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Belotecan Hydrochloride - 98％, high purity , CAS No.213819-48-8

COA

Grade & Purity:

≥98%

Cas Number: 213819-48-8
Molecular Weight: 469.96
PubChem CID: 6918340
PubChem SID: 504764363

In stock

Item Number

B330794

Grouped product items
SKU	Size	Availability	Price
B330794-10mg	10mg	3	$117.90
B330794-25mg	25mg	3	$187.90
B330794-50mg	50mg	2	$266.90
B330794-100mg	100mg	2	$375.90

a novel camptothecin-derivative anti-tumor agent

View related series

Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Lipid PEG (395) Topoisomerase (150)

Basic Description

Synonyms	Belotecan hydrochloride \| Camtobell hydrochloride \| DTXSID60175647 \| MFCD00438683 \| Q27231424 \| Belotecan HCl \| BELOTECAN HYDROCHLORIDE [MI] \| Belotecan Hydrochloride [USAN] \| CKD-602; belotecan hydrochloride \| (19S)-19-ethyl-19-hydroxy-10-[2-(propan-2-yl
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Application： Belotecan Hydrochloride is a novel camptothecin-derivative anti-tumor agent. CKD-602-related toxicities induced by IV infusion administration have not yet been evaluated, although the drug is more widely used in clinical settings.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Alkaloids and derivatives
  - Class Camptothecins

Kingdom	Organic compounds
Superclass	Alkaloids and derivatives
Class	Camptothecins
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Camptothecins
Alternative Parents	Quinolines and derivatives Pyranopyridines Pyridinones Aralkylamines Benzenoids Tertiary alcohols Heteroaromatic compounds Amino acids and derivatives Lactones Lactams Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Azacyclic compounds Dialkylamines Carbonyl compounds Hydrocarbon derivatives Hydrochlorides Organic oxides
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Camptothecin - Pyranopyridine - Quinoline - Pyridinone - Aralkylamine - Pyridine - Benzenoid - Heteroaromatic compound - Tertiary alcohol - Amino acid or derivatives - Carboxylic acid ester - Lactam - Lactone - Oxacycle - Azacycle - Carboxylic acid derivative - Organoheterocyclic compound - Secondary aliphatic amine - Secondary amine - Monocarboxylic acid or derivatives - Carbonyl group - Amine - Organic nitrogen compound - Hydrochloride - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Alcohol - Organic oxide - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as camptothecins. These are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring).
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504764363
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504764363
IUPAC Name	(19S)-19-ethyl-19-hydroxy-10-[2-(propan-2-ylamino)ethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione;hydrochloride
INCHI	InChI=1S/C25H27N3O4.ClH/c1-4-25(31)19-11-21-22-17(12-28(21)23(29)18(19)13-32-24(25)30)15(9-10-26-14(2)3)16-7-5-6-8-20(16)27-22;/h5-8,11,14,26,31H,4,9-10,12-13H2,1-3H3;1H/t25-;/m0./s1
InChIKey	SJKBXKKZBKCHET-UQIIZPHYSA-N
Smiles	CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)CCNC(C)C)O.Cl
Isomeric SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)CCNC(C)C)O.Cl
PubChem CID	6918340
Molecular Weight	469.96

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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6 results found

Lot Number	Certificate Type	Date	Item
A2211702	Certificate of Analysis	Oct 23, 2024	B330794
A2211709	Certificate of Analysis	Oct 23, 2024	B330794
L2203289	Certificate of Analysis	Oct 09, 2022	B330794
L2203292	Certificate of Analysis	Oct 09, 2022	B330794
L2203291	Certificate of Analysis	Oct 09, 2022	B330794
L2203290	Certificate of Analysis	Oct 09, 2022	B330794

Chemical and Physical Properties

Sensitivity	Moisture sensitive
Melt Point(°C)	>218° C (dec.)
Molecular Weight	470.000 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	469.177 Da
Monoisotopic Mass	469.177 Da
Topological Polar Surface Area	91.800 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	865.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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