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Microtubule/Tubulin

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Items 13-24 of 239

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  1. , Tubulin inhibitor
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    Indibulin, Tubulin inhibitor
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 204205-90-3
    Formula:  C22H16ClN3O2        Molecular Weight: 389.83
    IUPAC Name:  2-[1-[(4-chlorophenyl)methyl]indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide
    SMILES:  C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C(=O)C(=O)NC4=CC=NC=C4
    InChIKey: SOLIIYNRSAWTSQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H16ClN3O2/c23-16-7-5-15(6-8-16)13-26-14-19(18-3-1-2-4-20(18)26)21(27)22(28)25-17-9-11-24-12-10-17/h1-12,14H,13H2,(H,24,25,28)
    Synonyms: D 24851 | 2-[1-(4-Chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide | ZIO 301
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    Bicyclol
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 118159-48-1
    Formula:  C19H18O9        Molecular Weight: 390.34
    IUPAC Name:  methyl 4-[5-(hydroxymethyl)-7-methoxy-1,3-benzodioxol-4-yl]-7-methoxy-1,3-benzodioxole-5-carboxylate
    SMILES:  COC1=C2C(=C(C(=C1)CO)C3=C4C(=C(C=C3C(=O)OC)OC)OCO4)OCO2
    InChIKey: KXMTXZACPVCDMH-UHFFFAOYSA-N
    InChI:  InChI=1S/C19H18O9/c1-22-11-4-9(6-20)13(17-15(11)25-7-27-17)14-10(19(21)24-3)5-12(23-2)16-18(14)28-8-26-16/h4-5,20H,6-8H2,1-3H3
    Synonyms: 4,4'-Bi-1,3-benzodioxole)-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester | 5'-(hydroxymethyl)-7,...
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    Mertansine (DM1 Compound)
      Grade & Purity: 
    • ≥98%
    Cas Number: 139504-50-0
    Formula:  C35H48ClN3O10S        Molecular Weight: 738.29
    IUPAC Name:  [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0show more
    SMILES:  CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCS)C)C)OC)(NC(=O)O2)O
    InChIKey: ANZJBCHSOXCCRQ-FKUXLPTCSA-N
    InChI:  InChI=1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-2show more
    Synonyms: N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine, L- | CHEBI:82755 | DDZ29HGH0E | Q4515649 | Mertansine (DM1) | m...
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    KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole)
      Grade & Purity: 
    • ≥98%
    Cas Number: 129414-88-6
    Formula:  C19H19NO4        Molecular Weight: 325.36
    IUPAC Name:  4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-1,2-oxazol-5-yl]phenol
    SMILES:  CCC1=CC(=C(C=C1OC)O)C2=C(C=NO2)C3=CC=C(C=C3)OC
    InChIKey: BNBHIGLOMVMJDB-UHFFFAOYSA-N
    InChI:  InChI=1S/C19H19NO4/c1-4-12-9-15(17(21)10-18(12)23-3)19-16(11-20-24-19)13-5-7-14(22-2)8-6-13/h5-11,21H,4H2,1-3H3
    Synonyms: 4-Ethyl-3-methoxy-6-[4-(4-methoxyphenyl)-1,2-oxazol-5(2H)-ylidene]cyclohexa-2,4-dien-1-one | 5-(5-Ethyl-2-hydroxy-4-m...
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    Paclitaxel-d5
      Grade & Purity: 
    • ≥98 atom% D,≥95%
    Cas Number: 1129540-33-5
    Formula:  C47H46D5NO14        Molecular Weight: 858.94
    IUPAC Name:  [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2,3,4,5,6-pentadeuteriobenzoyl)amino]-3-phenylpropanoyl]oxy-show more
    SMILES:  CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
    InChIKey: RCINICONZNJXQF-JQTCHTAZSA-N
    InChI:  InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51show more
    Synonyms: Abraxane-d5 | Genaxol-d5 | Genetaxyl-d5 | OncoGel-d5 | Onxal-d5 | Pacliex-d5 | (-)-Paclitaxel-d5 | Taxol-d5 | Yewtaxa...
