H33N3O5/c1-22-20-25(8-9-26(22)39-21-23-6-3-2-4-7-23)29(35)27-28(24-10-12-32-13-11-24)34(31(37)30(27)36)15-5-14-33-16-18-38-19-17-33/h2-4,6show more

Synonyms: 4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one

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SBC-115076

Grade & Purity:

≥98%

Cas Number: 489415-96-5 Compound CID: 5734410

Formula: C₃₁H₃₃N₃O₅ Molecular Weight: 527.61

IUPAC Name: (4E)-4-[hydroxy-(3-methyl-4-phenylmethoxyphenyl)methylidene]-1-(3-morpholin-4-ylpropyl)-5-pyridin-4-ylpyrrolidine-2,3-dione

SMILES: CC1=C(C=CC(=C1)C(=C2C(N(C(=O)C2=O)CCCN3CCOCC3)C4=CC=NC=C4)O)OCC5=CC=CC=C5

InChIKey: VVYIXKBHQQSREP-ORIPQNMZSA-N

InChI: InChI=1S/C31H33N3O5/c1-22-20-25(8-9-26(22)39-21-23-6-3-2-4-7-23)29(35)27-28(24-10-12-32-13-11-24)34(31(37)30(27)36)15-5-14-33-16-18-38-19-17-33/h2-4,6show more

Synonyms: 4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one

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Alirocumab (anti-PCSK9), Antibody of proprotein convertase subtilisin/kexin type 9

Grade & Purity:

≥95%(SDS-PAGE&SEC-HPLC)
See COA

Application:

Animal Model
ELISA
Flow Cytometry
Functional Assay

Associated targets: PCSK9

Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Species reactivity（Reacts with): Cynomolgus monkey, Human, Mouse Isotype: Human IgG1

Host species: Human Conjugation: Unconjugated

Cas Number: 1245916-14-6

SMILES: C(C(COP(=O)(O)O)O)O.[Na].[Na]

InChIKey: CATWCRUATKKAAQ-UHFFFAOYSA-N

InChI: InChI=1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;

Synonyms: Recombinant Alirocumab Antibody | REGN 727 | SAR 236553 | Alirocumab (anti-PCSK9) | Anti-PCSK9 Reference Antibody (al...

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