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Carbonic Anhydrase from bovine erythrocytes - ≥3,000 units/mg dry weight, high purity , CAS No.9001-03-0

In stock
Item Number
C128742
Grouped product items
SKU Size
Availability
Price Qty
C128742-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$254.90
C128742-50mg
50mg
3
$869.90
C128742-250mg
250mg
1
$2,999.90

Basic Description

Product Name Carbonic Anhydrase from bovine erythrocytes - ≥3,000 units/mg dry weight, high purity , CAS No.9001-03-0
Synonyms Carbonate Dehydratase | Carbonate Hydrolyase
Grade EnzymoPure™
Product Description

Specificity:

Blood CO2 transport and excretion is largely dependent on the rapid catalysis of the CO2 reactions within the erythrocyte by CA (Tufts et al. 2003). Bovine CA reversibly hydrates alkyl pyruvates and it exhibits hydratase activity toward a wide variety of substrates (Pocker et al. 1974, and Wells et al. 1975).

Protein Accession Number: P00921

CATH Classification (v. 3.2.0):

Class: Alpha Beta

Architecture: Roll

Topology: Carbonic Anhydrase II

Molecular Weight:

29.0 kDa (Theoretical)

30 kDa (Lindskog et al. 1971)

Optimal pH: 7.0-7.5 (Demir et al. 2000, and Tasgin et al. 2009)

Isoelectric Point: 6.40 (Theoretical)

Extinction Coefficient:

50,070 cm-1M-1 (Theoretical)

E1%, 280 = 19.0 (Nyman and Lindskog 1964)

Active Site Residues:

Histidine (H63)

Asparagine (N66)

Lysine (K126)

Activators:

HPO42- (Rowlett et al. 1991)

SO32- (Rowlett et al. 1991)

Inhibitors:

Monovalent anions (Lindskog et al. 1971, and Ward and Cull 1972)

Sulfonates and sulfonamides (Pocker and Watamori 1973, and Binford et al. 1974)

Imidazole (Edsall 1968)

Applications:

CO2 determination in blood

Elimination of CO2 in reagents for acidity testing

Carboxy group transfers

Reduction reactions

Specifications & Purity EnzymoPure™, ≥3,000 units/mg dry weight
Biochemical and Physiological Mechanisms Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30,000 Da. The enzyme catalyzes the hydration of carbon dioxide to carbonic acid. It is involved in vital physiological and pathological processes such as pH and CO2 h

Storage and Shipping

Concentration ≥3,000 units/mg dry weight
Storage Temp Store at 2-8°C
Shipped In Wet ice
CAS 9001-03-0
Enzyme Commission Number 4.2.1.1
Unit definition One Unit is determined by the electrometric method of Wilbur and Anderson (J. Biol. Chem., 176, 147 (1948)), in which the time required (in seconds) for a saturated CO2 solution to lower the pH of 0.02M Tris-HCl buffer from 8.3 to 6.3, at 0-4°C is determ

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot Number Certificate Type Date Item
C2507322 Certificate of Analysis Feb 27, 2025 C128742
C2507323 Certificate of Analysis Feb 27, 2025 C128742
E2431092 Certificate of Analysis May 22, 2024 C128742
E2431104 Certificate of Analysis May 22, 2024 C128742
E2431091 Certificate of Analysis May 22, 2024 C128742
E2431090 Certificate of Analysis May 22, 2024 C128742
E2431093 Certificate of Analysis May 22, 2024 C128742
D2403171 Certificate of Analysis Mar 11, 2024 C128742
C2318945 Certificate of Analysis Mar 10, 2023 C128742
J2311119 Certificate of Analysis Mar 10, 2023 C128742
F2518195 Certificate of Analysis Mar 10, 2023 C128742
F2518172 Certificate of Analysis Mar 10, 2023 C128742
C2318947 Certificate of Analysis Mar 10, 2023 C128742
B2314433 Certificate of Analysis Jun 18, 2022 C128742
G2207196 Certificate of Analysis Jun 18, 2022 C128742
G2207197 Certificate of Analysis Jun 18, 2022 C128742

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Citations of This Product

1. Meng-Meng Du, Yuan-Cheng Wang, Bao-Chang Sun, Yong Luo, Liang-Liang Zhang, Guang-Wen Chu, Hai-Kui Zou.  (2025)  Biocatalytic kinetics of the reaction between CO2 and tertiary amine using carbonic anhydrase.  Chemical Engineering and Processing-Process Intensification,  211  (110218). 

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