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    Vc-MMAD
      Grade & Purity: 
    • ≥97%
    Cas Number: 1401963-17-4        Compound CID:  78357803
    Formula:  C70H104N12O14S        Molecular Weight: 1369.71
    IUPAC Name:  [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-show more
    SMILES:  CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC4=CC=C(C=C4)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(show more
    InChIKey: GRBICHHPFYWKKI-BDVWXETGSA-N
    InChI:  InChI=1S/C70H104N12O14S/c1-14-45(8)61(53(94-12)40-57(86)81-37-22-26-52(81)62(95-13)46(9)63(87)76-51(67-72-35-38-97-67)39-47-23-17-15-18-24-47)79(10)68show more
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    VcMMAE
      Grade & Purity: 
    • ≥98%
    Cas Number: 646502-53-6        Compound CID:  46944733
    Formula:  C68H105N11O15        Molecular Weight: 1316.63
    IUPAC Name:  [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-show more
    SMILES:  CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(C)C)Nshow more
    InChIKey: NLMBVBUNULOTNS-HOKPPMCLSA-N
    InChI:  InChI=1S/C68H105N11O15/c1-15-43(8)59(51(92-13)38-55(83)78-37-23-27-50(78)61(93-14)44(9)62(85)71-45(10)60(84)47-24-18-16-19-25-47)76(11)66(89)57(41(4)5show more
    Synonyms: A14362 | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E | s6661 | VEDOTIN PARENT ...
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    Vincristine sulfate
      Grade & Purity: 
    • ≥98%
    Cas Number: 2068-78-2        EC Number: 218-190-0        Compound CID:  249332
    Formula:  C46H56N4O10·H2SO4        Molecular Weight: 923.04
    IUPAC Name:  methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nshow more
    SMILES:  CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
    InChIKey: AQTQHPDCURKLKT-JKDPCDLQSA-N
    InChI:  InChI=1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)3show more
    Synonyms: SCHEMBL3710 | VINCRISTINE SULFATE (MART.) | VINCRISTINE SULFATE (USP-RS) | Vincristine sulphate | 22-OXOVINCALEUKOBLA...
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    Vindoline
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 2182-14-1        EC Number: 218-558-0        Compound CID:  260535
    Formula:  C25H32N2O6        Molecular Weight: 456.53
    IUPAC Name:  methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tshow more
    SMILES:  CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C
    InChIKey: CXBGOBGJHGGWIE-ACSXSLCXSA-N
    InChI:  InChI=1S/C25H32N2O6/c1-6-23-10-7-12-27-13-11-24(19(23)27)17-9-8-16(31-4)14-18(17)26(3)20(24)25(30,22(29)32-5)21(23)33-15(2)28/h7-10,14,19-21,30H,6,11-show more
    Synonyms: CHEBI:16380 | NSC-628056 | MFCD27991347 | methyl 4beta-acetyloxy-3beta-hydroxy-16-methoxy-1-methyl-6,7-didehydro-2bet...
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    Vinorelbine ditartrate salt hydrate
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 125317-39-7
    Formula:  C45H54N4O8·2C4H6O6·xH2O        Molecular Weight: 1079.11（dry basis）
    IUPAC Name:  (2R,3R)-2,3-dihydroxybutanedioic acid;methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(12S,14S)-16-ethyl-12-methoxycarbonyl-1,10-diazatetracycshow more
    SMILES:  CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O.C(C(C(=O)O)show more
    InChIKey: CILBMBUYJCWATM-LNLXBTRNSA-N
    InChI:  InChI=1S/C45H54N4O8.2C4H6O6/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)show more
    Synonyms: KW-2307 | Vinorelbine Bitartrate | 1217449-57-4 | Q-100110 | (2R,3R)-2,3-dihydroxybutanedioic acid;methyl (1R,9R,10S,...
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    Ombrabulin hydrochloride
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 253426-24-3        Compound CID:  6918404
    Formula:  C21H27ClN2O6        Molecular Weight: 438.9
    IUPAC Name:  (2S)-2-amino-3-hydroxy-N-[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide;hydrochloride
    SMILES:  COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)NC(=O)C(CO)N.Cl
    InChIKey: UQNRTPFLTRZEIM-MRWUDIQNSA-N
    InChI:  InChI=1S/C21H26N2O6.ClH/c1-26-17-8-7-13(9-16(17)23-21(25)15(22)12-24)5-6-14-10-18(27-2)20(29-4)19(11-14)28-3;/h5-11,15,24H,12,22H2,1-4H3,(H,23,25);1H/show more
    Synonyms: Ombrabulin hydrochloride (JAN) | SCHEMBL1419930 | CPMO | AC7700 (hydrochloride) | AVE8062 (hydrochloride) | (z)-N-[2-...
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    Methylene blue
      Grade & Purity: 
    • ≥70%
    Cas Number: 61-73-4
    Formula:  C16H18ClN3S        Molecular Weight: 319.85
    IUPAC Name:  [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride
    SMILES:  CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
    InChIKey: CXKWCBBOMKCUKX-UHFFFAOYSA-M
    InChI:  InChI=1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
    Synonyms: Methylene Blue BB (Zinc Free) | Methylene Blue USP (Medicinal) | 3H-Phenothiazine, 7-(dimethylamino)-3-(methylimino)-...
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  1. Small molecule 150 items
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  1. Recombinant 4 items
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