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Avibactam sodium hydrate , CAS No.A659058

  • Molecular Weight:  305.24
In stock
Item Number
A659058
Grouped product items
SKU Size
Availability
Price Qty
A659058-2mg
2mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$50.90
A659058-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$72.90
A659058-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$96.90
A659058-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$156.90
A659058-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$228.90
A659058-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$312.90

Basic Description

Storage Temp Store at 2-8°C,Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively.

Appearance:Solid

IC50& Target:IC 50 : 5 nM (CTX-M-15), 8 nM (TEM-1)

In Vitro:Avibactam is a molecule with little antibacterial activity, that inhibits class A and C β-lactamases, but not metallo types and Acinetobacter OXA carbapenemases. Ceftazidime (HY-B0593)-Avibactam (0-256 mg/L) inhibits 16 bla KPC-2 positive and 1 of bl

In Vivo:Ceftazidime-Avibactam (0.375 mg/g; s.c.; q8h for 10 days) has a significant effect on the bacteria and led to a certain therapeutic efficacy in K. pneumoniae strain Y8 infected mouse model. Avibactam (64mg/kg; s.c.; once) shows mean estimated half-l

Biological Activity:Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively.

Names and Identifiers

Smiles O=S(ON1[C@]2([H])CC[C@@H](C(N)=O)[N@@](C2)C1=O)(O[Na])=O.O
Molecular Weight 305.24

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility H2O : ≥ 200 mg/mL (655.22 mM)

Solution Calculators

Reviews

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