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BTK inhibitor 1 (Compound 27) - 10mM in DMSO, high purity , CAS No.2230724-66-8

COA

Grade & Purity:

10mM in DMSO

Cas Number: 2230724-66-8
Molecular Weight: 474.49
PubChem CID: 90125978

In stock

Item Number

B422680

Grouped product items
SKU	Size	Availability	Price	Qty
B422680-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$431.90

BTK Inhibitors

View related series

Compound libraries (12325) Non-receptor Tyrosine Kinase (643)

Basic Description

Synonyms	1,2,4-Oxadiazole-3-carboxamide,5-(1,1-dimethylethyl)-N-[[2-fluoro-4-[6-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]methyl]-
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information BTK inhibitor 1 (Compound 27) BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM. Targets BTK (Cell-free assay) 0.11 nM

Product Properties

ALogP	3.626
hba_count	7
HBD Count	2
Rotatable Bond	6

Names and Identifiers

IUPAC Name	5-tert-butyl-N-[[2-fluoro-4-[6-(1-methylpyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]methyl]-1,2,4-oxadiazole-3-carboxamide
INCHI	InChI=1S/C24H23FN8O2/c1-24(2,3)23-31-21(32-35-23)22(34)26-9-14-6-5-13(7-17(14)25)19-16-8-18(15-10-29-33(4)11-15)30-20(16)28-12-27-19/h5-8,10-12H,9H2,1-4H3,(H,26,34)(H,27,28,30)
InChIKey	XRNHJQXCSOAXLV-UHFFFAOYSA-N
Smiles	CC(C)(C)C1=NC(=NO1)C(=O)NCC2=C(C=C(C=C2)C3=C4C=C(NC4=NC=N3)C5=CN(N=C5)C)F
Isomeric SMILES	CC(C)(C)C1=NC(=NO1)C(=O)NCC2=C(C=C(C=C2)C3=C4C=C(NC4=NC=N3)C5=CN(N=C5)C)F
Molecular Weight	474.49
Reaxy-Rn	42314298
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=42314298&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility	95
DMSO(mM) Max Solubility	200.214967649476
Water(mg / mL) Max Solubility	＜1

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