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Otilimab (anti-GM-CSF) - Primary antibody, specific to CSF2, >95%, high purity, Human IgG1, INHIBITOR of Granulocyte-macrophage colony-stimulating factor inhibitor, INHIBITOR of Granulocyte-macrophage colony-stimulating factor inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175622
Grouped product items
SKU Size
Availability
Price Qty
Ab175622-100μg
100μg
10
$109.90
Ab175622-1mg
1mg
4
$519.90
Ab175622-5mg
5mg
1
$1,399.90
Ab175622-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Otilimab (anti-GM-CSF) - Primary antibody, specific to CSF2, >95%, high purity, Human IgG1, INHIBITOR of Granulocyte-macrophage colony-stimulating factor inhibitor
Synonyms Colony stimulating factor 2 (granulocyte-macrophage) antibody | Colony Stimulating Factor 2 antibody | Colony stimulating factor antibody | Colony-stimulating factor antibody | CSF 2 antibody | CSF antibody | CSF2 antibody | CSF2_HUMAN antibody | GM-CSF a
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CSF2
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Granulocyte-macrophage colony-stimulating factor inhibitor
Product Description

Otilimab (anti-GM-CSF) is an anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) humanized monoclonal antibody. Otilimab (anti-GM-CSF) neutralises the biological

Function

of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor.

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 142.22 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1638332-55-4

Associated Targets(Human)

CSF2 Tbio Granulocyte-macrophage colony-stimulating factor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Otilimab (anti-GM-CSF) (Ab175622) - ELISA
Immobilized Recombinant Human GM-CSF Protein (rp146523) at 0.5 μg/mL can bind Otilimab (anti-GM-CSF) (Ab175622) with the EC₅₀ of 55.94 ng/mL.

Otilimab (anti-GM-CSF) (Ab175622) - SEC
The purity of Otilimab (anti-GM-CSF) (Ab175622) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303094 Certificate of Analysis Mar 08, 2024 Ab175622
ZJ24F0303095 Certificate of Analysis Mar 08, 2024 Ab175622
ZJ24F0303096 Certificate of Analysis Mar 08, 2024 Ab175622

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