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BLT-1 - 98%, high purity , CAS No.321673-30-7

COA

Grade & Purity:

≥98%

Cas Number: 321673-30-7
Molecular Weight: 241.4
PubChem CID: 9585336

In stock

Item Number

B412587

Grouped product items
SKU	Size	Availability	Price
B412587-10mg	10mg	3	$128.90
B412587-25mg	25mg	3	$272.90
B412587-50mg	50mg	3	$463.90
B412587-100mg	100mg	2	$787.90

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Basic Description

Synonyms	33M20 \| Probes2_000409 \| DTXSID80430563 \| Probes1_000008 \| Probes1_000093 \| Probes2_000390 \| BLT-1 \| E74752 \| EN300-68381 \| (2Z)-2-(2-hexylcyclopentylidene)hydrazinecarbothioamide \| EX-A4880 \| [(2-hexylcyclopentylidene)amino]thiourea \| Z275117012 \| SCHEMB
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	BLT-1 is an inhibitor of HDL receptor SR-BI. BLT-1 is primarily used for phosphorylation and dephosphorylation applications.Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	BLT-1 (Block lipid transport-1) has been used as an inhibitor of the SR-BI (scavenger receptor, class B, type I) mediated lipid transfer to determine if miR-223-3p export from polymorphonuclear neutrophils (PMNs) to high-density lipoproteins (HDLs) is dependent on SR-BI-mediated lipid flux. It has also been used as a SR-BI inhibitor to study the effect of HDL on osteocalcin (OCN) expression in monocyte cell lines through SR-B1. BLT-1 may be used to study cell signaling pathways that have role in cholesterol influx and efflux.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic nitrogen compounds
  - Class Organonitrogen compounds
    - Subclass Hydrazines and derivatives
      - Level5 Thiosemicarbazides
        Level6 Thiosemicarbazones

Kingdom	Organic compounds
Superclass	Organic nitrogen compounds
Class	Organonitrogen compounds
Subclass	Hydrazines and derivatives
Intermediate Tree Nodes	Thiosemicarbazides
Direct Parent	Thiosemicarbazones
Alternative Parents	Organosulfur compounds Hydrocarbon derivatives
Molecular Framework	Aliphatic homomonocyclic compounds
Substituents	Thiosemicarbazone - Hydrocarbon derivative - Organosulfur compound - Aliphatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as thiosemicarbazones. These are compounds containing the thiosemicarbazone functional group obtained by replacing the carbonyl group by a thiocarbonyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	[(E)-(2-hexylcyclopentylidene)amino]thiourea
INCHI	InChI=1S/C12H23N3S/c1-2-3-4-5-7-10-8-6-9-11(10)14-15-12(13)16/h10H,2-9H2,1H3,(H3,13,15,16)/b14-11+
InChIKey	OWGUSBISUVLUJF-SDNWHVSQSA-N
Smiles	CCCCCCC1CCCC1=NNC(=S)N
Isomeric SMILES	CCCCCCC\1CCC/C1=N\NC(=S)N
WGK Germany	3
Molecular Weight	241.4
Reaxy-Rn	11250336
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11250336&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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5 results found

Lot Number	Certificate Type	Date	Item
A2420068	Certificate of Analysis	Dec 19, 2023	B412587
A2420069	Certificate of Analysis	Dec 19, 2023	B412587
A2420070	Certificate of Analysis	Dec 19, 2023	B412587
A2420071	Certificate of Analysis	Dec 19, 2023	B412587
A2420072	Certificate of Analysis	Dec 19, 2023	B412587

Chemical and Physical Properties

Solubility	DMSO: ≥13 mg/mL
Molecular Weight	241.400 g/mol
XLogP3	3.300
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	241.161 Da
Monoisotopic Mass	241.161 Da
Topological Polar Surface Area	82.500 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	251.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

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