Skip to the beginning of the images gallery

Amlodipine Maleate , Voltage-gated L-type calcium channel blocker, CAS No.1357024-06-6, Voltage-gated L-type calcium channel blocker

COA

Cas Number: 1357024-06-6
Molecular Weight: 538.97
PubChem CID: 6435922

In stock

Item Number

A353265

Grouped product items
SKU	Size	Availability	Price	Qty
A353265-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$285.90

Basic Description

Synonyms	AMLODIPINE MALEATE [MART.] \| BCP12616 \| Amlodipine maleate [USAN] \| Amlodipine Maleate; 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester (Z)-2-butenedioate (1:1); Amlodipine maleate; UK
Shipped In	Normal
Action Type	BLOCKER
Mechanism of action	Voltage-gated L-type calcium channel blocker

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyridines and derivatives
    - Subclass Hydropyridines
      - Level5 Dihydropyridines
        Level6 Dihydropyridinecarboxylic acids and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyridines and derivatives
Subclass	Hydropyridines
Intermediate Tree Nodes	Dihydropyridines
Direct Parent	Dihydropyridinecarboxylic acids and derivatives
Alternative Parents	Chlorobenzenes Unsaturated fatty acids Aryl chlorides Dicarboxylic acids and derivatives Vinylogous amides Methyl esters Enoate esters Amino acids and derivatives Azacyclic compounds Carboxylic acids Dialkyl ethers Dialkylamines Enamines Monoalkylamines Organochlorides Carbonyl compounds Hydrocarbon derivatives Organic oxides
Molecular Framework	Not available
Substituents	Dihydropyridinecarboxylic acid derivative - Halobenzene - Chlorobenzene - Aryl chloride - Dicarboxylic acid or derivatives - Aryl halide - Unsaturated fatty acid - Benzenoid - Fatty acid - Monocyclic benzene moiety - Fatty acyl - Vinylogous amide - Methyl ester - Enoate ester - Alpha,beta-unsaturated carboxylic ester - Amino acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Azacycle - Carboxylic acid - Secondary amine - Dialkyl ether - Secondary aliphatic amine - Enamine - Ether - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Primary amine - Organooxygen compound - Carbonyl group - Amine - Organonitrogen compound - Primary aliphatic amine - Organohalogen compound - Organochloride - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as dihydropyridinecarboxylic acids and derivatives. These are compounds containing a dihydropyridine moiety bearing a carboxylic acid group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	(Z)-but-2-enedioic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
INCHI	InChI=1S/C20H25ClN2O5.C4H4O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;5-3(6)1-2-4(7)8/h5-8,17,23H,4,9-11,22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKey	TZNOWAJJWCGILX-BTJKTKAUSA-N
Smiles	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C(=CC(=O)O)C(=O)O
Isomeric SMILES	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C(=C\C(=O)O)\C(=O)O
PubChem CID	6435922
Molecular Weight	538.97

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	524.900 g/mol
XLogP3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	12
Exact Mass	524.156 Da
Monoisotopic Mass	524.156 Da
Topological Polar Surface Area	174.000 Å²
Heavy Atom Count	36
Formal Charge	0
Complexity	765.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	2

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration