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Belantamab mafodotin (anti-BCMA) - Primary antibody, specific to TNFRSF17, >90% (SDS-PAGE&SEC), high purity, Human IgG1, Antibody of B cell maturation antigen, Antibody of B cell maturation antigen

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: MC-VC-PAB-MMAF
In stock
Item Number
Ab175467
Grouped product items
SKU Size
Availability
Price Qty
Ab175467-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab175467-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab175467-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$809.90
Ab175467-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,289.90

Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAF)

Basic Description

Product Name Belantamab mafodotin (anti-BCMA) - Primary antibody, specific to TNFRSF17, >90% (SDS-PAGE&SEC), high purity, Human IgG1, Antibody of B cell maturation antigen
Synonyms B cell maturation antigen antibody | B cell maturation factor antibody | B cell maturation protein antibody | B-cell maturation protein antibody | BCM antibody | BCMA antibody | CD269 antibody | CD269 antigen antibody | TNFRSF17 antibody | TNR17_HUMAN ant
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Host species Human
Specificity TNFRSF17
Conjugation MC-VC-PAB-MMAF
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action Antibody of B cell maturation antigen
Product Description

Belantamab mafodotin (anti-BCMA) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. Belantamab mafodotin has anti-myeloma activity.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145 kDa
Purification Method Protein A purified
Purity >90% (SDS-PAGE&SEC)
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS 2050232-20-5

Associated Targets(Human)

TNFRSF17 Tclin Tumor necrosis factor receptor superfamily member 17 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Belantamab mafodotin (anti-BCMA) (Ab175467) - Flow Cytometry
Flow Cytometry analysis of U266 cells labelling BCMA (red) with Belantamab mafodotin (anti-BCMA) (Ab175467) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Belantamab mafodotin (anti-BCMA) (Ab175467) - ELISA
Immobilized Recombinant Human BCMA/TNFRSF17(Fc) protein (rp169554) at 1.0 μg/mL can bind Belantamab mafodotin (anti-BCMA) (Ab175467) with the EC50 of 40.09 ng/mL.

Belantamab mafodotin (anti-BCMA) (Ab175467) - ELISA
Immobilized Recombinant huBCMA- ECD-His protein at 2.0 μg/mL can bind Belantamab mafodotin (anti-BCMA) (Ab175467) with the EC50 of 26.34 ng/mL.

Belantamab mafodotin (anti-BCMA) (Ab175467) - SEC
The purity of Belantamab mafodotin (anti-BCMA) (Ab175467) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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