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Benzo(b)fluoranthene D12 - 10ng/ul in cyclohexane, high purity , CAS No.205-99-2

    Grade & Purity:
  • 10ng/ul in cyclohexane
In stock
Item Number
B141493
Grouped product items
SKU Size
Availability
Price Qty
B141493-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$412.90

Basic Description

Synonyms NSC 89265 | 3,4-Benz(e)acephenanthrylene | 3,4-Benzofluoranthrene | benz[e]acephenanthrylen | BENZO(B)FLUORANTHENE [IARC] | CCRIS 72 | FTOVXSOBNPWTSH-UHFFFAOYSA-N | NCGC00090866-03 | DTXCID903907 | BRN 1872553 | DTXSID0023907 | 4,5-Benzofluoranthene | B(b
Specifications & Purity 10ng/ul in cyclohexane
Storage Temp Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

A polycyclic aromatic hydrocarbon.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Phenanthrenes and derivatives
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Phenanthrenes and derivatives
Alternative Parents Naphthalenes  Aromatic hydrocarbons  Polycyclic hydrocarbons  Unsaturated hydrocarbons  
Molecular Framework Aromatic homopolycyclic compounds
Substituents Phenanthrene - Naphthalene - Aromatic hydrocarbon - Polycyclic hydrocarbon - Unsaturated hydrocarbon - Hydrocarbon - Aromatic homopolycyclic compound
Description This compound belongs to the class of organic compounds known as phenanthrenes and derivatives. These are polycyclic compounds containing a phenanthrene moiety, which is a tricyclic aromatic compound with three non-linearly fused benzene.
External Descriptors ortho- and peri-fused polycyclic arene

Associated Targets(Human)

ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TNF Tclin TNF-alpha (1897 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AHR Tclin Aryl hydrocarbon receptor (1071 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CASP1 Tchem Caspase-1 (6235 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name pentacyclo[10.7.1.02,7.08,20.013,18]icosa-1(19),2(7),3,5,8(20),9,11,13,15,17-decaene
INCHI InChI=1S/C20H12/c1-2-7-14-13(6-1)12-19-16-9-4-3-8-15(16)18-11-5-10-17(14)20(18)19/h1-12H
InChIKey FTOVXSOBNPWTSH-UHFFFAOYSA-N
Smiles C1=CC=C2C3=C4C(=CC=C3)C5=CC=CC=C5C4=CC2=C1
Isomeric SMILES C1=CC=C2C3=C4C(=CC=C3)C5=CC=CC=C5C4=CC2=C1
WGK Germany 3
UN Number 2811
Packing Group I
Molecular Weight 252.31
Beilstein 1872553
Reaxy-Rn 1872553
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1872553&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Flash Point(°C) -18 °C
Boil Point(°C) 481°C
Melt Point(°C) 163-165°C
Molecular Weight 252.300 g/mol
XLogP3 6.400
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 0
Rotatable Bond Count 0
Exact Mass 252.094 Da
Monoisotopic Mass 252.094 Da
Topological Polar Surface Area 0.000 Ų
Heavy Atom Count 20
Formal Charge 0
Complexity 372.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Shaolin Xie, Bing Yang, Siying Li, Liangjun Ge, Min Li, Qingshi Chen, Xian Qing, Jixing Zou.  (2023)  Generation and application of a novel transgenic zebrafish line Tg(GAcyp1a:eGFP/Luc) as an in vivo assay to sensitive and specific monitoring of DLCs in the environment.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  264  (115471). 
2. Liu Li, Peng Maomin, Xu Ke, Xia Hong, Peng Xitian, Peng Lijun, Zhang Jin Z..  (2023)  Molecularly imprinted fluorescence assay based on lead halide perovskite quantum dots for determination of benzo(a)pyrene.  MICROCHIMICA ACTA,  190  (10): (1-11). 
3. Yuanji Gao, Hongru Feng, Bing Xia, Lei He, Congling Yang, Lijuan Zhao, Yuanjiang Pan.  (2023)  Ultrasensitive and Green Bubbling Extraction Strategies: An Extensible Solvent-Free Re-Enrichment Approach for Ultratrace Pollutants in Aqueous Samples.  ANALYTICAL CHEMISTRY,  95  (36): (13683–13689). 
4. Guanqing Jiang, Xu Song, Jiaying Xie, Tongxing Shi, Qiaoyuan Yang.  (2023)  Polycyclic aromatic hydrocarbons (PAHs) in ambient air of Guangzhou city: Exposure levels, health effects and cytotoxicity.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  262  (115308). 
5. Qing Liu, Chao Yan, Yan Wang.  (2023)  Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC.  MOLECULES,  28  (8): (3542). 
6. Shaolin Xie, Yongyong Feng, Aiguo Zhou, Zhiyuan Lu, JixingZou.  (2023)  Comparative analysis of two new zebrafish models: The cyp1a low-expression line and cyp1a knockout line under PAHs exposure.  GENE,  869  (147391). 
7. Yuan Peng, Si-Yuan He, Fang-Huan Wang, Hao-Bo Zheng, Zhe Meng.  (2022)  Determination of polycyclic aromatic hydrocarbons in edible oil by magnetic solid phase extraction based on a mesoporous molybdenum disulfide/graphite prior to gas chromatography-mass spectrometry.  MICROCHEMICAL JOURNAL,  183  (108146). 
8. Yu Tian, Zhigang Xu, Zhimin Liu, Xiaoxi Si, Fengmei Zhang, Wei Jiang.  (2022)  Fe3O4@SiO2@VAN Nanoadsorbent Followed by GC-MS for the Determination of Polycyclic Aromatic Hydrocarbons at Ultra-Trace Levels in Environmental Water Samples.  Nanomaterials,  12  (17): (2921). 
9. Li Zhansheng, Zhao Hongxia, Li Xintong, Bekele Tadiyose Girma.  (2022)  Characteristics and sources of environmentally persistent free radicals in PM2.5 in Dalian, Northeast China: correlation with polycyclic aromatic hydrocarbons.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  29  (17): (24612-24622). 
10. Qingqing Cao, Siqi Lu, Wenjun Yin, Yan Kang, Naihao Yang, Yudong Hou, Zizhang Guo.  (2021)  Removal Performance and Mechanism of Benzo(b)Fluorathene Using MnO2 Nanoflower/Graphene Oxide Composites.  Materials,  14  (16): (4402). 
11. Jun Mu, Qingxue Leng, Guangfeng Yang, Baikang Zhu.  (2021)  Anaerobic degradation of high-concentration polycyclic aromatic hydrocarbons (PAHs) in seawater sediments.  MARINE POLLUTION BULLETIN,  167  (112294). 
12. Yilin Zhang, Dongwei Liu, Zhangsuo Liu.  (2020)  The benzo[b]fluoranthene in the atmospheric fine particulate matter induces mouse glomerular podocytes injury via inhibition of autophagy.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  195  (110403). 
