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[bAla8]-Neurokinin A(4-10), CAS No.122063-01-8

COA

Grade & Purity:

≥98%

In stock

Item Number

B286633

Grouped product items
SKU	Size	Availability	Price
B286633-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$307.90
B286633-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$867.90
B286633-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,445.90
B286633-25mg	25mg	2	$3,253.90

NK2agonist

View related series

Class A GPCR (4138) GPCR/G Protein (3172) Neurokinin Receptor (49) Neuronal Signaling (3320)

Basic Description

Product Name	[bAla8]-Neurokinin A(4-10), CAS No.122063-01-8
Synonyms	MEN 10210 \| [beta-Ala8] Neurokinin A (4-10) \| (5S,8R,15S,18R,21S,24S)-24-amino-18-benzyl-5-carbamoyl-21-(hydroxymethyl)-8-isobutyl-15-isopropyl-7,10,14,17,20,23-hexaoxo-2-thia-6,9,13,16,19,22-hexaazahexacosan-26-oic acid
Product Description	[bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist. Soluble to 0.67 mg/ml in 30% acetonitrile / sterile water. Asp-Ser-Phe-Val-{Bal}-Leu-Met-NH2.
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	NK2receptor agonist (pD2= 6.91). Produces bladder contraction and bronchospasm in guinea pigsin vivo.
Sequence	DSFVALM(Modifications: Ala-5 = β-Ala, Met-7 = C-terminal amide)

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Peptidomimetics
    - Subclass Hybrid peptides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Peptidomimetics
Subclass	Hybrid peptides
Intermediate Tree Nodes	Not available
Direct Parent	Hybrid peptides
Alternative Parents	Dipeptides Phenylalanine and derivatives Aspartic acid and derivatives Methionine and derivatives Leucine and derivatives Valine and derivatives N-acyl-alpha amino acids and derivatives Alpha amino acid amides Serine and derivatives Beta amino acids and derivatives Amphetamines and derivatives N-acyl amines Secondary carboxylic acid amides Primary carboxylic acid amides Amino acids Sulfenyl compounds Monocarboxylic acids and derivatives Carboxylic acids Dialkylthioethers Carbonyl compounds Primary alcohols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Hybrid peptide - Alpha-dipeptide - Phenylalanine or derivatives - Methionine or derivatives - Aspartic acid or derivatives - Leucine or derivatives - N-acyl-alpha amino acid or derivatives - Valine or derivatives - Alpha-amino acid amide - Serine or derivatives - Beta amino acid or derivatives - Alpha-amino acid or derivatives - N-substituted-alpha-amino acid - Amphetamine or derivatives - Fatty amide - Fatty acyl - N-acyl-amine - Benzenoid - Monocyclic benzene moiety - Amino acid or derivatives - Amino acid - Carboxamide group - Secondary carboxylic acid amide - Primary carboxylic acid amide - Carboxylic acid - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Thioether - Dialkylthioether - Sulfenyl compound - Alcohol - Primary aliphatic amine - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Carbonyl group - Primary alcohol - Primary amine - Hydrocarbon derivative - Organic oxide - Amine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Storage and Shipping

Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
CAS	122063-01-8

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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4 results found

Lot Number	Certificate Type	Date	Item
J2119122	Certificate of Analysis	Aug 09, 2024	B286633
J2119124	Certificate of Analysis	Aug 09, 2024	B286633
J2119197	Certificate of Analysis	Aug 09, 2024	B286633
J2119223	Certificate of Analysis	Aug 09, 2024	B286633

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