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Apramycin sulfate salt - 10mM in Water, high purity , CAS No.65710-07-8

    Grade & Purity:
  • 10mM in Water
In stock
Item Number
A425315
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A425315-1ml
1ml
Available within 8-12 weeks(?)
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$38.90

Aminoglycoside antibiotic agent. Potent protein synthesis inhibitor.

Basic Description

Synonyms Apramycin sulfate | 65710-07-8 | Apramycin sulphate | Apramycin (sulfate) | UNII-8UYL6NAZ3Q | 8UYL6NAZ3Q | AI3-29795 | EINECS 265-890-7 | 410097-64-2 | Apramycin, sulfate (2:5) | (+)-APRAMYCIN SULFATE | APRAMYCIN SULFATE (MART.) | APRAMYCIN SULFATE [MART.] | (2R,3R,4S,5S,6S)-2-[[(
Specifications & Purity 10mM in Water
Biochemical and Physiological Mechanisms Aminoglycoside antibiotic agent. Potent protein synthesis inhibitor. Inhibits translocation. Shows bactericidal effects in vivo. Orally active.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic oxygen compounds
Class Organooxygen compounds
Subclass Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes Aminosaccharides - Aminoglycosides
Direct Parent Aminocyclitol glycosides
Alternative Parents Hexoses  Aminocyclitols and derivatives  Cyclohexanols  Cyclohexylamines  Oxanes  Organic sulfuric acids  1,3-aminoalcohols  1,2-aminoalcohols  Oxacyclic compounds  Acetals  Dialkylamines  Hydrocarbon derivatives  Monoalkylamines  Organic oxides  Organopnictogen compounds  Primary alcohols  
Molecular Framework Aliphatic heteropolycyclic compounds
Substituents Amino cyclitol glycoside - Hexose monosaccharide - Aminocyclitol or derivatives - Cyclohexanol - Cyclohexylamine - Sulfuric acid - Cyclitol or derivatives - Monosaccharide - Oxane - Organic sulfuric acid or derivatives - 1,3-aminoalcohol - Cyclic alcohol - Secondary alcohol - 1,2-aminoalcohol - Secondary amine - Acetal - Organoheterocyclic compound - Oxacycle - Secondary aliphatic amine - Primary alcohol - Organic oxide - Hydrocarbon derivative - Primary aliphatic amine - Organopnictogen compound - Organic nitrogen compound - Amine - Alcohol - Primary amine - Organonitrogen compound - Aliphatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as aminocyclitol glycosides. These are organic compounds containing an amicocyclitol moiety glycosidically linked to a carbohydrate moiety. There are two major classes of aminoglycosides containing a 2-streptamine core. They are called 4,5- and 4,6-disubstituted 2-deoxystreptamines.
External Descriptors Not available

Names and Identifiers

IUPAC Name (2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol;sulfuric acid
INCHI InChI=1S/C21H41N5O11.H2O4S/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31;1-5(2,3)4/h5-21,26-32H,2-4,22-25H2,1H3;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11+,12+,13+,14-,15-,16-,17-,18+,19+,20-,21-;/m1./s1
InChIKey WGLYHYWDYPSNPF-RQFIXDHTSA-N
Smiles CNC1C(C2C(CC(C(O2)OC3C(CC(C(C3O)O)N)N)N)OC1OC4C(C(C(C(O4)CO)N)O)O)O.OS(=O)(=O)O
Isomeric SMILES CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H]([C@H](O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O.OS(=O)(=O)O
WGK Germany 3
Alternate CAS 37321-09-8
PubChem CID 3081544
Molecular Weight 637.66

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Flash Point(°F) 230°F
Flash Point(°C) >110℃
Boil Point(°C) 823℃
Melt Point(°C) 168℃
Molecular Weight 637.700 g/mol
XLogP3
Hydrogen Bond Donor Count 13
Hydrogen Bond Acceptor Count 20
Rotatable Bond Count 6
Exact Mass 637.248 Da
Monoisotopic Mass 637.248 Da
Topological Polar Surface Area 367.000 Ų
Heavy Atom Count 42
Formal Charge 0
Complexity 841.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 17
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Citations of This Product

1. Lu Qi, Shanshan Liu, Zhen Yan, Min Qiao, Haonan Peng, Liping Ding.  (2024)  A cross-reactive fluorescent ensemble based on perylene derivative/surfactant assemblies for discrimination of multiple aminoglycoside antibiotics in aqueous solution.  JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,  446  (115128). 
2. Su Ping, Chen Xiaonan, He Zhangjing, Yang Yi.  (2017)  Preparation of polyclonal antibody and development of a biotin-streptavidin-based ELISA method for detecting kanamycin in milk and honey.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  33  (6): (876-881). 
3. Ye Tai, Luo Zheng, Che Yueyue, Yuan Min, Cao Hui, Hao Liling, Zhang Qian, Xie Yongxin, Zhang Kaisen, Xu Fei.  (2024)  An inverted tetrahedron-mediated DNA walker for sulfadimethoxine detection.  MICROCHIMICA ACTA,  191  (12): (1-10). 
4. Chuntong Liu, Haiyan Qi, Tao Jing, Jun Li, Ming Zhao, Lixin Qiu, Qiuying Li.  (2024)  Efficient electrochemical synthesis of green fluorescent carbon dots for curcumin detection in common foods.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  130  (106130). 
5. Tai Ye, Long Bai, Jinsong Yu, Weiyan Shi, Min Yuan, Juncheng Wang, Hui Cao, Liling Hao, Xiuxiu Wu, Fengqin Yin, Fei Xu.  (2025)  Fluorescent nanozyme for the dual-mode detection of tetracycline: Aggregation-induced luminescence and boosting peroxidase-like activity.  FOOD CONTROL,  171  (111109). 
6. Haohao Chen, Min Yuan, Fengqin Yin, Hui Cao, Xiuxiu Wu, Liling Hao, Weiyan Shi, Tai Ye, Fei Xu.  (2025)  Freezing-driven assembly of DNA walking machine facilitate G4 nanowires growth for electrochemical detection of kanamycin.  MICROCHEMICAL JOURNAL,  212  (113237). 
7. Tingting Wang, Huaizhi Yang, Qiushuang Sheng, Ying Ding, Jian Zhang, Feng Chen, Jianfeng Wang, Lei Song, Xuming Deng.  (2025)  Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.  PLoS Pathogens,  21  (1): (e1012787). 

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