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C18 Dihydroceramide (d18:0/18:0) - >99%, high purity , CAS No.2304-80-5

COA

Grade & Purity:

≥99%

Cas Number: 2304-80-5
Molecular Weight: 567.97
PubChem CID: 5283573
PubChem SID: 504763474

In stock

Item Number

N130689

Grouped product items
SKU	Size	Availability	Price	Qty
N130689-1mg	1mg	2	$137.90
N130689-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$480.90

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Lipid (87) Sphingolipids (98)

Basic Description

Synonyms	AKOS040754846 \| C18 Dihydroceramide \| C18 dihydro Ceramide (d18:0/18:0) \| N-stearoyldihydroceramide \| N-Stearoyldihydro-D-erythro-Sphingosine \| DB14706 \| C18 Dihydroceramide (d18:0/18:0) \| Cer(d18:0/18:0) \| C18-dihydro-Ceramide (N-stearoyl) \| Ceramide NS
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Dihydroceramides act as precursors for ceramides in the mammalian de-novo sphingolipid pathway. vitamin D supplementation increases plasma C18 dihydroceramide (C18-DHC) levels in type 2 diabetes mellitus (T2D) patients. Low serum concentration of C18-DHC
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	C18 Dihydroceramide (d18:0/18:0) or N-Stearoylsphinganine is a synthetic lipid. Acylation of sphinganine with stearoyl (FA-CoA with C18 acyl chain) by dihydro ceramide synthase 1, yields C18-dihydroceramide. application： C18 Dihydroceramide (d18:0/18:0) has been used as a standard for the quantitation of sphingolipid metabolites in adipose tissues by quadrupole time-of-flight (Q-TOF) mass spectrometry.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Sphingolipids
    - Subclass Ceramides

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Sphingolipids
Subclass	Ceramides
Intermediate Tree Nodes	Not available
Direct Parent	Long-chain ceramides
Alternative Parents	N-acyl amines Secondary carboxylic acid amides Secondary alcohols Primary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Long-chain ceramide - Fatty amide - N-acyl-amine - Fatty acyl - Carboxamide group - Secondary alcohol - Secondary carboxylic acid amide - Carboxylic acid derivative - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as long-chain ceramides. These are ceramides bearing a long chain fatty acid.
External Descriptors	N-acylsphinganines (dihydroceramides)
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504763474
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504763474
IUPAC Name	N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octadecanamide
INCHI	InChI=1S/C36H73NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h34-35,38-39H,3-33H2,1-2H3,(H,37,40)/t34-,35+/m0/s1
InChIKey	KZTJQXAANJHSCE-OIDHKYIRSA-N
Smiles	CCCCCCCCCCCCCCCCCC(=O)NC(CO)C(CCCCCCCCCCCCCCC)O
Isomeric SMILES	CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@@H](CCCCCCCCCCCCCCC)O
Molecular Weight	567.97
Reaxy-Rn	1809152
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1809152&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
B2525357	Certificate of Analysis	Feb 14, 2025	N130689
B2525358	Certificate of Analysis	Feb 14, 2025	N130689
B2525360	Certificate of Analysis	Feb 14, 2025	N130689
J2210627	Certificate of Analysis	Jul 13, 2023	N130689
J2210626	Certificate of Analysis	Jul 13, 2023	N130689

Chemical and Physical Properties

Molecular Weight	568.000 g/mol
XLogP3	14.500
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	33
Exact Mass	567.559 Da
Monoisotopic Mass	567.559 Da
Topological Polar Surface Area	69.600 Å²
Heavy Atom Count	40
Formal Charge	0
Complexity	498.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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