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BML-244 - ≥98%, high purity , CAS No.104062-70-6

    Grade & Purity:
  • ≥98%
In stock
Item Number
B275192
Grouped product items
SKU Size
Availability
Price Qty
B275192-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$80.90

Potent cathepsin K inhibitor

Basic Description

Synonyms tert-ButylN-[(2S)-1-oxohexan-2-yl]carbamate
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Highly potent, cell-permeable inhibitor of cathepsin K (IC 50 = 51 nM). Cell permeable and orally active.
Storage Temp Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Carbamic acids and derivatives
Direct Parent Carbamate esters
Alternative Parents Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Aldehydes  
Molecular Framework Aliphatic acyclic compounds
Substituents Carbamic acid ester - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aldehyde - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as carbamate esters. These are compounds containing an ester of carbamic acid with the general structure R2NC(=O)OR' (R' not H). They are esters of carbamic acids.
External Descriptors Not available

Names and Identifiers

IUPAC Name tert-butyl N-(1-oxohexan-2-yl)carbamate
INCHI InChI=1S/C11H21NO3/c1-5-6-7-9(8-13)12-10(14)15-11(2,3)4/h8-9H,5-7H2,1-4H3,(H,12,14)
InChIKey OBMGXPJNZKYOQY-UHFFFAOYSA-N
Smiles CCCCC(C=O)NC(=O)OC(C)(C)C
Isomeric SMILES CCCCC(C=O)NC(=O)OC(C)(C)C
Molecular Weight 215.29
Reaxy-Rn 5931453
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5931453&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Soluble in DMSO to 25 mM and in ethanol to 50 mM
Molecular Weight 215.290 g/mol
XLogP3 2.300
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 7
Exact Mass 215.152 Da
Monoisotopic Mass 215.152 Da
Topological Polar Surface Area 55.400 Ų
Heavy Atom Count 15
Formal Charge 0
Complexity 208.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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