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Antibody Therapeutics

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  1. Recombinant Mouse CD40/TNFRSF5 Protein
      Species: Mouse    Accession #: P27512    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD40/TNFRSF5 is immobilized at 1 µg/mL (100 µL/well), the concentration of Recombinant Mouse CD40 Ligand/TNFSF5 that produces 50% optimal binding is found to be 100-600 ng/mL.    
    Synonyms: Tnfrsf5 | B-cell surface antigen CD40 | B cell surface antigen CD40 | Bp50B cell-associated molecule | CD40 antigen |...
  2. Recombinant Human NKp30/NCR3 Protein
      Species: Human    Accession #: O14931-1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. When Recombinant Human B7-H6 Fc Chimera is immobilized at 4 µg/mL (100 µL/well), Recombinant Human NKp30/NCR3 His-tag binds with an ED50 of 0.600-7.20 µg/mL.    
    Synonyms: Activating natural killer receptor p30 | Natural killer cell p30-related protein | NKp30 | NK-p30 | CD337 antigen | A...
  3. Recombinant Human LAIR1 Protein
      Species: Human    Accession #: Q6GTX8    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by the ability of the immobilized protein to support the adhesion of HeLa human cervical epithelial carcinoma cells. The ED50 for this effect is 0.25-1.0 μg/mL.    
    Synonyms: CD305 | CD305 antigen | CD305leukocyte-associated Ig-like receptor 1 | HLAIR1 | LAIR1 | LAIR-1 | leukocyte-associated...
  4. Recombinant Human Nectin-2/CD112 Protein
      Species: Human    Accession #: Q92692-2    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. When Recombinant Human Nectin‑2/CD112 Fc Chimera is immobilized at 0.5 µg/mL (100 µL/well), the concentration of Recombinant Human DNAM‑1 Fc Chimera that produces 50% of the optimal binding response is 0.04-0.2 μg/mL.    
    Synonyms: Herpes virus entry mediator B | Herpesvirus entry mediator B | HveB | Nectin cell adhesion molecule 2 | Poliovirus re...
  5. Recombinant Human CD160 Protein
      Species: Human    Accession #: O95971    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: When recombinant mouse HVEM Fc Chimera is immobilized at 0.5 μg/mL, 100 μL/well, the concentration of recombinant human CD160 that produces 50% of the optimal binding response is found to be approximately 0.1 ‑ 0.6 μg/mL.    
    Synonyms: BY55_HUMAN | BY55 | CD160 | CD160 antigen | CD160 antigen [Precursor] | CD160 delta Ig | CD160 molecule | CD160 trans...
  6. Recombinant Human LILRA1/CD85i/LIR-6 Protein
      Species: Human    Accession #: O75019-1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. When Recombinant Human LILRA1/CD85i/LIR-6 is coated at 2 µg/mL, Recombinant Human Angiopoietin-like 7/ANGPTL7 binds with an ED50 = 0.3-1.8 µg/mL.    
    Synonyms: CD85i antigen | CD85 antigen-like family member I | CD85i | leukocyte immunoglobulin-like receptor subfamily A member...
  7. Recombinant Human Chitotriosidase/CHIT1 Protein
      Species: Human    Accession #: Q13231    
      Expression system: HEK293    Protein Tag: C-10His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to cleave 4-Methylumbelliferyl-beta -D-N,N’,N”-triacetylchitotriose (4-MU-TACT). The specific activity is >1,500 pmol/min/µg, as measured under the described conditions.    
    Synonyms: Chitinase-1 | EC 3.2.1.14 | CHIT1 | CHI3 | CHITCHI3 | chitinase 1 (chitotriosidase) | chitinase-1 | Chitotriosidase |...
  8. Recombinant Human LILRA2/CD85h/ILT1 Protein
      Species: Human    Accession #: Q8N149-1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. When Recombinant Human LILRA2/CD85h/ILT1 is coated at 2 µg/mL, Recombinant Human Angiopoietin-like Protein 7/ANGPTL7 binds with a typical ED50 of 0.2 -1.2 μg/mL.    
    Synonyms: CD85 antigen-like family member H | CD85h antigen | CD85h | ILT1 | ILT-1 | Leukocyte immunoglobulin-like receptor 7 |...
  9. Recombinant Human Nectin-3 Protein
      Species: Human    Accession #: Q9NQS3-1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. Immobilized rhNectin-3/his at 1 µg/mL can bind rhNectin-1/his with an apparent KD <120 nM.    
    Synonyms: CDw113 | Nectin cell adhesion molecule 3 | Poliovirus receptor-related protein 3 | Poliovirus Receptor Related 3 | CD...
  10. Recombinant Human CD40/TNFRSF5 Protein
      Species: Human    Accession #: P25942    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Immobilized Recombinant Human CD40 Protein (rp183577) at 1.0 μg/mL can bind Recombinant Human CD40 Ligand Protein (rp169583) with the EC50 of 20.84 ng/mL.     Immobilized Recombinant Human CD40 Protein (rp183577) at 1.0 μg/mL can bind CD40 Mouse mAb (Ab094764) with the EC50 of 15.35 ng/mL. Immobilized Recombinant Human CD40 Protein (rp183577) at 1.0 μg/mL can bind Ravagalimab (anti-CD40) (Ab182860) with the EC50 of 11.32 ng/mL. Immobilized Recombinant Human CD40 Protein (rp183577) at 1.0 μg/mL can bind Mitazalimab (anti-CD40) (Ab182809) with the EC50 of 4.37 ng/mL. Immobilized Recombinant Human CD40 Protein (rp183577) at 1.0 μg/mL can bind Giloralimab (anti-CD40) (Ab182875) with the EC50 of 25.5 ng/mL.    
    Synonyms: B cell surface antigen CD40 | B-cell surface antigen CD40 | Bp50B cell-associated molecule | CD40 antigen | CD40 mole...
  11. Recombinant Mouse CD47 Protein
      Species: Mouse    Accession #: NP_034711    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. When Recombinant Mouse SIRP alpha /CD172a Fc Chimera is coated at 2 μg/mL, Recombinant Mouse CD47 binds with an apparent Kd <0.6 nM. Also measured by its ability to antagonize mouse red blood cell adhesion to immobilized Recombinant Mouse SIRP alpha /CD172a Fc Chimera. The ED50 for this effect is 2.0-8.0 μg/mL. Optimal dilutions should be determined by each laboratory for each application.    
    Synonyms: antigen identified by monoclonal 1D8 | Antigenic surface determinant protein OA3 | CD47 antigen (Rh-related antigen, ...
  12. Recombinant Mouse GITR/TNFRSF18 Protein
      Species: Mouse    Accession #: Q8C4K3    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its binding ability in a functional ELISA. Immobilized rmGITR/Fc Chimera at 2 µg/mL (100 µL/well) can bind rmGITR Ligand with a linear range of 0.8-50 ng/mL.    
    Synonyms: Glucocorticoid Induced TNF Receptor Family Related Gene | Activation-inducible TNFR family receptor | AITR | TNF rece...
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