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AX-024 HCl - 99%, high purity , CAS No.1704801-24-0

COA

Grade & Purity:

≥99%

Cas Number: 1704801-24-0
Molecular Weight: 375.86
PubChem CID: 129909862
PubChem SID: 504773066

In stock

Item Number

A413602

Grouped product items
SKU	Size	Availability	Price
A413602-2mg	2mg	3	$72.90
A413602-5mg	5mg	3	$151.90
A413602-10mg	10mg	3	$238.90
A413602-25mg	25mg	3	$554.90
A413602-50mg	50mg	2	$946.90
A413602-100mg	100mg	2	$1,523.90

CD markers Inhibitors

View related series

Apoptosis (4276) Extrinsic Pathway (436) IFNAR (25) Immunology/Inflammation (1929) Interleukin Related (129) TNF Receptor (121)

Basic Description

Synonyms	AX-024 hydrochloride \| 1-[[4-(4-fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]-,hydrochloride (1:1)
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	AX-024 HCl blocks the interaction of the CD3ε PRS with SH3.1(Nck). AX-024 HCl also inhibits IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information AX-024 HCl AX-024 HCl blocks the interaction of the CD3ε PRS with SH3.1(Nck). AX-024 HCl also inhibits IL-6 , TNF-α , IFN-γ , IL-10 and IL-17A .

Product Properties

ALogP	4.579
hba_count	2
Rotatable Bond	4

Names and Identifiers

Pubchem Sid	504773066
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504773066
IUPAC Name	1-[[4-(4-fluorophenyl)-6-methoxy-2H-chromen-3-yl]methyl]pyrrolidine;hydrochloride
INCHI	InChI=1S/C21H22FNO2.ClH/c1-24-18-8-9-20-19(12-18)21(15-4-6-17(22)7-5-15)16(14-25-20)13-23-10-2-3-11-23;/h4-9,12H,2-3,10-11,13-14H2,1H3;1H
InChIKey	DGBCIMPGYRVTPD-UHFFFAOYSA-N
Smiles	COC1=CC2=C(C=C1)OCC(=C2C3=CC=C(C=C3)F)CN4CCCC4.Cl
Alternate CAS	1370544-73-2
Molecular Weight	375.86
Reaxy-Rn	30387316
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30387316&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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6 results found

Lot Number	Certificate Type	Date	Item
F2230051	Certificate of Analysis	Apr 03, 2025	A413602
F2230052	Certificate of Analysis	Apr 03, 2025	A413602
F2230054	Certificate of Analysis	Apr 03, 2025	A413602
F2230062	Certificate of Analysis	Apr 03, 2025	A413602
F2230046	Certificate of Analysis	Apr 03, 2025	A413602
F2230045	Certificate of Analysis	Apr 03, 2025	A413602

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 75 mg/mL (199.54 mM); Ethanol: 18 mg/mL (47.89 mM); Water: 4 mg/mL (10.64 mM);
DMSO(mg / mL) Max Solubility	75
DMSO(mM) Max Solubility	199.542382802107
Water(mg / mL) Max Solubility	4
Water(mM) Max Solubility	10.6422604161124
Molecular Weight	375.900 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	375.14 Da
Monoisotopic Mass	375.14 Da
Topological Polar Surface Area	21.700 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	480.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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