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Amifostine Trihydrate - 10mM in Water, high purity , CAS No.112901-68-5

    Grade & Purity:
  • 10mM in Water
In stock
Item Number
A420668
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Availability
Price Qty
A420668-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$103.90

Basic Description

Synonyms Amifostine trihydrate | 112901-68-5 | Anifostine trihydrate | 112901-68-5 (trihydrate) | M487QF2F4V | NSC 296961 | S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate | Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihy
Specifications & Purity 10mM in Water
Biochemical and Physiological Mechanisms Radioprotective agent. Selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. Selectivity is due to preferential uptake by normal tissues and subsequent metabolic activation to 2-(3-aminopropyl)aminoethanethiol
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Application:

Amifostine may provide renal protection during PRRT using somatostatin analogs by mitigating radiation damage and reducing the absorbed kidney radiation dose. Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible.


Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organophosphorus compounds
Class Organothiophosphorus compounds
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Organothiophosphorus compounds
Alternative Parents Sulfenyl compounds  Dialkylamines  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  
Molecular Framework Aliphatic acyclic compounds
Substituents Sulfenyl compound - Secondary amine - Organothiophosphorus compound - Secondary aliphatic amine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organosulfur compound - Organonitrogen compound - Primary aliphatic amine - Amine - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as organothiophosphorus compounds. These are organic derivatives of thiophosphonic acid, thiophosphoric acid, dithiophosphoric acid, or phosphorotrithioic acid, or derivatives thereof. Thiophosphonic acid, dithiophosphoric acid, thiophosphoric acid, and phosphorotrithioic acid are thiophosphorus compounds with the formula OP(O)(=S), OP(S)(=S)O, OP(O)(=S)O, and OP(=S)(S)S, respectively.
External Descriptors Not available

Names and Identifiers

IUPAC Name 2-(3-aminopropylamino)ethylsulfanylphosphonic acid;trihydrate
INCHI InChI=1S/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2
InChIKey TXQPXJKRNHJWAX-UHFFFAOYSA-N
Smiles C(CN)CNCCSP(=O)(O)O.O.O.O
Isomeric SMILES C(CN)CNCCSP(=O)(O)O.O.O.O
WGK Germany 3
RTECS TE6491000
Molecular Weight 268.27
Reaxy-Rn 13570647
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13570647&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 268.270 g/mol
XLogP3
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 7
Exact Mass 268.086 Da
Monoisotopic Mass 268.086 Da
Topological Polar Surface Area 124.000 Ų
Heavy Atom Count 15
Formal Charge 0
Complexity 152.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 4

Solution Calculators

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