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β-Propiolactone - >98.0%(GC), high purity , CAS No.57-57-8

6 Citations

COA

Grade & Purity:

≥98%(GC)

Cas Number: 57-57-8
Molecular Weight: 72.06
EC Number: 200-340-1
MDL number: MFCD00005169
PubChem CID: 2365

In stock

Item Number

P639527

Grouped product items
SKU	Size	Availability	Price
P639527-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$124.90
P639527-5ml	5ml	2	$340.90
P639527-25ml	25ml	2	$1,193.90
P639527-100ml	100ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,044.90

View related series

Virus (1811)

Basic Description

Synonyms	beta-propiolactone \| 2-Oxetanone \| Propiolactone \| 57-57-8 \| Oxetan-2-one \| Betaprone \| Propanolide \| 3-Propanolide \| 1,3-Propiolactone \| 3-Propiolactone \| beta-Propionolactone \| beta-Propiolakton \| Propiolactona \| Propiolactonum \| Propiolattone \| Hydracrylic acid beta-lactone \| .beta.-
Specifications & Purity	≥98%(GC)
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Lactones
    - Subclass Beta propiolactones

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Lactones
Subclass	Beta propiolactones
Intermediate Tree Nodes	Not available
Direct Parent	Beta propiolactones
Alternative Parents	Oxetanes Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Beta_propiolactone - Oxetane - Carboxylic acid ester - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as beta propiolactones. These are organic compounds containing a four-member lactone (a cyclic ester).
External Descriptors	propan-3-olide
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	oxetan-2-one
INCHI	InChI=1S/C3H4O2/c4-3-1-2-5-3/h1-2H2
InChIKey	VEZXCJBBBCKRPI-UHFFFAOYSA-N
Smiles	C1COC1=O
Isomeric SMILES	C1COC1=O
WGK Germany	3
RTECS	RQ7350000
PubChem CID	2365
UN Number	2810
Packing Group	I
Molecular Weight	72.06

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number	Certificate Type	Date	Item
C2404166	Certificate of Analysis	Mar 16, 2024	P639527
E2513015	Certificate of Analysis	Mar 16, 2024	P639527
E2513017	Certificate of Analysis	Mar 16, 2024	P639527
A2513312	Certificate of Analysis	Mar 16, 2024	P639527
A2513313	Certificate of Analysis	Mar 16, 2024	P639527
C2404164	Certificate of Analysis	Mar 15, 2024	P639527
C2404165	Certificate of Analysis	Mar 15, 2024	P639527
C2421002	Certificate of Analysis	Mar 15, 2024	P639527

Chemical and Physical Properties

Solubility	Soluble in water and miscible in ethanol.
Sensitivity	Heat sensitive;Moisture sensitive
Refractive Index	1.4131
Flash Point(°F)	158 °F
Flash Point(°C)	70℃
Boil Point(°C)	162.3°C
Melt Point(°C)	-33.4°C
Molecular Weight	72.060 g/mol
XLogP3	-0.200
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	72.0211 Da
Monoisotopic Mass	72.0211 Da
Topological Polar Surface Area	26.300 Å²
Heavy Atom Count	5
Formal Charge	0
Complexity	57.900
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yongheng Yin, Hui Xu, Chenyang Zhang, Weiyuan Hao, Qiying Xia, Shanmin Gao. (2023) Fabrication of polyamide/zwitterion functionalized mesoporous silica nanofiltration membrane with highly enhanced antifouling performance. Journal of the Taiwan Institute of Chemical Engineers, 147 (104892).
2. Ting Wang, Jing Deng, Ruijin Ran, Wenqiang Shi, Yunxia Gao, Xiang Ren, Jun Cao, Ming Zhang. (2022) In-situ forming PEG-engineering hydrogels with anti-fouling characteristics as an artificial vitreous body. CHEMICAL ENGINEERING JOURNAL, 449 (137486).
3. Jin Ma, Ke Kang, Yujia Zhang, Qiangying Yi, Zhongwei Gu. (2018) Detachable Polyzwitterion-Coated Ternary Nanoparticles Based on Peptide Dendritic Carbon Dots for Efficient Drug Delivery in Cancer Therapy. ACS Applied Materials & Interfaces, 10 (50): (43923–43935).
4. Liping Zhu, Xiaodong Li, Changjian Song, Xiaohui Liu, Ying-Chiao Wang, Wenjun Zhang, Junfeng Fang. (2017) Cathode modification in planar hetero-junction perovskite solar cells through a small-molecule zwitterionic carboxylate. ORGANIC ELECTRONICS, 48 (204).
5. Jin Ma, Ke Kang, Qiangying Yi, Zhirong Zhang, Zhongwei Gu. (2016) Multiple pH responsive zwitterionic micelles for stealth delivery of anticancer drugs. RSC Advances, 6 (69): (64778-64790).
6. Sixu Liu, Jingqi Li, Qingtian Cheng, Kangyi Duan, Zhan Wang, Shuang Yan, Shuaishuai Tian, Hairui Wang, Shaobin Wu, Xinkui Lei, Yu Yang, Ningning Ma. (2024) A Single-Step Method for Harvesting Influenza Viral Particles from MDCK Cell Culture Supernatant with High Yield and Effective Impurity Removal. Viruses-Basel, 16 (5): (768).

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