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BAM 15 - ≥98%(HPLC), high purity , CAS No.210302-17-3

    Grade & Purity:
  • ≥98%(HPLC)
In stock
Item Number
B287299
Grouped product items
SKU Size
Availability
Price Qty
B287299-5mg
5mg
3
$59.90
B287299-10mg
10mg
3
$99.90
B287299-25mg
25mg
2
$179.90
B287299-50mg
50mg
2
$299.90
B287299-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$479.90

Mitochondrial protonophore uncoupler

Basic Description

Synonyms BAM 15 | N-[6-(2-Fluoroanilino)[1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl]-N-(2-fluorophenyl)amine
Specifications & Purity ≥98%(HPLC)
Biochemical and Physiological Mechanisms BAM15 can increase mitochondrial respiration rate and has lower cytotoxicity compared to other protonated uncoupling agents such as carbonyl cyanide p-trifluoromethoxyphenylhydrazone. Blocked signaling of oncogenic MAPK (mitogen activated protein kinase)
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Aniline and substituted anilines
Intermediate Tree Nodes Not available
Direct Parent Aniline and substituted anilines
Alternative Parents Fluorobenzenes  Aminopyrazines  Imidolactams  Aryl fluorides  Heteroaromatic compounds  Furazans  Secondary amines  Azacyclic compounds  Organopnictogen compounds  Organofluorides  Organic oxygen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Aniline or substituted anilines - Aminopyrazine - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Pyrazine - Imidolactam - Azole - Furazan - Heteroaromatic compound - Oxadiazole - Azacycle - Secondary amine - Organoheterocyclic compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic nitrogen compound - Hydrocarbon derivative - Amine - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as aniline and substituted anilines. These are organic compounds containing an aminobenzene moiety.
External Descriptors Not available

Associated Targets(Human)

MCF7 (126967 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Escherichia coli (133304 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504759279
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504759279
IUPAC Name 5-N,6-N-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
INCHI InChI=1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24)
InChIKey OEGJBRZAJRPPHL-UHFFFAOYSA-N
Smiles C1=CC=C(C(=C1)NC2=NC3=NON=C3N=C2NC4=CC=CC=C4F)F
Isomeric SMILES C1=CC=C(C(=C1)NC2=NC3=NON=C3N=C2NC4=CC=CC=C4F)F
Molecular Weight 340.29
Reaxy-Rn 8162244
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8162244&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number Certificate Type Date Item
C2210424 Certificate of Analysis Dec 18, 2024 B287299
C2210426 Certificate of Analysis Dec 18, 2024 B287299
C2210425 Certificate of Analysis Dec 18, 2024 B287299
C2210430 Certificate of Analysis Dec 18, 2024 B287299
F2427186 Certificate of Analysis Jun 03, 2024 B287299
F2427187 Certificate of Analysis Jun 03, 2024 B287299
C2210450 Certificate of Analysis Feb 11, 2022 B287299

Chemical and Physical Properties

Solubility Solvent:DMSO, Max Conc. mg/mL: 34.03, Max Conc. mM: 100
Molecular Weight 340.290 g/mol
XLogP3 3.700
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 4
Exact Mass 340.088 Da
Monoisotopic Mass 340.088 Da
Topological Polar Surface Area 88.800 Ų
Heavy Atom Count 25
Formal Charge 0
Complexity 409.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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