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Avicularin - 98%, high purity , CAS No.572-30-5

6 Citations COA COA
In stock
Item Number
A664202
Grouped product items
SKU Size
Availability
 Price Qty
A664202-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$92.90
A664202-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$154.90
A664202-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$281.90
A664202-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$416.90
A664202-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$615.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet
View related series
Apoptosis (4276) Cell Cycle (2830) Lipid metabolism (1912) Membrane Transporter (607)

Basic Description

Synonyms Fenicularin | Quercetin 3-α-L-arabinofuranoside | 3,3 ′, 4 ′, 5,7-pentahydroxyflavone 3-O - α - L furan arabinoside
Specifications & Purity Moligand™, ≥98%
Storage Temp Store at 2-8°C,Protected from light
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Product Description

Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Flavonoids
Subclass Flavonoid glycosides
Intermediate Tree Nodes Flavonoid O-glycosides
Direct Parent Flavonoid-3-O-glycosides
Alternative Parents 3'-hydroxyflavonoids  4'-hydroxyflavonoids  5-hydroxyflavonoids  7-hydroxyflavonoids  Flavones  Chromones  O-glycosyl compounds  Pentoses  Catechols  1-hydroxy-2-unsubstituted benzenoids  Pyranones and derivatives  1-hydroxy-4-unsubstituted benzenoids  Benzene and substituted derivatives  Heteroaromatic compounds  Tetrahydrofurans  Vinylogous acids  Secondary alcohols  Oxacyclic compounds  Acetals  Hydrocarbon derivatives  Primary alcohols  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Flavonoid-3-o-glycoside - 3'-hydroxyflavonoid - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Flavone - Hydroxyflavonoid - Chromone - Glycosyl compound - O-glycosyl compound - Benzopyran - 1-benzopyran - Pentose monosaccharide - Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Pyran - Monocyclic benzene moiety - Benzenoid - Monosaccharide - Heteroaromatic compound - Vinylogous acid - Tetrahydrofuran - Secondary alcohol - Oxacycle - Acetal - Organoheterocyclic compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Organic oxygen compound - Organic oxide - Primary alcohol - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position.
External Descriptors Flavones and Flavonols

Associated Targets(Human)

XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FASN Tchem Fatty acid synthase (3390 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A549 (127892 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Monocyte (474 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HeLa (62764 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Dolichospermum flos-aquae (8 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida parapsilosis (8521 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Dengue virus (413 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
INCHI InChI=1S/C20H18O11/c21-6-13-15(26)17(28)20(30-13)31-19-16(27)14-11(25)4-8(22)5-12(14)29-18(19)7-1-2-9(23)10(24)3-7/h1-5,13,15,17,20-26,28H,6H2/t13-,15-,17+,20-/m0/s1
InChIKey BDCDNTVZSILEOY-UXYNSRGZSA-N
Smiles C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(O4)CO)O)O)O)O
Isomeric SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H](O4)CO)O)O)O)O
PubChem CID 5490064
Molecular Weight 434.35

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number Certificate Type Date Item
C2527372 Certificate of Analysis Mar 24, 2025 A664202
C2527373 Certificate of Analysis Mar 24, 2025 A664202
C2527378 Certificate of Analysis Mar 24, 2025 A664202
C2527354 Certificate of Analysis Mar 24, 2025 A664202
C2527367 Certificate of Analysis Mar 24, 2025 A664202

Chemical and Physical Properties

Molecular Weight 434.300 g/mol
XLogP3 1.000
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 4
Exact Mass 434.085 Da
Monoisotopic Mass 434.085 Da
Topological Polar Surface Area 186.000 Ų
Heavy Atom Count 31
Formal Charge 0
Complexity 711.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Qi Dong, Na Hu, Huilan Yue, Honglun Wang, Yue Wei.  (2022)  Rapid screening of α-glucosidase inhibitors in Hypericum perforatum L. using bio-affinity chromatography coupled with UPLC/MS.  BIOMEDICAL CHROMATOGRAPHY,  37  (2): (e5536). 
2. You Luo, Haiqing Liu, Shanzhong Yang, Jiarui Zeng, Zhenqiang Wu.  (2019)  Sodium Alginate-Based Green Packaging Films Functionalized by Guava Leaf Extracts and Their Bioactivities.  Materials,  12  (18): (2923). 
3. Zhimin Wang, Fang Li, Yuan Quan, Junye Shen.  (2019)  Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities.  Molecular Medicine Reports,  19  (6): (5417-5423). 
4. Zhongfei Shen, Yun Xu, Xiaohong Jiang, Zhijian Wang, Yanjun Guo, Weiwei Pan, Jie Hou.  (2019)  Avicularin Relieves Depressive-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice.  MEDICAL SCIENCE MONITOR,  25  ( 2777–2784). 
5. Wei-min Zhang, Rui-fang Li, Ming Sun, Da-ming Hu, Jian-fei Qiu, Yun-hao Yan.  (2014)  UPLC–MS/MS method for determination of avicularin in rat plasma and its application to a pharmacokinetic study.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  965  (107). 
6. Xijin Yang, Ying Li, Qiju Shao, Zhirong Li, Zeli Chun, Yan Wang, Yaping Zhou, Rongxiang Chen.  (2025)  Screening, fingerprinting, and identification of phenolic antioxidants in Persicaria chinensis (L.) H. Gross by liquid chromatography – electrochemical detection and liquid chromatography – tandem mass spectrometry.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  1250  (124387). 

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