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Basic Description
| Product Name | Astressin 2B, CAS No.681260-70-8 |
|---|---|
| Synonyms | astressin-2B | Cyclo(31-34)(Phe(11),His(12),CMeLeu(13,39),Nle(17),Glu(31),Lys(34)) Ac-sauvagine (8-40) | cyclo(31-34)(Phe11,His12,CMeLeu13,39,Nle17,Glu31,Lys34) Ac-sauvagine(8-40) | ASTRESSIN 2B |
| Biochemical and Physiological Mechanisms | Potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist (IC50values are 1.3 and > 500 nM for CRF2and CRF1respectively). Antagonizes CRF2-mediated inhibition of gastric emptying. |
| Sequence | DLSFHLLRKXIEIEKQEKEKQQAENNKLLLDLI(Modifications: Asp-1 = N-terminal Ac, Phe-4 = D-Phe, Leu-6 = α-methyl-Leu, X = Nle, Glu-24 = γ-Glu, Lys-27 = ε-Lys, Leu-32 = α-methyl-Leu, Lactam Bridge = Glu-24 - Lys-27) |
Storage and Shipping
| Storage Temp | Store at -20°C |
|---|---|
| Shipped In | Ice chest + Ice pads |
| CAS | 681260-70-8 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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