Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
B287299-5mg
|
5mg |
3
|
$59.90
|
|
|
B287299-10mg
|
10mg |
3
|
$99.90
|
|
|
B287299-25mg
|
25mg |
2
|
$179.90
|
|
|
B287299-50mg
|
50mg |
2
|
$299.90
|
|
|
B287299-100mg
|
100mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$479.90
|
|
Mitochondrial protonophore uncoupler
| Synonyms | BAM 15 | N-[6-(2-Fluoroanilino)[1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl]-N-(2-fluorophenyl)amine |
|---|---|
| Specifications & Purity | ≥98%(HPLC) |
| Biochemical and Physiological Mechanisms | BAM15 can increase mitochondrial respiration rate and has lower cytotoxicity compared to other protonated uncoupling agents such as carbonyl cyanide p-trifluoromethoxyphenylhydrazone. Blocked signaling of oncogenic MAPK (mitogen activated protein kinase) |
| Storage Temp | Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Aniline and substituted anilines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aniline and substituted anilines |
| Alternative Parents | Fluorobenzenes Aminopyrazines Imidolactams Aryl fluorides Heteroaromatic compounds Furazans Secondary amines Azacyclic compounds Organopnictogen compounds Organofluorides Organic oxygen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Aniline or substituted anilines - Aminopyrazine - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Pyrazine - Imidolactam - Azole - Furazan - Heteroaromatic compound - Oxadiazole - Azacycle - Secondary amine - Organoheterocyclic compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic nitrogen compound - Hydrocarbon derivative - Amine - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as aniline and substituted anilines. These are organic compounds containing an aminobenzene moiety. |
| External Descriptors | Not available |
|
|
|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504759279 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504759279 |
| IUPAC Name | 5-N,6-N-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine |
| INCHI | InChI=1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24) |
| InChIKey | OEGJBRZAJRPPHL-UHFFFAOYSA-N |
| Smiles | C1=CC=C(C(=C1)NC2=NC3=NON=C3N=C2NC4=CC=CC=C4F)F |
| Isomeric SMILES | C1=CC=C(C(=C1)NC2=NC3=NON=C3N=C2NC4=CC=CC=C4F)F |
| Molecular Weight | 340.29 |
| Reaxy-Rn | 8162244 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8162244&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 18, 2024 | B287299 | |
| Certificate of Analysis | Dec 18, 2024 | B287299 | |
| Certificate of Analysis | Dec 18, 2024 | B287299 | |
| Certificate of Analysis | Dec 18, 2024 | B287299 | |
| Certificate of Analysis | Jun 03, 2024 | B287299 | |
| Certificate of Analysis | Jun 03, 2024 | B287299 | |
| Certificate of Analysis | Feb 11, 2022 | B287299 |
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 34.03, Max Conc. mM: 100 |
|---|---|
| Molecular Weight | 340.290 g/mol |
| XLogP3 | 3.700 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 4 |
| Exact Mass | 340.088 Da |
| Monoisotopic Mass | 340.088 Da |
| Topological Polar Surface Area | 88.800 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 409.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Starting at $62.90