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Balofloxacin - 10mM in DMSO, high purity , CAS No.127294-70-6(DMSO)
Topo II Selective Inhibitors | Activators
Basic Description
| Synonyms |
Q-35 | 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidinyl]-4-oxo-3-quinolinecarboxylic acid |
| Specifications & Purity |
10mM in DMSO |
| Biochemical and Physiological Mechanisms |
Balofloxacin (Q-35) is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase. |
| Storage Temp |
Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Information Balofloxacin (Q-35) is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.
In vitro
In vivo
Cell Data
cell lines：COS-7 Concentrations： Incubation Time： Powder Purity:≥99%
|
Product Properties
| ALogP |
-0.615 |
| hba_count |
3 |
| HBD Count |
1 |
| Rotatable Bond |
5 |
Names and Identifiers
| Smiles |
CNC1CCCN(C1)C2=C(OC)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O |
| Molecular Weight |
389.42 |
| Reaxy-Rn |
8362117 |
| Reaxys-RN_link_address |
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8362117&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
| Solubility |
Solubility (25°C) In vitro DMSO: 47 mg/mL (201.98 mM); Ethanol: 14 mg/mL (60.16 mM); Water: Insoluble; |
| DMSO(mg / mL) Max Solubility |
5 |
| DMSO(mM) Max Solubility |
12.84 |
| Water(mg / mL) Max Solubility |
<1 |
Citations of This Product
|
1.
Jia-Yu Zeng, Yu-Qi Liang, Yan-Ni Wu, Xiao-Yi Wu, Jia-Ping Lai, Hui Sun.
(2022)
Synthesis and application of novel N, Si-carbon dots for the ratiometric fluorescent monitoring of the antibiotic balofloxacin in tablets and serum.
RSC Advances,
12
(45):
(29585-29594).
|
|
2.
Fan Zhang, Xiangsheng Han, Chuanlong Guo, Hui Yang, Jun Wang, Xiaochen Wu.
(2021)
Fibrous aramid hydrogel supported antibacterial agents for accelerating bacterial-infected wound healing.
Materials Science & Engineering C-Materials for Biological Applications,
121
(111833).
|
|
3.
Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang.
(2018)
Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters.
SCIENCE OF THE TOTAL ENVIRONMENT,
645
(482).
|
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3 Citations