Basic Description

Product Name	Amyloid β Protein Fragment 1-42,TFA - 95%, high purity , CAS No.107761-42-2(free base)
Product Description	Sequence: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala Biochemical mechanism: Amyloid protein β Protein segment 1-42 (A β 1-42) It has antioxidant and neuroprotective properties. Amyloid protein β Protein accumulation is associated with Alzheimer's disease (AD) and Down syndrome. A β 1-42 regulates cholesterol transport and acts as a transcription factor. It may also have anti-inflammatory and antimicrobial effects. Application: Amyloid protein is found in the brain of patients with Alzheimer's disease and Down syndrome β- The main segment of the protein. Amyloid protein β Protein fragments 1-42 have been used to: 1. A β Preparation of 1-42 oligomer 2. Western blot analysis 3. Immunomagnetic Reduction (IMR) Plasma A β 42 Detected interference test 4. Study the effect of resveratrol on A β 1-42 induced impairment of spatial learning, memory and synaptic plasticity 5. Study A β Role in epithelial cell culture
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Amyloid protein β Protein segment 1-42 (A β 1-42) It has antioxidant and neuroprotective properties. Amyloid protein β Protein accumulation is associated with Alzheimer's disease (AD) and Down syndrome. A β 1-42 regulates cholesterol transport and acts

Storage and Shipping

Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
CAS	107761-42-2(free base)

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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36 results found

Lot Number	Certificate Type	Date	Item
D2525478	Certificate of Analysis	Apr 08, 2025	A494432
D2525479	Certificate of Analysis	Apr 08, 2025	A494432
D2525476	Certificate of Analysis	Apr 08, 2025	A494432
D2525477	Certificate of Analysis	Apr 08, 2025	A494432
K2414237	Certificate of Analysis	Oct 29, 2024	A494432
K2414238	Certificate of Analysis	Oct 29, 2024	A494432
K2414239	Certificate of Analysis	Oct 29, 2024	A494432
K2414261	Certificate of Analysis	Oct 29, 2024	A494432
G2426068	Certificate of Analysis	Jul 10, 2024	A494432
G2426420	Certificate of Analysis	Jul 10, 2024	A494432
G2426424	Certificate of Analysis	Jul 10, 2024	A494432
G2426425	Certificate of Analysis	Jul 10, 2024	A494432
E2423164	Certificate of Analysis	May 14, 2024	A494432
E2423165	Certificate of Analysis	May 14, 2024	A494432
E2423166	Certificate of Analysis	May 14, 2024	A494432
E2423167	Certificate of Analysis	May 14, 2024	A494432
C2425145	Certificate of Analysis	Mar 16, 2024	A494432
C2429408	Certificate of Analysis	Mar 16, 2024	A494432
C2429410	Certificate of Analysis	Mar 16, 2024	A494432
C2429397	Certificate of Analysis	Mar 16, 2024	A494432
C2425146	Certificate of Analysis	Mar 16, 2024	A494432
C2429398	Certificate of Analysis	Mar 16, 2024	A494432
C2429409	Certificate of Analysis	Mar 16, 2024	A494432
C2429411	Certificate of Analysis	Mar 16, 2024	A494432
K2316030	Certificate of Analysis	Nov 04, 2023	A494432
K2316031	Certificate of Analysis	Nov 04, 2023	A494432
K2316032	Certificate of Analysis	Nov 04, 2023	A494432
K2316095	Certificate of Analysis	Nov 04, 2023	A494432
K2316096	Certificate of Analysis	Nov 04, 2023	A494432
K2316097	Certificate of Analysis	Nov 04, 2023	A494432
K2316098	Certificate of Analysis	Nov 04, 2023	A494432
K2316099	Certificate of Analysis	Nov 04, 2023	A494432
K2230884	Certificate of Analysis	Dec 06, 2022	A494432
K2230881	Certificate of Analysis	Dec 06, 2022	A494432
K2230885	Certificate of Analysis	Dec 06, 2022	A494432
K2230880	Certificate of Analysis	Dec 06, 2022	A494432

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Citations of This Product

How to Cite Aladdin Scientific Products?

1. Ling Zhu, Congyan Liu, Yang Wang, Xuanang Zhu, Lei Wu, Lvan Chen, Jing Zhou, Fan Wang. (2025) METTL3/IGF2BP2/IκBα axis participates in neuroinflammation in Alzheimer's disease by regulating M1/M2 polarization of microglia. NEUROCHEMISTRY INTERNATIONAL, (105964).
2. Qiang-Ming Li, Hui-Hui Han, Dan-Dan Zang, Xue-Qiang Zha, An Zhou, Feng-Yun Zhang, Jian-Ping Luo. (2024) Rapid Discovery of Aβ42 Fibril Disintegrators from Ganoderma lucidum via Ligand Fishing and Their Neuroprotective Effects on Alzheimer’s Disease. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 72 (8): (4127-4141).

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SKU	Size	Availability	Price
A494432-1mg	1mg	2	$279.90
A494432-2.5mg	2.5mg	1	$519.90
A494432-500μg	500μg	2	$199.90
A494432-5mg	5mg	1	$779.90
A494432-10mg	10mg	1	$999.90

Amyloid β Protein Fragment 1-42,TFA - 95%, high purity , CAS No.107761-42-2(free base)