Basic Description

Synonyms	Bis(tetrakis(hydroxymethyl)phosphonium)sulfate (salt) \| TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE \| 5I8RSL9E6S \| Octakis(hydroxymethyl)phosphonium sulfate \| THPS
Specifications & Purity	75% in water
Shipped In	Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic salts
  - Class Organic sulfate salts

Kingdom	Organic compounds
Superclass	Organic salts
Class	Organic sulfate salts
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Organic sulfate salts
Alternative Parents	Tetraalkylphosphonium compounds Organic sulfuric acids and derivatives Organopnictogen compounds Organooxygen compounds Organic zwitterions Organic oxides Hydrocarbon derivatives
Molecular Framework	Not available
Substituents	Organic sulfate salt - Tetraalkylphosphonium compound - Organic sulfuric acid or derivatives - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic zwitterion - Organophosphorus compound - Organooxygen compound - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as organic sulfate salts. These are organic compounds containing a sulfate ion.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504753608
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504753608
IUPAC Name	tetrakis(hydroxymethyl)phosphanium;sulfate
INCHI	InChI=1S/2C4H12O4P.H2O4S/c25-1-9(2-6,3-7)4-8;1-5(2,3)4/h25-8H,1-4H2;(H2,1,2,3,4)/q2*+1;/p-2
InChIKey	YIEDHPBKGZGLIK-UHFFFAOYSA-L
Smiles	C(O)[P+](CO)(CO)CO.C(O)[P+](CO)(CO)CO.[O-]S(=O)(=O)[O-]
Isomeric SMILES	C(O)[P+](CO)(CO)CO.C(O)[P+](CO)(CO)CO.[O-]S(=O)(=O)[O-]
WGK Germany	3
RTECS	TA2570000
UN Number	2922
Packing Group	I
Molecular Weight	406.28
Beilstein	8521357
Reaxy-Rn	6458412
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6458412&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot Number	Certificate Type	Date	Item
G2416055	Certificate of Analysis	May 13, 2024	B101527
E2522063	Certificate of Analysis	May 13, 2024	B101527
B2514007	Certificate of Analysis	May 13, 2024	B101527
E2421179	Certificate of Analysis	May 13, 2024	B101527
E2421183	Certificate of Analysis	May 13, 2024	B101527
E2421180	Certificate of Analysis	May 13, 2024	B101527
E2421189	Certificate of Analysis	May 13, 2024	B101527
E2421413	Certificate of Analysis	May 13, 2024	B101527
E2421414	Certificate of Analysis	May 13, 2024	B101527
C2522055	Certificate of Analysis	May 13, 2024	B101527
L1911005	Certificate of Analysis	Sep 08, 2023	B101527
H2224013	Certificate of Analysis	Jul 26, 2022	B101527
H2224014	Certificate of Analysis	Jul 26, 2022	B101527
H2224015	Certificate of Analysis	Jul 26, 2022	B101527
H2224011	Certificate of Analysis	Jul 26, 2022	B101527
H2224012	Certificate of Analysis	Jul 26, 2022	B101527

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Chemical and Physical Properties

