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| SKU | Size | Availability |
Price | Qty |
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A111276-10mg
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10mg |
3
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$29.90
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A111276-20mg
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20mg |
2
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$49.90
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A111276-50mg
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50mg |
2
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$99.90
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A111276-250mg
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250mg |
2
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$299.90
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A111276-1g
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1g |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$699.90
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Triterpene glycoside. Stimulates collagen biosynthesis and glycosaminoglycan synthesis.
| Synonyms | (-)-SENECIONINE | NSC-36002 | (2alpha,3beta,4alpha)-2,3,23-TRIHYDROXYURS-12-EN-28-OIC ACID O-6-DEOXY-alpha-L-MANNOPYRANOSYL-(1->4)-O-beta-D-GLUCOPYRANOSYL-(1->6)-O-beta-D-GLUCOPYRANOSYL ESTER | Madecassol | Prost-13-en-1-oic acid, 11,15-dihydroxy-6,9-diox |
|---|---|
| Specifications & Purity | analytical standard, Moligand™, ≥98% |
| Biochemical and Physiological Mechanisms | Triterpene glycoside. Stimulates collagen biosynthesis and glycosaminoglycan synthesis. Displays wound-healing activity. Antiaging and anti-infective agent. Active in vivo and in vitro . |
| Storage Temp | Store at 2-8°C,Argon charged |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | analytical standard, Moligand™ |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Prenol lipids |
| Subclass | Terpene glycosides |
| Intermediate Tree Nodes | Triterpene glycosides |
| Direct Parent | Triterpene saponins |
| Alternative Parents | Triterpenoids Oligosaccharides 12-beta-hydroxysteroids O-glycosyl compounds Oxanes Secondary alcohols Carboxylic acid esters Cyclic alcohols and derivatives Monocarboxylic acids and derivatives Acetals Polyols Oxacyclic compounds Primary alcohols Hydrocarbon derivatives Carbonyl compounds Organic oxides |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Triterpene saponin - Triterpenoid - Oligosaccharide - 12-hydroxysteroid - Hydroxysteroid - 12-beta-hydroxysteroid - Steroid - Glycosyl compound - O-glycosyl compound - Oxane - Cyclic alcohol - Secondary alcohol - Carboxylic acid ester - Polyol - Organoheterocyclic compound - Oxacycle - Monocarboxylic acid or derivatives - Acetal - Carboxylic acid derivative - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Carbonyl group - Alcohol - Primary alcohol - Aliphatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as triterpene saponins. These are glycosylated derivatives of triterpene sapogenins. The sapogenin moiety backbone is usually based on the oleanane, ursane, taraxastane, bauerane, lanostane, lupeol, lupane, dammarane, cycloartane, friedelane, hopane, 9b,19-cyclo-lanostane, cycloartane, or cycloartanol skeleton. |
| External Descriptors | triterpenoid saponin |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| IUPAC Name | [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate |
|---|---|
| INCHI | InChI=1S/C48H78O19/c1-20-10-13-48(15-14-46(6)23(29(48)21(20)2)8-9-28-44(4)16-24(51)39(60)45(5,19-50)27(44)11-12-47(28,46)7)43(61)67-42-36(58)33(55)31(53)26(65-42)18-62-40-37(59)34(56)38(25(17-49)64-40)66-41-35(57)32(54)30(52)22(3)63-41/h8,20-22,24-42,49-60H,9-19H2,1-7H3/t20-,21+,22+,24-,25-,26-,27-,28-,29+,30+,31-,32-,33+,34-,35-,36-,37-,38-,39+,40-,41+,42+,44+,45+,46-,47-,48+/m1/s1 |
| InChIKey | WYQVAPGDARQUBT-FGWHUCSPSA-N |
| Smiles | CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O |
| Isomeric SMILES | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O)O)O)O |
| WGK Germany | 3 |
| Molecular Weight | 959.12 |
| Reaxy-Rn | 25443182 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25443182&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 16, 2025 | A111276 | |
| Certificate of Analysis | Apr 10, 2025 | A111276 | |
| Certificate of Analysis | Apr 10, 2025 | A111276 | |
| Certificate of Analysis | Apr 10, 2025 | A111276 | |
| Certificate of Analysis | Apr 10, 2025 | A111276 | |
| Certificate of Analysis | Aug 03, 2024 | A111276 | |
| Certificate of Analysis | Aug 03, 2024 | A111276 | |
| Certificate of Analysis | Aug 03, 2024 | A111276 | |
| Certificate of Analysis | Jul 19, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Apr 10, 2024 | A111276 | |
| Certificate of Analysis | Jul 31, 2023 | A111276 | |
| Certificate of Analysis | Jul 31, 2023 | A111276 | |
| Certificate of Analysis | Jun 09, 2023 | A111276 | |
| Certificate of Analysis | Aug 08, 2022 | A111276 | |
| Certificate of Analysis | Jul 11, 2022 | A111276 |
| Sensitivity | Moisture sensitive;Heat sensitive |
|---|---|
| Melt Point(°C) | 230-233°C |
| Molecular Weight | 959.100 g/mol |
| XLogP3 | 0.100 |
| Hydrogen Bond Donor Count | 12 |
| Hydrogen Bond Acceptor Count | 19 |
| Rotatable Bond Count | 10 |
| Exact Mass | 958.514 Da |
| Monoisotopic Mass | 958.514 Da |
| Topological Polar Surface Area | 315.000 Ų |
| Heavy Atom Count | 67 |
| Formal Charge | 0 |
| Complexity | 1820.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 27 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 1. Wang Pei, Wang Yun, Yi Yang, Gong Yan, Ji Haoran, Gan Yuci, Xie Fei, Fan Jinchen, Wang Xiansong. (2022) MXenes-integrated microneedle combined with asiaticoside to penetrate the cuticle for treatment of diabetic foot ulcer. JOURNAL OF NANOBIOTECHNOLOGY, 20 (1): (1-14). |
| 2. Keyan Wu, Guanghuai Yao, Xiaolei Shi, Huan Zhang, Qingtian Zhu, Xinnong Liu, Guotao Lu, Lianghao Hu, Weijuan Gong, Qi Yang, Yanbing Ding. (2021) Asiaticoside ameliorates acinar cell necrosis in acute pancreatitis via toll-like receptor 4 pathway. MOLECULAR IMMUNOLOGY, 130 (122). |