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Boeravinone B - ≥97.0%, high purity , CAS No.114567-34-9

    Grade & Purity:
  • ≥97%
In stock
Item Number
B647406
Grouped product items
SKU Size
Availability
Price Qty
B647406-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$350.90

Phenols Polyphenols Others

Basic Description

Synonyms Boeravinone B, analytical standard | HY-N2947 | SCHEMBL3320676 | BDBM50492740 | 6a,12a-Dehydro-6,9,11-trihydroxy-10-methylrotenone | 6,9,11-trihydroxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one | B0005-477333 | AKOS040762674 | MS-24546 | LMPK12060073 | bo
Specifications & Purity ≥97%
Biochemical and Physiological Mechanisms Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein , reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules duri
Storage Temp Protected from light,Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein , reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress.

In Vitro

Boeravinone B is also active against a methicillin-resistant S. aureus (MRSA) strain, which showed a fourfold reduction in the ciprofloxacin MIC. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Isoflavonoids
Subclass Rotenoids
Intermediate Tree Nodes Not available
Direct Parent Rotenones
Alternative Parents Isoflavones  Chromones  Pyranones and derivatives  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Vinylogous acids  Heteroaromatic compounds  Hemiacetals  Polyols  Oxacyclic compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Rotenone or derivatives - Isoflavone - Chromone - Benzopyran - 1-benzopyran - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Pyran - Benzenoid - Heteroaromatic compound - Vinylogous acid - Hemiacetal - Oxacycle - Polyol - Organoheterocyclic compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as rotenones. These are rotenoids with a structure based on a 6a,12a-dihydrochromeno[3,4-b]chromen-12(6H)-one skeleton.
External Descriptors Rotenoid flavonoids

Associated Targets(Human)

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 6,9,11-trihydroxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one
INCHI InChI=1S/C17H12O6/c1-7-9(18)6-11-13(14(7)19)15(20)12-8-4-2-3-5-10(8)23-17(21)16(12)22-11/h2-6,17-19,21H,1H3
InChIKey YVVDYYFGAWQOGB-UHFFFAOYSA-N
Smiles CC1=C(C2=C(C=C1O)OC3=C(C2=O)C4=CC=CC=C4OC3O)O
Isomeric SMILES CC1=C(C2=C(C=C1O)OC3=C(C2=O)C4=CC=CC=C4OC3O)O
Alternate CAS 114567-34-9
PubChem CID 14018348
MeSH Entry Terms 6,9,11-trihydroxy-10-methyl-6a,12a-dehydroretenoid;boeravinone B
Molecular Weight 312.27

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility DMSO : 50 mg/mL (160.12 mM; Need ultrasonic)
Molecular Weight 312.270 g/mol
XLogP3 2.400
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 0
Exact Mass 312.063 Da
Monoisotopic Mass 312.063 Da
Topological Polar Surface Area 96.200 Ų
Heavy Atom Count 23
Formal Charge 0
Complexity 543.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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