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bpV(HOpic) - ≥95%, high purity , CAS No.722494-26-0

COA

Grade & Purity:

≥95%

Cas Number: 722494-26-0
Molecular Weight: 347.24
PubChem CID: 54692867

In stock

Item Number

B334661

Grouped product items
SKU	Size	Availability	Price
B334661-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$266.90
B334661-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$480.90
B334661-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,081.90
B334661-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,946.90
B334661-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,503.90

a protein PTP inhibitor

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PI3K/Akt/mTOR (765) PTEN (10)

Basic Description

Synonyms	Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) \| Bisperoxovanadium(HOpic) \| (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	bpV(HOpic) is a bisperoxo oxovanadate dipotassium salt coordinated to 5-hydroxypyridine-2-carboxylate. This vanadium compound has been shown to be a potent inhibitor of protein phosphotyrosine phosphatase (PTP) and PTEN, and has been described to act as an insulin mimetic. This compound has been shown to activate the insulin receptor kinase of hepatoma cells, stimulate lipogenesis in adipocytes, and to enhance PI3K/Akt signaling that could prevent ischemia-reperfusion (I/R) injury to the myocardium.

Names and Identifiers

Smiles	[K]OC(=O)C1=CC=C(O)C=[N]1[V]23(O[K])(OO2)OO3
Isomeric SMILES	C1=CC(=NC=C1[O-])C(=O)O.OO.OO.O=[V].[K+].[K+]
WGK Germany	3
PubChem CID	54692867
Molecular Weight	347.24

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Soluble in cold water (easily), and DMSO. Note: This product is not stable in water. Starts decomposition immediately after solubilization. Rate of decomposition is slower in dry DMSO.
Sensitivity	Light & Moisture sensitive

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