Molecular Weight	406.280 g/mol
XLogP3
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	8
Exact Mass	406.046 Da
Monoisotopic Mass	406.046 Da
Topological Polar Surface Area	250.000 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	118.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Fengguo Tian, Jianzhi Qiao, Wentian Zheng, Yang Lei, Shengtao Jiang, Yanbiao Liu. (2023) Flow-through electrochemical organophosphorus degradation and phosphorus recovery: The essential role of chlorine radical. ENVIRONMENTAL RESEARCH, 236 (116867).
2. Lilong Zhou, Shenghao Wang, Zhengjie Li, Xuepu Cao, Runjing Liu, Jimmy Yun. (2023) Simultaneously removal of phosphorous and COD for purification of organophosphorus wastewater by catalytic ozonation over CaO. Journal of Water Process Engineering, 51 (103397).
3. Erli Yang, Hong Yang, Zhenqiang Ning, Yanfeng Fang, Mengyuan Chen, Yongjun Zheng, Wenhua Xu, Guoqiu Wu, Yuanjian Zhang, Yanfei Shen. (2022) Construction of Carbon Dots with Wavelength-Tunable Electrochemiluminescence and Enhanced Efficiency. ANALYTICAL CHEMISTRY, 94 (47): (16510–16518).
4. Jiang Ouyang, Qingyue Bu, Na Tao, Mingkai Chen, Haijun Liu, Jun Zhou, Jinggong Liu, Bo Deng, Na Kong, Xingcai Zhang, Tianfeng Chen, Yihai Cao, Wei Tao. (2022) A facile and general method for synthesis of antibiotic-free protein-based hydrogel: Wound dressing for the eradication of drug-resistant bacteria and biofilms. Bioactive Materials, 18 (446).
5. Guofeng Ye, Siqi Huo, Cheng Wang, Qiu Shi, Lingfeng Yu, Zhitian Liu, Zhengping Fang, Hao Wang. (2021) A novel hyperbranched phosphorus-boron polymer for transparent, flame-retardant, smoke-suppressive, robust yet tough epoxy resins. COMPOSITES PART B-ENGINEERING, 227 (109395).
6. Kang Zhang, Chao Ma, Yapeng Zheng, Feng Zhou, Yuling Xiao, Weiyi Xing, Yuan Hu. (2021) A novel coating of hyperbranched poly(urethane-phosphine oxide) for poly(methyl methacrylate) with high fire safety, excellent adhesion and transparency. PROGRESS IN ORGANIC COATINGS, 161 (106481).
7. Gang Tang, Mengru Liu, Dan Deng, Ruiqing Zhao, Xinliang Liu, Yadong Yang, Sujie Yang, Xiuyu Liu. (2021) Phosphorus-containing soybean oil-derived polyols for flame-retardant and smoke-suppressant rigid polyurethane foams. POLYMER DEGRADATION AND STABILITY, 191 (109701).
8. Yao Yuan, Yongqian Shi, Bin Yu, Jing Zhan, Yan Zhang, Lei Song, Chao Ma, Yuan Hu. (2020) Facile synthesis of aluminum branched oligo(phenylphosphonate) submicro-particles with enhanced flame retardance and smoke toxicity suppression for epoxy resin composites. JOURNAL OF HAZARDOUS MATERIALS, 381 (121233).
9. Junling Wang, Chao Ma, Peilong Wang, Shuilai Qiu, Wei Cai, Yuan Hu. (2018) Ultra-low phosphorus loading to achieve the superior flame retardancy of epoxy resin. POLYMER DEGRADATION AND STABILITY, 149 (119).
10. Chao Ma, Bin Yu, Ningning Hong, Yang Pan, Weizhao Hu, Yuan Hu. (2016) Facile Synthesis of a Highly Efficient, Halogen-Free, and Intumescent Flame Retardant for Epoxy Resins: Thermal Properties, Combustion Behaviors, and Flame-Retardant Mechanisms. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 55 (41): (10868–10879).
11. Ying Lin, Bin Yu, Xin Jin, Lei Song, Yuan Hu. (2016) Study on thermal degradation and combustion behavior of flame retardant unsaturated polyester resin modified with a reactive phosphorus containing monomer. RSC Advances, 6 (55): (49633-49642).
12. Liangyuan Qi, Wei Cai, Jiajun Li, Tianyang Cui, Liang Chen, Jing Gao, Bin Fei, Yuan Hu, Lei Song, Zhou Gui, Weiyi Xing. (2024) Advanced Janus Coatings for Thermal Management and Synergistic Flame Retardancy in Textiles. Journal of Materials Chemistry A,
13. Yueqi Yang, Saizheng Wang, Siqi Wang, Chang Wang, Yunhong Jiao, Hongmei Liu, Haiyun Ma. (2024) Biomimetic aerogel coatings for flexible polyurethane foams with superior flame retardancy, mechanical flexibility and antibacterial properties. PROGRESS IN ORGANIC COATINGS, 196 (108702).
14. Wang Siqi, Yang Yueqi, Wang Chang, Jiao Yunhong, Wang Chunzheng, Ma Haiyun. (2024) Dual cross-linked alginate/lignosulfonate—based aerogel with robust flame retardancy and antibacterial property. CELLULOSE, 31 (14): (8787-8803).
15. Jiahao Sun, Shihang Lu, Ming Cheng, Nianting Xue, Shiqiang Chen, Guangzhou Liu, Yuanyuan Gao, Li Lai, Wenwen Dou. (2025) Novel peptides based on sea squirt as biocide enhancers to mitigate biocorrosion of EH36 steel. BIOELECTROCHEMISTRY, (108890).

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SKU	Size	Availability	Price
B101527-100ml	100ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$26.90
B101527-250ml	250ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$54.90
B101527-500ml	500ml	2	$86.90

Bis[tetrakis(hydroxymethyl)phosphonium] sulfate solution - 75% in water, high purity , CAS No.55566-30-8