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Amodiaquin dihydrochloride dihydrate - 97%, high purity , Ferriprotoporphyrin IX inhibitor, CAS No.6398-98-7, Ferriprotoporphyrin IX inhibitor

1 Citations COA COA
    Grade & Purity:
  • ≥97%
In stock
Item Number
A135245
Grouped product items
SKU Size
Availability
 Price Qty
A135245-5g
5g
2
$24.90
A135245-25g
25g
3
$80.90
A135245-100g
100g
2
$290.90
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Basic Description

Synonyms AMODIAQUINI HYDROCHLORIDUM [WHO-IP LATIN] | HY-B1322 | NCGC00017063-01 | NSC 755863 | SN 10751 | Tox21_110765 | NSC-755863 | 6398-98-7 (HCl hydrate) | AMODIAQUINE HYDROCHLORIDE [ORANGE BOOK] | Amodiaquini hydrochloridum | Amodiaquin HCl hydrate | Amodiaqu
Specifications & Purity ≥97%
Shipped In Normal
Action Type INHIBITOR
Mechanism of action Ferriprotoporphyrin IX inhibitor

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Quinolines and derivatives
Subclass Aminoquinolines and derivatives
Intermediate Tree Nodes Not available
Direct Parent 4-aminoquinolines
Alternative Parents Chloroquinolines  p-Aminophenols  Phenylmethylamines  Aniline and substituted anilines  Benzylamines  1-hydroxy-2-unsubstituted benzenoids  Aminopyridines and derivatives  Aralkylamines  Aryl chlorides  Heteroaromatic compounds  Trialkylamines  Secondary amines  Azacyclic compounds  Hydrocarbon derivatives  Hydrochlorides  Organic oxides  Organochlorides  Organooxygen compounds  Organopnictogen compounds  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents 4-aminoquinoline - Haloquinoline - Chloroquinoline - Aminophenol - P-aminophenol - Phenylmethylamine - Benzylamine - Aniline or substituted anilines - 1-hydroxy-2-unsubstituted benzenoid - Aminopyridine - Aralkylamine - Phenol - Pyridine - Monocyclic benzene moiety - Aryl halide - Benzenoid - Aryl chloride - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Azacycle - Secondary amine - Amine - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Hydrochloride - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as 4-aminoquinolines. These are organic compounds containing an amino group attached to the 4-position of a quinoline ring system.
External Descriptors hydrochloride

Associated Targets(Human)

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HepG2 (196354 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488183633
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183633
IUPAC Name 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;dihydrate;dihydrochloride
INCHI InChI=1S/C20H22ClN3O.2ClH.2H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);2*1H;2*1H2
InChIKey YVNAYSHNIILOJS-UHFFFAOYSA-N
Smiles CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.O.O.Cl.Cl
Isomeric SMILES CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.O.O.Cl.Cl
PubChem CID 64646
Molecular Weight 464.81

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number Certificate Type Date Item
B2317252 Certificate of Analysis Dec 17, 2024 A135245
B2317271 Certificate of Analysis Dec 17, 2024 A135245
B2317277 Certificate of Analysis Dec 17, 2024 A135245
B2317339 Certificate of Analysis Dec 06, 2024 A135245
B2317318 Certificate of Analysis Dec 06, 2024 A135245
B2317184 Certificate of Analysis Dec 06, 2024 A135245
D1524048 Certificate of Analysis Nov 15, 2022 A135245

Chemical and Physical Properties

Solubility Soluble in water; Soluble in Methanol; Very slightly soluble in Chloroform,Benzene,Ether; Insoluble in Alcohol
Molecular Weight 464.800 g/mol
XLogP3
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 6
Exact Mass 463.12 Da
Monoisotopic Mass 463.12 Da
Topological Polar Surface Area 50.400 Ų
Heavy Atom Count 29
Formal Charge 0
Complexity 406.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 5

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Ying Pan, Qiongjie Ding, Baohong Li, Xiaoxiong Wang, Yiwei Liu, Junhao Chen, Fei Ke, Jianqiang Liu.  (2021)  Self-adjusted bimetallic zeolitic-imidazolate framework-derived hierarchical magnetic carbon composites as efficient adsorbent for optimizing drug contaminant removal.  CHEMOSPHERE,  263  (128101). 

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