13. Dan Han, Dongya Ni, Qing Zhou, Jingjing Ji, Yanqin Lv, Yanfei Shen, Songqin Liu, Yuanjian Zhang.  (2019)  Harnessing Photoluminescent Properties of Carbon Nitride Nanosheets in a Hierarchical Matrix.  ADVANCED FUNCTIONAL MATERIALS,  29  (49): (1905576). 
14. Qing Wang, Jiaxin Lian, Zhongdan Hua, Ying Yang, Ying Li, Xiuwen Hao, Yaxin Cao, Xianqi Zeng.  (2018)  Hybrid nanomaterial based on magnetic multiwalled carbon nanotube-octadecylphosphonic acid modified zirconia for magnetic solid-phase extraction of polycyclic aromatic hydrocarbons from edible oils.  Analytical Methods,  10  (46): (5516-5523). 
15. Zhou Xiu-Jie, Zhang Li-Shun, Song Wen-Fang, Huang Yan-Ping, Liu Zhao-Sheng.  (2018)  A polymer monolith incorporating stellate mesoporous silica nanospheres for use in capillary electrochromatography and solid phase microextraction of polycyclic aromatic hydrocarbons and organic small molecules.  MICROCHIMICA ACTA,  185  (9): (1-10). 
16. Qian Xiang, Guoqiang Shan, Wei Wu, Hangbiao Jin, Lingyan Zhu.  (2018)  Measuring log Kow coefficients of neutral species of perfluoroalkyl carboxylic acids using reversed-phase high-performance liquid chromatography.  ENVIRONMENTAL POLLUTION,  242  (1283). 
17. Bin Qiao, Yansong Li, Pan Hu, Yu Sun, Zhaozhao Si, Shiying Lu, Honglin Ren, Zengshan Liu, Ying Zhang, Lei Meng, Yu Zhou.  (2018)  EuNPs-MAb fluorescent probe based immunochromatographic strip for rapid and sensitive detection of fluorene.  SENSORS AND ACTUATORS B-CHEMICAL,  262  (221). 
18. Yong Li, Ling Long, Jing Ge, Li-xuan Yang, Jin-jin Cheng, Ling-xiang Sun, Changying Lu, Xiang-yang Yu.  (2017)  Presence, distribution and risk assessment of polycyclic aromatic hydrocarbons in rice-wheat continuous cropping soils close to five industrial parks of Suzhou, China.  CHEMOSPHERE,  184  (753). 
19. Li-Shun Zhang, Qing-Li Zhao, Xin-Xin Li, Xi-Xi Li, Yan-Ping Huang, Zhao-Sheng Liu.  (2016)  Green synthesis of mesoporous molecular sieve incorporated monoliths using room temperature ionic liquid and deep eutectic solvents.  TALANTA,  161  (660). 
20. Li-Shun Zhang, Pei-Yao Du, Wen Gu, Qing-Li Zhao, Yan-Ping Huang, Zhao-Sheng Liu.  (2016)  Monolithic column incorporated with lanthanide metal-organic framework for capillary electrochromatography.  JOURNAL OF CHROMATOGRAPHY A,  1461  (171). 
21. Cuicui Liu, Xiaoli Zhang, Limei Li, Jingcheng Cui, Yu-e Shi, Le Wang, Jinhua Zhan.  (2015)  Silver nanoparticle aggregates on metal fibers for solid phase microextraction–surface enhanced Raman spectroscopy detection of polycyclic aromatic hydrocarbons.  ANALYST,  140  (13): (4668-4675). 
22. Ling Xia,Yuanyuan He,Xiaohua Xiao,Gongke Li.  (2019-04-27)  An online field-assisted micro-solid-phase extraction device coupled with high-performance liquid chromatography for the direct analysis of solid samples..  Analytical and bioanalytical chemistry,  411  ((18)): (4073-4084). 
23. Qing Liu,Kevin Yan,Qiaomei Chen,Soumia Cheddah,Lin Shen,Han Xiao,Yan Wang,Chao Yan.  (2018-12-28)  Preparation of silica colloidal crystal column and its application in pressurized capillary electrochromatography..  Journal of chromatography. A,  1587  (172-179). 
24. Zifang Peng, Yanhao Zhang, Yide Dong, Wuduo Zhao, Jian Mao, Qidong Zhang, Gangfeng Ouyang, Shusheng Zhang, Jianping Xie.  (2025)  A cheap 3D-printed boron, nitrogen, sulfur-MXene quantum dots-based target plate for multi-dimensional MALDI MS imaging of small-molecule environmental pollutants.  CHEMICAL ENGINEERING JOURNAL,  507  (160596). 
25. Qian Zhang, Xinyan Xu, Chenzhuo Song, Dengke Zhang, Yi Kong, Xinyi Cui.  (2024)  Effect of UV exposure and natural aging on the in vitro PAHs bioaccessibility associated with tire wear particles in soil.  SCIENCE OF THE TOTAL ENVIRONMENT,  951  (175751). 
26. Xintong Li, Baocheng Qu, Jingyao Wang, Hongxia Zhao.  (2024)  Photoformation of Environmentally Persistent Free Radicals During Phototransformation of Poly-Cyclic Aromatic Hydrocarbons (PAHs) on Particles in an Aqueous Solution: The Hydrogenation of PAHs and Effect of Co-Existing Water Matrix Factors.  Toxics,  12  (11): (796). 
27. Xintong Li, Baocheng Qu, Jingyao Wang, Hongxia Zhao.  (2024)  Phototransformation of tetrabromobisphenol A bis (allyl ether) in an aqueous solution: Role of environmentally persistent free radicals.  CHEMOSPHERE,  365  (143342). 

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