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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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C128742-10mg
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10mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$254.90
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|
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C128742-50mg
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50mg |
3
|
$869.90
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C128742-250mg
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250mg |
1
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$2,999.90
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| Product Name | Carbonic Anhydrase from bovine erythrocytes - ≥3,000 units/mg dry weight, high purity , CAS No.9001-03-0 |
|---|---|
| Synonyms | Carbonate Dehydratase | Carbonate Hydrolyase |
| Grade | EnzymoPure™ |
| Product Description |
Specificity: Blood CO2 transport and excretion is largely dependent on the rapid catalysis of the CO2 reactions within the erythrocyte by CA (Tufts et al. 2003). Bovine CA reversibly hydrates alkyl pyruvates and it exhibits hydratase activity toward a wide variety of substrates (Pocker et al. 1974, and Wells et al. 1975). Protein Accession Number: P00921 CATH Classification (v. 3.2.0): Class: Alpha Beta Architecture: Roll Topology: Carbonic Anhydrase II Molecular Weight: 29.0 kDa (Theoretical) 30 kDa (Lindskog et al. 1971) Optimal pH: 7.0-7.5 (Demir et al. 2000, and Tasgin et al. 2009) Isoelectric Point: 6.40 (Theoretical) Extinction Coefficient: 50,070 cm-1M-1 (Theoretical) E1%, 280 = 19.0 (Nyman and Lindskog 1964) Active Site Residues: Histidine (H63) Asparagine (N66) Lysine (K126) Activators: HPO42- (Rowlett et al. 1991) SO32- (Rowlett et al. 1991) Inhibitors: Monovalent anions (Lindskog et al. 1971, and Ward and Cull 1972) Sulfonates and sulfonamides (Pocker and Watamori 1973, and Binford et al. 1974) Imidazole (Edsall 1968) Applications: CO2 determination in blood Elimination of CO2 in reagents for acidity testing Carboxy group transfers Reduction reactions |
| Specifications & Purity | EnzymoPure™, ≥3,000 units/mg dry weight |
| Biochemical and Physiological Mechanisms | Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30,000 Da. The enzyme catalyzes the hydration of carbon dioxide to carbonic acid. It is involved in vital physiological and pathological processes such as pH and CO2 h |
| Concentration | ≥3,000 units/mg dry weight |
|---|---|
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| CAS | 9001-03-0 |
| Enzyme Commission Number | 4.2.1.1 |
| Unit definition | One Unit is determined by the electrometric method of Wilbur and Anderson (J. Biol. Chem., 176, 147 (1948)), in which the time required (in seconds) for a saturated CO2 solution to lower the pH of 0.02M Tris-HCl buffer from 8.3 to 6.3, at 0-4°C is determ |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 27, 2025 | C128742 | |
| Certificate of Analysis | Feb 27, 2025 | C128742 | |
| Certificate of Analysis | May 22, 2024 | C128742 | |
| Certificate of Analysis | May 22, 2024 | C128742 | |
| Certificate of Analysis | May 22, 2024 | C128742 | |
| Certificate of Analysis | May 22, 2024 | C128742 | |
| Certificate of Analysis | May 22, 2024 | C128742 | |
| Certificate of Analysis | Mar 11, 2024 | C128742 | |
| Certificate of Analysis | Mar 10, 2023 | C128742 | |
| Certificate of Analysis | Mar 10, 2023 | C128742 | |
| Certificate of Analysis | Mar 10, 2023 | C128742 | |
| Certificate of Analysis | Mar 10, 2023 | C128742 | |
| Certificate of Analysis | Mar 10, 2023 | C128742 | |
| Certificate of Analysis | Jun 18, 2022 | C128742 | |
| Certificate of Analysis | Jun 18, 2022 | C128742 | |
| Certificate of Analysis | Jun 18, 2022 | C128742 |
| 1. Meng-Meng Du, Yuan-Cheng Wang, Bao-Chang Sun, Yong Luo, Liang-Liang Zhang, Guang-Wen Chu, Hai-Kui Zou. (2025) Biocatalytic kinetics of the reaction between CO2 and tertiary amine using carbonic anhydrase. Chemical Engineering and Processing-Process Intensification, 211 (110218). |