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β-Elemonic acid - 98%, high purity , CAS No.28282-25-9

COA

Grade & Purity:

≥98%

Cas Number: 28282-25-9
Molecular Weight: 454.68
PubChem CID: 15559100
PubChem SID: 504767898

In stock

Item Number

E334593

Grouped product items
SKU	Size	Availability	Price
E334593-5mg	5mg	3	$245.90
E334593-25mg	25mg	2	$1,107.90
E334593-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,992.90
E334593-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,586.90
E334593-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$8,070.90

View related series

Amino Acid/Protein Metabolism (1836) Apoptosis (4276) COX (258) Glucose Metabolism (1943) Immunology/Inflammation (1929) Metabolic Enzyme/Protease (4860) Metabolite (5307) Prolyl Endopeptidase (PREP) (9)

Basic Description

Synonyms	BETA-ELEMONICACID \| BDBM50039667 \| (2S)-6-methyl-2-[(5R,10S,13S,14S,17S)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-5-enoic acid \| b-Elemonic acid \| AKOS016036180 \| Elemonic acid \| 3-Oxotirucalleno
Specifications & Purity	≥98%
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Application: β-Elemonic acid is a triterpene isolated from Boswellia that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 µM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 µM) in vitro.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Prenol lipids
    - Subclass Triterpenoids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Prenol lipids
Subclass	Triterpenoids
Intermediate Tree Nodes	Not available
Direct Parent	Triterpenoids
Alternative Parents	Bile acids, alcohols and derivatives Steroid acids 3-oxo-5-alpha-steroids Medium-chain fatty acids Unsaturated fatty acids Cyclic ketones Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic homopolycyclic compounds
Substituents	Triterpenoid - Bile acid, alcohol, or derivatives - Steroid acid - 3-oxosteroid - Oxosteroid - 3-oxo-5-alpha-steroid - Steroid - Medium-chain fatty acid - Fatty acyl - Fatty acid - Unsaturated fatty acid - Ketone - Cyclic ketone - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organooxygen compound - Organic oxygen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aliphatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504767898
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504767898
IUPAC Name	(2S)-6-methyl-2-[(5R,10S,13S,14S,17S)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-5-enoic acid
INCHI	InChI=1S/C30H46O3/c1-19(2)9-8-10-20(26(32)33)21-13-17-30(7)23-11-12-24-27(3,4)25(31)15-16-28(24,5)22(23)14-18-29(21,30)6/h9,20-21,24H,8,10-18H2,1-7H3,(H,32,33)/t20-,21-,24-,28+,29-,30+/m0/s1
InChIKey	XLPAINGDLCDYQV-SDTWUMECSA-N
Smiles	CC(=CCCC(C1CCC2(C1(CCC3=C2CCC4C3(CCC(=O)C4(C)C)C)C)C)C(=O)O)C
Isomeric SMILES	CC(=CCC[C@@H]([C@@H]1CC[C@]2([C@]1(CCC3=C2CC[C@@H]4[C@@]3(CCC(=O)C4(C)C)C)C)C)C(=O)O)C
Molecular Weight	454.68
Reaxy-Rn	42764299
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=42764299&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
C23081485	Certificate of Analysis	Jan 03, 2023	E334593
C23081489	Certificate of Analysis	Jan 03, 2023	E334593
C23081490	Certificate of Analysis	Jan 03, 2023	E334593
C23081487	Certificate of Analysis	Jan 03, 2023	E334593
C23081491	Certificate of Analysis	Jan 03, 2023	E334593
F2516054	Certificate of Analysis	Jan 03, 2023	E334593

Chemical and Physical Properties

Solubility	30 mg/ml in DMF；5 mg/ml in DMSO & Ethanol;
Molecular Weight	454.700 g/mol
XLogP3	7.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	454.345 Da
Monoisotopic Mass	454.345 Da
Topological Polar Surface Area	54.400 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	904.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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