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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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A413268-5mg
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5mg |
3
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$86.90
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|
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A413268-25mg
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25mg |
2
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$391.90
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|
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A413268-100mg
|
100mg |
2
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$815.90
|
|
GABA Receptor Activators
| Synonyms | 1-(4-Chlorophenyl)-1,5-dihydro-4-(4-morpholinyl)-2H-imidazol-2-one | ADD-233089 | imepitoinum | AC-36287 | Imepitoin | imepitoine | BCP08396 | HMS3886O19 | 2H-Imidazol-2-one, 1-(4-chlorophenyl)-1,5-dihydro-4-(4-morpholinyl)- | IMEPITOIN [EMA EPAR VETERINA |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | AWD 131-138 (Imepitoin, ELB-138) is a centrally acting anti-epileptic which crosses the blood brain barrier and is used for the treatment of canine idiopathic epilepsy. AWD 131-138 (Imepitoin) is an antiepileptic and antianxietic drug, AWD 131-138 can sti |
| Storage Temp | Protected from light,Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Information AWD 131-138 AWD 131-138 (Imepitoin, ELB-138) is a centrally acting anti-epileptic which crosses the blood brain barrier and is used for the treatment of canine idiopathic epilepsy. AWD 131-138 (Imepitoin) is an antiepileptic and antianxietic drug, AWD 131-138 can stimulate different recombinant isoforms of the rat GABA(A) receptor through the benzodiazepine binding site. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Halobenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Chlorobenzenes |
| Alternative Parents | Morpholines Aryl chlorides Imidazolines Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Dialkyl ethers Carboximidamides Carboxamidines Azacyclic compounds Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Amines |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Chlorobenzene - Aryl chloride - Aryl halide - Morpholine - Oxazinane - 3-imidazoline - Amidine - Carboxylic acid amidine - Dialkyl ether - Ether - Oxacycle - Azacycle - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Hydrocarbon derivative - Organic oxygen compound - Organohalogen compound - Organochloride - Organonitrogen compound - Organooxygen compound - Carbonyl group - Amine - Organic oxide - Organic nitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as chlorobenzenes. These are compounds containing one or more chlorine atoms attached to a benzene moiety. |
| External Descriptors | Not available |
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| ALogP | 1.44 |
|---|---|
| hba_count | 3 |
| Rotatable Bond | 2 |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| Pubchem Sid | 504762407 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504762407 |
| IUPAC Name | 3-(4-chlorophenyl)-5-morpholin-4-yl-4H-imidazol-2-one |
| INCHI | InChI=1S/C13H14ClN3O2/c14-10-1-3-11(4-2-10)17-9-12(15-13(17)18)16-5-7-19-8-6-16/h1-4H,5-9H2 |
| InChIKey | IQHYCZKIFIHTAI-UHFFFAOYSA-N |
| Smiles | C1COCCN1C2=NC(=O)N(C2)C3=CC=C(C=C3)Cl |
| Isomeric SMILES | C1COCCN1C2=NC(=O)N(C2)C3=CC=C(C=C3)Cl |
| Molecular Weight | 279.72 |
| Reaxy-Rn | 8917426 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8917426&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 09, 2025 | A413268 | |
| Certificate of Analysis | May 09, 2025 | A413268 | |
| Certificate of Analysis | May 09, 2025 | A413268 |
| Solubility | Solubility (25°C) In vitro DMSO: 30 mg/mL (107.25 mM); Ethanol: 2 mg/mL (7.15 mM); Water: Insoluble; |
|---|---|
| Sensitivity | light sensitive |
| DMSO(mg / mL) Max Solubility | 30 |
| DMSO(mM) Max Solubility | 107.250107250107 |
| Water(mg / mL) Max Solubility | <1 |
| Molecular Weight | 279.720 g/mol |
| XLogP3 | 1.200 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 279.077 Da |
| Monoisotopic Mass | 279.077 Da |
| Topological Polar Surface Area | 45.100 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 374.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |