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Aristolochic acid C - ≥95%, high purity , CAS No.4849-90-5

COA

Grade & Purity:

≥95%

Cas Number: 4849-90-5
Molecular Weight: 327.25
PubChem CID: 165274
PubChem SID: 504757566

In stock

Item Number

A275388

Grouped product items
SKU	Size	Availability	Price
A275388-1mg	1mg	3	$225.90
A275388-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$678.90
A275388-10mg	10mg	2	$1,222.90
A275388-25mg	25mg	1	$2,749.90
A275388-100mg	100mg	2	$9,899.90

Mycotoxin. Aristolochic acid derivative.

View related series

Lipid metabolism (1912) Metabolic Enzyme/Protease (4860) Phospholipase (108)

Basic Description

Synonyms	10-hydroxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid \| DTXSID00197540 \| ARISTOLOCHICACIDC \| Aristolochiac acid C \| CHEBI:194151 \| Phenanthro[3,4-d]-1,3-dioxole-5-carboxylicacid, 10-hydroxy-6-nitro- \| 10-hydroxy-6-nitrophenanthro[3,4-d][1,3]
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Mycotoxin. Aristolochic acid derivative ( Asc 2618 ). Possible mutagenic and nephrotoxic agent as a constituent aristolochic acid.
Storage Temp	Store at -20°C,Argon charged,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Phenanthrenes and derivatives
    - Subclass Aristolochic acids and derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Phenanthrenes and derivatives
Subclass	Aristolochic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Aristolochic acids and derivatives
Alternative Parents	Phenanthrols Nitronaphthalenes Naphthalenecarboxylic acids Naphthols and derivatives Benzodioxoles Nitroaromatic compounds 1-hydroxy-2-unsubstituted benzenoids Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Acetals Organic oxoazanium compounds Monocarboxylic acids and derivatives Carboxylic acids Hydrocarbon derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Aristolochic acid or derivatives - Phenanthrol - 1-naphthalenecarboxylic acid - 1-naphthalenecarboxylic acid or derivatives - 1-nitronaphthalene - 2-nitronaphthalene - 2-naphthol - Naphthalene - Benzodioxole - Nitroaromatic compound - 1-hydroxy-2-unsubstituted benzenoid - C-nitro compound - Organic nitro compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Oxacycle - Acetal - Organoheterocyclic compound - Organic 1,3-dipolar compound - Organic oxoazanium - Organic oxygen compound - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as aristolochic acids and derivatives. These are organic heterocyclic compounds with a structure characterized by a nitrophenanthro[3,4-d][1,3]dioxole ring system substituted at position 5, 6, and 8 by a carboxyl group (or a derivative thereof), a nitro group, and a methoxy group, respectively.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

Discover Target: CDK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504757566
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504757566
IUPAC Name	10-hydroxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
INCHI	InChI=1S/C16H9NO7/c18-8-2-1-7-3-11(17(21)22)13-10(16(19)20)5-12-15(24-6-23-12)14(13)9(7)4-8/h1-5,18H,6H2,(H,19,20)
InChIKey	NBFGYDJKTHENDP-UHFFFAOYSA-N
Smiles	C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O
Isomeric SMILES	C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O
Molecular Weight	327.25
Reaxy-Rn	343733
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=343733&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
F2403151	Certificate of Analysis	May 15, 2024	A275388
B2215092	Certificate of Analysis	Aug 11, 2023	A275388
B2215135	Certificate of Analysis	Aug 11, 2023	A275388
B2215122	Certificate of Analysis	Aug 11, 2023	A275388
B2215095	Certificate of Analysis	Aug 11, 2023	A275388
B2215127	Certificate of Analysis	Aug 11, 2023	A275388

Chemical and Physical Properties

Solubility	DMSO (Slightly), Methanol (Slightly, Heated)
Sensitivity	Light sensitive
Molecular Weight	327.240 g/mol
XLogP3	3.200
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	1
Exact Mass	327.038 Da
Monoisotopic Mass	327.038 Da
Topological Polar Surface Area	122.000 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	535.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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