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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182846-100μg
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100μg |
10
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$89.90
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Ab182846-1mg
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1mg |
4
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$419.90
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Ab182846-5mg
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5mg |
1
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$1,259.90
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Ab182846-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$2,019.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Olinvacimab (anti-VEGFR2) - Primary antibody, specific to KDR, Human IgG1, INHIBITOR of Vascular endothelial growth factor receptor 2 inhibitor |
|---|---|
| Synonyms | CD309 antibody | CD309 antigen antibody | EC 2.7.10.1 antibody | Fetal liver kinase 1 antibody | FLK-1 antibody | FLK1 antibody | FLK1, mouse, homolog of antibody | Kdr antibody | Kinase insert domain receptor (a type III receptor tyrosine kinase) antibod |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | KDR |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Vascular endothelial growth factor receptor 2 inhibitor |
| Product Description |
Olinvacimab (anti-VEGFR2) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab (anti-VEGFR2) inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab (anti-VEGFR2) has antiangiogenic activity. Olinvacimab (anti-VEGFR2) can be used for the research of recurrent glioblastoma and breast cancer. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | lambda |
| SDS-PAGE | 28.6 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 214.8 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2095504-49-5 |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Olinvacimab (anti-VEGFR2) (Ab182846) - Flow Cytometry
Flow Cytometry analysis of HUVEC cells labelling VEGFR2 (red) with Olinvacimab (anti-VEGFR2) (Ab182846). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Olinvacimab (anti-VEGFR2) (Ab182846) - SEC
The purity of Olinvacimab (anti-VEGFR2) (Ab182846) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 24, 2024 | Ab182846 | |
| Certificate of Analysis | Apr 24, 2024 | Ab182846 | |
| Certificate of Analysis | Apr 24, 2024 | Ab182846 |
Starting at $109.90
Starting at $39.90
Starting at $109.90